ATE128461T1 - 3-acylamino-2-pyrrolidinone zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen. - Google Patents
3-acylamino-2-pyrrolidinone zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen.Info
- Publication number
- ATE128461T1 ATE128461T1 AT92830293T AT92830293T ATE128461T1 AT E128461 T1 ATE128461 T1 AT E128461T1 AT 92830293 T AT92830293 T AT 92830293T AT 92830293 T AT92830293 T AT 92830293T AT E128461 T1 ATE128461 T1 AT E128461T1
- Authority
- AT
- Austria
- Prior art keywords
- acylamino
- memory
- pyrrolidinone
- same
- pharmaceutical preparations
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- -1 p-methoxybenzoyl Chemical group 0.000 abstract 6
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- FATAVLOOLIRUNA-UHFFFAOYSA-N formylmethyl Chemical group [CH2]C=O FATAVLOOLIRUNA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM910391A IT1245870B (it) | 1991-06-05 | 1991-06-05 | 3-acilammino-2-pirrolidinoni quali attivatori dei processi di appremdimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE128461T1 true ATE128461T1 (de) | 1995-10-15 |
Family
ID=11400180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92830293T ATE128461T1 (de) | 1991-06-05 | 1992-06-04 | 3-acylamino-2-pyrrolidinone zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0519877B1 (de) |
| AT (1) | ATE128461T1 (de) |
| DE (1) | DE69205073T2 (de) |
| DK (1) | DK0519877T3 (de) |
| ES (1) | ES2078723T3 (de) |
| GR (1) | GR3018173T3 (de) |
| IT (1) | IT1245870B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| GB0512238D0 (en) * | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| CN106366031B (zh) * | 2016-08-30 | 2018-11-06 | 山东默得森生物制药有限公司 | 一种(s)-4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2960194D1 (en) * | 1978-05-08 | 1981-04-16 | Ucb Sa | Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IT1231477B (it) * | 1989-07-12 | 1991-12-07 | Sigma Tau Ind Farmaceuti | (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
-
1991
- 1991-06-05 IT ITRM910391A patent/IT1245870B/it active IP Right Grant
-
1992
- 1992-06-04 DE DE69205073T patent/DE69205073T2/de not_active Expired - Fee Related
- 1992-06-04 EP EP92830293A patent/EP0519877B1/de not_active Expired - Lifetime
- 1992-06-04 DK DK92830293.4T patent/DK0519877T3/da active
- 1992-06-04 ES ES92830293T patent/ES2078723T3/es not_active Expired - Lifetime
- 1992-06-04 AT AT92830293T patent/ATE128461T1/de not_active IP Right Cessation
-
1995
- 1995-11-22 GR GR950403292T patent/GR3018173T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0519877B1 (de) | 1995-09-27 |
| ITRM910391A0 (it) | 1991-06-05 |
| ES2078723T3 (es) | 1995-12-16 |
| ITRM910391A1 (it) | 1992-12-05 |
| EP0519877A1 (de) | 1992-12-23 |
| DE69205073T2 (de) | 1996-03-07 |
| GR3018173T3 (en) | 1996-02-29 |
| DE69205073D1 (de) | 1995-11-02 |
| DK0519877T3 (da) | 1995-11-27 |
| IT1245870B (it) | 1994-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |