ES378348A1 - ((thenylidene amino)oxy)alkyl carboxylic acids and salts and esters thereof - Google Patents
((thenylidene amino)oxy)alkyl carboxylic acids and salts and esters thereofInfo
- Publication number
- ES378348A1 ES378348A1 ES378348A ES378348A ES378348A1 ES 378348 A1 ES378348 A1 ES 378348A1 ES 378348 A ES378348 A ES 378348A ES 378348 A ES378348 A ES 378348A ES 378348 A1 ES378348 A1 ES 378348A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- thenylidene
- oxy
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- -1 (thenylidene amino)oxy Chemical group 0.000 title 2
- 150000002148 esters Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel compounds of Formula I wherein R 1 and R 2 are H, halogen or methyl, R 3 is C 1-3 alkylene, R 4 is H, C 1-5 alkyl, an alkali metal atom, NH 4 , (C 2 H 5 ) 2 NH 2 , (C 2 H 5 ) 3 NH, (C 2 H 4 OH) 3 NH, (CH 3 ) 2 (C 2 H 4 OH)NH and (C 2 H 4 OH) 2 (C 2 H 5 )NH are prepared either by reaction of a compound of formula wherein M is a metal atom, which may be prepared in situ from the corresponding ketone and hydroxylamine, with a compound of formula where R1 4 is H or alkyl, optionally followed by salt formation or by reaction of a compound of Formula IV with a compound of formula Pharmaceutical compositions having antiinflammatory and analgesic activity being in conventional forms for oral, rectal or parenteral administration comprise an above novel compound and a carrier therefor.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL6905499A NL6905499A (en) | 1969-04-10 | 1969-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES378348A1 true ES378348A1 (en) | 1973-02-01 |
Family
ID=19806649
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES378348A Expired ES378348A1 (en) | 1969-04-10 | 1970-04-08 | ((thenylidene amino)oxy)alkyl carboxylic acids and salts and esters thereof |
| ES405385A Expired ES405385A1 (en) | 1969-04-10 | 1972-07-31 | ((thenylidene amino)oxy)alkyl carboxylic acids and salts and esters thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405385A Expired ES405385A1 (en) | 1969-04-10 | 1972-07-31 | ((thenylidene amino)oxy)alkyl carboxylic acids and salts and esters thereof |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3709911A (en) |
| AT (3) | AT301534B (en) |
| AU (1) | AU1349970A (en) |
| BE (1) | BE748682A (en) |
| CH (4) | CH542225A (en) |
| ES (2) | ES378348A1 (en) |
| FR (1) | FR2042318B1 (en) |
| GB (1) | GB1245549A (en) |
| IL (1) | IL34255A0 (en) |
| NL (1) | NL6905499A (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205682A1 (en) * | 1970-06-11 | 1976-05-31 | Philips Nv | METHOD OF PRODUCTION OF AMINO-OXYACETIC (4-CHLORO-ALPHA-METHYLBENZYLIDEN) ESTER (2-DIMETHYLAMINOETHYL) ACID AND ITS ACID ADDITION SALTS FORMED WITH PHARMACOLOGICALLY ACCEPTABLE ACIDS |
| DE2640484A1 (en) * | 1975-09-11 | 1977-04-07 | Philagro Sa | AMIDOXIM DERIVATIVES, THEIR PRODUCTION AND USE |
| IT1110460B (en) * | 1977-03-02 | 1985-12-23 | Ciba Geigy Ag | PRODUCTS THAT PROMOTE THE GROWTH OF PLANTS AND PRODUCTS THAT PROTECT PLANTS BASED ON BODY ETHERS AND BODY ESTERS THEIR PREPARATION AND USE |
| CH632130A5 (en) * | 1977-03-02 | 1982-09-30 | Ciba Geigy Ag | Compositions on the basis of oxime ethers, oxime esters or oxime carbamates which are suitable in agriculture for crop protection |
| US4467698A (en) * | 1981-11-16 | 1984-08-28 | Perrine Walter E | Angular shape firing pin for use with a collapsible toggle recoil in a hand held weapon |
| DE3528753A1 (en) * | 1985-08-10 | 1987-02-19 | Bayer Ag | SUBSTITUTED PYRAZOLIN-5-ONE |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH368169A (en) * | 1957-11-11 | 1963-03-31 | Ciba Geigy | Process for the preparation of new aminoalkoxy compounds |
-
1969
- 1969-04-10 NL NL6905499A patent/NL6905499A/xx unknown
-
1970
- 1970-04-07 AU AU13499/70A patent/AU1349970A/en not_active Expired
- 1970-04-07 CH CH1486372A patent/CH542225A/en not_active IP Right Cessation
- 1970-04-07 CH CH510470A patent/CH551435A/en not_active IP Right Cessation
- 1970-04-07 GB GB06340/70A patent/GB1245549A/en not_active Expired
- 1970-04-07 CH CH1486472A patent/CH542226A/en not_active IP Right Cessation
- 1970-04-07 AT AT196471A patent/AT301534B/en not_active IP Right Cessation
- 1970-04-07 AT AT196271A patent/AT299185B/en not_active IP Right Cessation
- 1970-04-07 IL IL34255A patent/IL34255A0/en unknown
- 1970-04-07 AT AT316270A patent/AT296278B/en not_active IP Right Cessation
- 1970-04-07 CH CH1486272A patent/CH549591A/en not_active IP Right Cessation
- 1970-04-08 BE BE748682D patent/BE748682A/en unknown
- 1970-04-08 ES ES378348A patent/ES378348A1/en not_active Expired
- 1970-04-08 FR FR707012653A patent/FR2042318B1/fr not_active Expired
- 1970-04-08 US US00026756A patent/US3709911A/en not_active Expired - Lifetime
-
1972
- 1972-07-31 ES ES405385A patent/ES405385A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH542226A (en) | 1973-11-15 |
| AU1349970A (en) | 1971-10-14 |
| GB1245549A (en) | 1971-09-08 |
| AT299185B (en) | 1972-06-12 |
| DE2016057B2 (en) | 1976-12-23 |
| NL6905499A (en) | 1970-10-13 |
| CH551435A (en) | 1974-07-15 |
| BE748682A (en) | 1970-10-08 |
| US3709911A (en) | 1973-01-09 |
| CH549591A (en) | 1974-05-31 |
| CH542225A (en) | 1973-11-15 |
| DE2016057A1 (en) | 1970-10-15 |
| ES405385A1 (en) | 1975-09-01 |
| FR2042318A1 (en) | 1971-02-12 |
| AT296278B (en) | 1972-02-10 |
| FR2042318B1 (en) | 1973-06-08 |
| IL34255A0 (en) | 1970-06-17 |
| AT301534B (en) | 1972-09-11 |
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