ES427900A1 - Substituted beta-lactams and their preparation - Google Patents

Substituted beta-lactams and their preparation

Info

Publication number
ES427900A1
ES427900A1 ES427900A ES427900A ES427900A1 ES 427900 A1 ES427900 A1 ES 427900A1 ES 427900 A ES427900 A ES 427900A ES 427900 A ES427900 A ES 427900A ES 427900 A1 ES427900 A1 ES 427900A1
Authority
ES
Spain
Prior art keywords
formula
represents hydrogen
halogen
lactams
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES427900A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES427900A1 publication Critical patent/ES427900A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A process for the preparation of new substituted beta-lactams of formula (I) ** formula ** where X represents hydrogen or halogen or an amino or substituted amino group, Y represents hydrogen or, in cases where X is hydrogen or halogen, Y can be halogen, R3 represents hydrogen or a group of formula (II) ** formula ** where R4 represents a carboxylic acid group or a salt, ester, thioester or amide derived from a carboxylic acid group and Z represents hydrogen or a alkyl, alkenyl, alkynyl or aryl group, the process of which is characterized by reacting with a oxidizing agent a compound of formula IV ** formula ** where X, Y, R3 and Z are those defined above (Machine-translation by Google Translate, not legally binding)
ES427900A 1971-02-04 1974-07-01 Substituted beta-lactams and their preparation Expired ES427900A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB388371A GB1368074A (en) 1971-02-04 1971-02-04 Substituted beta-lactams and their preparation

Publications (1)

Publication Number Publication Date
ES427900A1 true ES427900A1 (en) 1976-12-16

Family

ID=9766672

Family Applications (3)

Application Number Title Priority Date Filing Date
ES399347A Expired ES399347A1 (en) 1971-02-04 1972-01-31 Substituted beta-lactams and their preparation
ES427901A Expired ES427901A1 (en) 1971-02-04 1974-07-01 Substituted beta-lactams and their preparation
ES427900A Expired ES427900A1 (en) 1971-02-04 1974-07-01 Substituted beta-lactams and their preparation

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES399347A Expired ES399347A1 (en) 1971-02-04 1972-01-31 Substituted beta-lactams and their preparation
ES427901A Expired ES427901A1 (en) 1971-02-04 1974-07-01 Substituted beta-lactams and their preparation

Country Status (8)

Country Link
AU (1) AU3837272A (en)
BE (1) BE779016A (en)
DE (1) DE2205123A1 (en)
ES (3) ES399347A1 (en)
FR (1) FR2124251A1 (en)
GB (1) GB1368074A (en)
NL (1) NL7201386A (en)
ZA (1) ZA72166B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (en) * 1977-05-09 1979-01-18
AU3796278A (en) * 1977-07-13 1980-01-17 Glaxo Group Ltd Penams and azetidinones
EP0003960B1 (en) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them
JPS55133355A (en) * 1979-04-03 1980-10-17 Shionogi & Co Ltd Inversion of 3-amino group of beta-lactam ring
EP0023887B1 (en) * 1979-08-01 1984-11-07 Ciba-Geigy Ag 3-substituted bicyclic azetidinone derivatives, process for their preparation, and intermediates as well as their preparation
EP0232966B1 (en) * 1986-01-17 1997-10-08 Beecham Group Plc Process for the preparation of penem compounds and intermediates for this preparation

Also Published As

Publication number Publication date
BE779016A (en) 1972-08-04
GB1368074A (en) 1974-09-25
NL7201386A (en) 1972-08-08
ZA72166B (en) 1972-09-27
FR2124251A1 (en) 1972-09-22
AU3837272A (en) 1973-08-02
ES399347A1 (en) 1975-06-01
ES427901A1 (en) 1976-12-16
DE2205123A1 (en) 1972-08-10

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