CH611887A5 - Process for the preparation of novel acid amides - Google Patents

Process for the preparation of novel acid amides

Info

Publication number
CH611887A5
CH611887A5 CH498578A CH498578A CH611887A5 CH 611887 A5 CH611887 A5 CH 611887A5 CH 498578 A CH498578 A CH 498578A CH 498578 A CH498578 A CH 498578A CH 611887 A5 CH611887 A5 CH 611887A5
Authority
CH
Switzerland
Prior art keywords
acid amides
preparation
novel acid
prepared
novel
Prior art date
Application number
CH498578A
Inventor
Eberhard Dr Kutter
Volkhard Dr Austel
Joachim Dr Kaehling
Harald Dr Ziegler
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH611887A5 publication Critical patent/CH611887A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/14—Monocyclic dicarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

There are prepared novel acid amides of the formula I <IMAGE> in which R1 to R3, which are identical or different, denote hydrogen or alkyl having 1 to 3 carbon atoms. The novel compounds are distinguished by useful pharmacological properties, in particular by muscle-relaxant, sedating, antiarrhythmic and anticonvulsive actions. They are prepared, starting from the corresponding isoquinolinediones, by reaction with appropriately substituted glycinamides or their acid addition salts.
CH498578A 1972-08-01 1978-05-07 Process for the preparation of novel acid amides CH611887A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2237770A DE2237770A1 (en) 1972-08-01 1972-08-01 NEW ACID AMID

Publications (1)

Publication Number Publication Date
CH611887A5 true CH611887A5 (en) 1979-06-29

Family

ID=5852334

Family Applications (6)

Application Number Title Priority Date Filing Date
CH1106573A CH615918A5 (en) 1972-08-01 1973-07-30 Process for the preparation of novel acid amides
CH498578A CH611887A5 (en) 1972-08-01 1978-05-07 Process for the preparation of novel acid amides
CH498678A CH615423A5 (en) 1972-08-01 1978-05-08 Process for the preparation of novel acid amides
CH638978A CH611888A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides
CH638878A CH612184A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides
CH639078A CH611280A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1106573A CH615918A5 (en) 1972-08-01 1973-07-30 Process for the preparation of novel acid amides

Family Applications After (4)

Application Number Title Priority Date Filing Date
CH498678A CH615423A5 (en) 1972-08-01 1978-05-08 Process for the preparation of novel acid amides
CH638978A CH611888A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides
CH638878A CH612184A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides
CH639078A CH611280A5 (en) 1972-08-01 1978-06-12 Process for the preparation of novel acid amides

Country Status (12)

Country Link
JP (1) JPS558973B2 (en)
AT (2) AT329059B (en)
AU (1) AU476552B2 (en)
BE (1) BE803086A (en)
CH (6) CH615918A5 (en)
DE (1) DE2237770A1 (en)
DK (1) DK137008C (en)
ES (6) ES417443A1 (en)
FI (1) FI52218C (en)
FR (1) FR2194435A1 (en)
GB (1) GB1450793A (en)
NL (1) NL7310562A (en)

Also Published As

Publication number Publication date
ES422933A1 (en) 1976-06-16
GB1450793A (en) 1976-09-29
ES422929A1 (en) 1976-06-16
ATA673773A (en) 1975-07-15
FR2194435A1 (en) 1974-03-01
DK137008C (en) 1978-05-22
JPS558973B2 (en) 1980-03-07
ES422930A1 (en) 1976-06-16
ATA225975A (en) 1975-07-15
CH612184A5 (en) 1979-07-13
AU5873573A (en) 1975-02-06
CH615918A5 (en) 1980-02-29
FI52218C (en) 1977-07-11
JPS4980080A (en) 1974-08-02
AT329060B (en) 1976-04-26
ES422932A1 (en) 1976-06-16
FI52218B (en) 1977-03-31
BE803086A (en) 1974-01-31
AU476552B2 (en) 1976-09-30
DK137008B (en) 1978-01-02
NL7310562A (en) 1974-02-05
CH615423A5 (en) 1980-01-31
ES422931A1 (en) 1976-06-16
ES417443A1 (en) 1976-03-16
CH611280A5 (en) 1979-05-31
CH611888A5 (en) 1979-06-29
DE2237770A1 (en) 1974-02-14
AT329059B (en) 1976-04-26

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Legal Events

Date Code Title Description
PL Patent ceased