IT1245870B - 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti - Google Patents

3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti

Info

Publication number
IT1245870B
IT1245870B ITRM910391A ITRM910391A IT1245870B IT 1245870 B IT1245870 B IT 1245870B IT RM910391 A ITRM910391 A IT RM910391A IT RM910391 A ITRM910391 A IT RM910391A IT 1245870 B IT1245870 B IT 1245870B
Authority
IT
Italy
Prior art keywords
memory
acylamin
pyrolidinone
activators
compounds
Prior art date
Application number
ITRM910391A
Other languages
English (en)
Inventor
Fabio Giannessi
Orlando Ghirardi
Domenico Misiti
Maria Ornella Tinti
Roberto Cozzolino
Carlo Scolastico
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to ITRM910391A priority Critical patent/IT1245870B/it
Publication of ITRM910391A0 publication Critical patent/ITRM910391A0/it
Priority to ES92830293T priority patent/ES2078723T3/es
Priority to DE69205073T priority patent/DE69205073T2/de
Priority to EP92830293A priority patent/EP0519877B1/en
Priority to DK92830293.4T priority patent/DK0519877T3/da
Priority to AT92830293T priority patent/ATE128461T1/de
Publication of ITRM910391A1 publication Critical patent/ITRM910391A1/it
Application granted granted Critical
Publication of IT1245870B publication Critical patent/IT1245870B/it
Priority to GR950403292T priority patent/GR3018173T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
ITRM910391A 1991-06-05 1991-06-05 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti IT1245870B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITRM910391A IT1245870B (it) 1991-06-05 1991-06-05 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti
ES92830293T ES2078723T3 (es) 1991-06-05 1992-06-04 3-acilamino-2-pirrolidinonas como potenciadores de los procesos de aprendizaje y de la memoria y composiciones farmaceuticas que las contienen.
DE69205073T DE69205073T2 (de) 1991-06-05 1992-06-04 3-Acylamino-2-pyrrolidinone zur Verbesserung der Lernfähigkeit und des Gedächtnisses und diese enthaltende pharmazeutische Zubereitungen.
EP92830293A EP0519877B1 (en) 1991-06-05 1992-06-04 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same
DK92830293.4T DK0519877T3 (da) 1991-06-05 1992-06-04 3-acylamino-2-pyrrolidioner som forstærkere af indlærings- og hukommelsesprocesserne og farmaceutiske præparater, der indeholder samme
AT92830293T ATE128461T1 (de) 1991-06-05 1992-06-04 3-acylamino-2-pyrrolidinone zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen.
GR950403292T GR3018173T3 (en) 1991-06-05 1995-11-22 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910391A IT1245870B (it) 1991-06-05 1991-06-05 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti

Publications (3)

Publication Number Publication Date
ITRM910391A0 ITRM910391A0 (it) 1991-06-05
ITRM910391A1 ITRM910391A1 (it) 1992-12-05
IT1245870B true IT1245870B (it) 1994-10-25

Family

ID=11400180

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910391A IT1245870B (it) 1991-06-05 1991-06-05 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti

Country Status (7)

Country Link
EP (1) EP0519877B1 (it)
AT (1) ATE128461T1 (it)
DE (1) DE69205073T2 (it)
DK (1) DK0519877T3 (it)
ES (1) ES2078723T3 (it)
GR (1) GR3018173T3 (it)
IT (1) IT1245870B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
GB0512238D0 (en) * 2005-06-15 2005-07-27 Univ Cambridge Tech Anti-inflammatory agents
US7662967B2 (en) 2007-08-02 2010-02-16 Cambridge Enterprise Limited Anti-inflammatory compounds and compositions
GB2452696B (en) 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
CN106366031B (zh) * 2016-08-30 2018-11-06 山东默得森生物制药有限公司 一种(s)-4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2960194D1 (en) * 1978-05-08 1981-04-16 Ucb Sa Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1231477B (it) * 1989-07-12 1991-12-07 Sigma Tau Ind Farmaceuti (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti

Also Published As

Publication number Publication date
EP0519877B1 (en) 1995-09-27
ATE128461T1 (de) 1995-10-15
ITRM910391A0 (it) 1991-06-05
ES2078723T3 (es) 1995-12-16
ITRM910391A1 (it) 1992-12-05
EP0519877A1 (en) 1992-12-23
DE69205073T2 (de) 1996-03-07
GR3018173T3 (en) 1996-02-29
DE69205073D1 (de) 1995-11-02
DK0519877T3 (da) 1995-11-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950518