ES300123A1 - A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES300123A1 ES300123A1 ES300123A ES300123A ES300123A1 ES 300123 A1 ES300123 A1 ES 300123A1 ES 300123 A ES300123 A ES 300123A ES 300123 A ES300123 A ES 300123A ES 300123 A1 ES300123 A1 ES 300123A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- see formula
- formula
- above significance
- piperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of novel asymmetrically substituted piperazine derivatives of the general formula I ** (See formula) ** wherein R1, R2, and R3, as well as R'1, R'2 and R'3 mean the same or different alkoxy groups containing from 1 to 4 carbon atoms, but each of these three substituents can also mean hydrogen, A is a straight or branched alkoxylenic chain of 1 to 6 carbon atoms, which is optionally substituted by halogen atoms or interrupted by oxygen atoms, B represents a direct chemical bond or a group -OA'- where A ' has the same meaning as A, as well as its> salts by addition of acid and quaternary derivatives, characterized in that: a) a piperazine derivative of the general formula II is reacted ** (See formula) ** wherein R'1, R'2, R'3, A and B have the above significance, with a derivative capable of reacting, such as for example halogen, ester or amide of a benzoic acid substituted by alkoxy of the general formula III ** (See formula) ** wherein R1, R2 and R3 have the above significance, while X means a group capable of reacting, preferably a halogen atom; or b) reacts a piperazine derivative of the general formula IV ** (See formula) ** wherein R1, R2 and R3 have the above significance, with a combination of general formula V ** (See formula) ** where R'1, R'2, R'3, A, B and X have the above significance; or c) a piperazine derivative of the general formula VI is esterified ** (See formula) ** where R1, R2, R3, A and B have the above meaning, with a combination of general formula VII ** (See formula) ** wherein R'1, R'2, R'3 and X have the above significance, and eventually, the products obtained by the above methods are transformed in a manner known per se into salts by addition of acid or quaternary derivatives. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES300123A ES300123A1 (en) | 1964-05-22 | 1964-05-22 | A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES300123A ES300123A1 (en) | 1964-05-22 | 1964-05-22 | A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES300123A1 true ES300123A1 (en) | 1964-11-16 |
Family
ID=66585675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES300123A Expired ES300123A1 (en) | 1964-05-22 | 1964-05-22 | A procedure for the preparation of new derivatives of piperazine replaced asymmetrically (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES300123A1 (en) |
-
1964
- 1964-05-22 ES ES300123A patent/ES300123A1/en not_active Expired
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