DE69115135D1 - 1-Alkyl-3-(Acylamino)-Epsilon-Caprolactame zur Verbesserung der Lernfähigkeit und des Gedächtnisses und diese enthaltende pharmazeutische Zubereitungen. - Google Patents
1-Alkyl-3-(Acylamino)-Epsilon-Caprolactame zur Verbesserung der Lernfähigkeit und des Gedächtnisses und diese enthaltende pharmazeutische Zubereitungen.Info
- Publication number
- DE69115135D1 DE69115135D1 DE69115135T DE69115135T DE69115135D1 DE 69115135 D1 DE69115135 D1 DE 69115135D1 DE 69115135 T DE69115135 T DE 69115135T DE 69115135 T DE69115135 T DE 69115135T DE 69115135 D1 DE69115135 D1 DE 69115135D1
- Authority
- DE
- Germany
- Prior art keywords
- acylamino
- epsilon
- alkyl
- memory
- caprolactams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT04808790A IT1247698B (it) | 1990-06-21 | 1990-06-21 | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69115135D1 true DE69115135D1 (de) | 1996-01-18 |
DE69115135T2 DE69115135T2 (de) | 1996-05-09 |
Family
ID=11264450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69115135T Expired - Fee Related DE69115135T2 (de) | 1990-06-21 | 1991-06-20 | 1-Alkyl-3-(Acylamino)-Epsilon-Caprolactame zur Verbesserung der Lernfähigkeit und des Gedächtnisses und diese enthaltende pharmazeutische Zubereitungen. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5155102A (de) |
EP (1) | EP0462949B1 (de) |
JP (1) | JPH04230266A (de) |
AT (1) | ATE131159T1 (de) |
DE (1) | DE69115135T2 (de) |
DK (1) | DK0462949T3 (de) |
ES (1) | ES2081463T3 (de) |
GR (1) | GR3019076T3 (de) |
IT (1) | IT1247698B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU756174B2 (en) * | 1999-02-09 | 2003-01-09 | Bristol-Myers Squibb Company | Lactam inhibitors of FXa and method |
WO2000047207A1 (en) | 1999-02-09 | 2000-08-17 | Bristol-Myers Squibb Company | LACTAM INHIBITORS OF FXa AND METHOD |
US6344450B1 (en) | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
US6511973B2 (en) | 2000-08-02 | 2003-01-28 | Bristol-Myers Squibb Co. | Lactam inhibitors of FXa and method |
CN103393691A (zh) * | 2003-12-01 | 2013-11-20 | 剑桥企业有限公司 | 抗炎药 |
EP1732885A1 (de) * | 2004-02-23 | 2006-12-20 | Trustees Of Tufts College | Lactame als konformationsgehinderte peptidomimetische inhibitoren |
GB2418425B (en) * | 2004-08-11 | 2008-09-03 | Univ Cambridge Tech | Anti-inflammatory agents |
GB201009603D0 (en) | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1231921B (it) * | 1989-06-12 | 1992-01-15 | Sigma Tau Ind Farmaceuti | 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
IT1231477B (it) * | 1989-07-12 | 1991-12-07 | Sigma Tau Ind Farmaceuti | (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
-
1990
- 1990-06-21 IT IT04808790A patent/IT1247698B/it active IP Right Grant
-
1991
- 1991-06-20 AT AT91830276T patent/ATE131159T1/de not_active IP Right Cessation
- 1991-06-20 ES ES91830276T patent/ES2081463T3/es not_active Expired - Lifetime
- 1991-06-20 EP EP91830276A patent/EP0462949B1/de not_active Expired - Lifetime
- 1991-06-20 DE DE69115135T patent/DE69115135T2/de not_active Expired - Fee Related
- 1991-06-20 DK DK91830276.1T patent/DK0462949T3/da active
- 1991-06-21 JP JP3150301A patent/JPH04230266A/ja active Pending
- 1991-06-21 US US07/718,645 patent/US5155102A/en not_active Expired - Fee Related
-
1996
- 1996-02-22 GR GR960400482T patent/GR3019076T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69115135T2 (de) | 1996-05-09 |
IT9048087A0 (it) | 1990-06-21 |
GR3019076T3 (en) | 1996-05-31 |
IT1247698B (it) | 1994-12-30 |
EP0462949B1 (de) | 1995-12-06 |
JPH04230266A (ja) | 1992-08-19 |
US5155102A (en) | 1992-10-13 |
DK0462949T3 (da) | 1996-02-05 |
EP0462949A1 (de) | 1991-12-27 |
IT9048087A1 (it) | 1991-12-21 |
ATE131159T1 (de) | 1995-12-15 |
ES2081463T3 (es) | 1996-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |