ES2390272T3 - Agentes antiinflamatorios - Google Patents
Agentes antiinflamatorios Download PDFInfo
- Publication number
- ES2390272T3 ES2390272T3 ES04798708T ES04798708T ES2390272T3 ES 2390272 T3 ES2390272 T3 ES 2390272T3 ES 04798708 T ES04798708 T ES 04798708T ES 04798708 T ES04798708 T ES 04798708T ES 2390272 T3 ES2390272 T3 ES 2390272T3
- Authority
- ES
- Spain
- Prior art keywords
- caprolactam
- amino
- mmol
- carbon atoms
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0327775 | 2003-12-01 | ||
| GB0327775A GB0327775D0 (en) | 2003-12-01 | 2003-12-01 | Anti-inflammatory agents |
| GB0417436A GB0417436D0 (en) | 2004-08-05 | 2004-08-05 | Anti-inflammatory agents |
| GB0417436 | 2004-08-05 | ||
| GB0417734A GB0417734D0 (en) | 2004-08-10 | 2004-08-10 | Anti-Inflammatory agents |
| GB0417734 | 2004-08-10 | ||
| PCT/GB2004/005030 WO2005053702A2 (en) | 2003-12-01 | 2004-11-30 | Anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2390272T3 true ES2390272T3 (es) | 2012-11-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04798708T Expired - Lifetime ES2390272T3 (es) | 2003-12-01 | 2004-11-30 | Agentes antiinflamatorios |
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| Country | Link |
|---|---|
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| EP (2) | EP1691814B9 (enExample) |
| JP (1) | JP5248779B2 (enExample) |
| KR (1) | KR101228268B1 (enExample) |
| CN (1) | CN103393691A (enExample) |
| AR (1) | AR047730A1 (enExample) |
| CA (1) | CA2547651C (enExample) |
| CY (1) | CY1113171T1 (enExample) |
| DK (1) | DK1691814T3 (enExample) |
| ES (1) | ES2390272T3 (enExample) |
| IL (1) | IL175857A0 (enExample) |
| PL (1) | PL1691814T3 (enExample) |
| PT (1) | PT1691814E (enExample) |
| SI (1) | SI1691814T1 (enExample) |
| TW (1) | TWI356821B (enExample) |
| WO (1) | WO2005053702A2 (enExample) |
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| GB2418426A (en) | 2004-08-18 | 2006-03-29 | Univ Cambridge Tech | Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders |
| AU2011226837B2 (en) * | 2004-09-02 | 2014-09-18 | Cambridge Enterprise Limited | Ligands for G-protein coupled receptors |
| GB2418427A (en) * | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| GB0512238D0 (en) * | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| GB2455539B (en) * | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| GB201009603D0 (en) | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
| JP6173352B2 (ja) * | 2012-02-15 | 2017-08-02 | アニダ ファーマ インコーポレイテッド | 筋萎縮性側索硬化症の治療方法 |
| EP3570827B1 (en) * | 2017-01-18 | 2025-06-25 | Universitat Autònoma de Barcelona | Maresin for use in treating multiple sclerosis and amyotrophic lateral sclerosis |
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| GB327775A (en) | 1929-01-21 | 1930-04-17 | John Harry Grayson | Improvements in thermostats |
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| US3697562A (en) * | 1969-10-17 | 1972-10-10 | Allied Chem | Novel fluorocarbon diamides |
| JPS53121781A (en) * | 1977-03-30 | 1978-10-24 | Torii Yakuhin Kk | Caprolactum derivatives |
| JPS625994A (ja) * | 1985-07-02 | 1987-01-12 | Toray Ind Inc | リジン誘導体の製造法 |
| EP0312157A3 (en) * | 1987-10-13 | 1990-07-25 | Merck & Co. Inc. | Tetrapeptide renin inhibitors having a novel c-terminal amino acid |
| JP3054738B2 (ja) * | 1988-07-22 | 2000-06-19 | 武田薬品工業株式会社 | チアゾロ［５，４―ｂ］アゼピン誘導体 |
| DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
| US5430022A (en) * | 1990-05-14 | 1995-07-04 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound and its preparation |
| IT1247698B (it) * | 1990-06-21 | 1994-12-30 | Sigma Tau Ind Farmaceuti | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
| IT1254471B (it) * | 1992-02-27 | 1995-09-25 | Magis Farmaceutici | Derivati ammidici della (r)-glicerofosforil-(s)-serina o del suo diacil derivato, un processo per la loro preparazione e relative composizioni farmaceutiche per il potenziamento dei processi di apprendimento |
| US5821231A (en) * | 1993-12-06 | 1998-10-13 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using same |
| WO1996026183A1 (en) * | 1995-02-22 | 1996-08-29 | Novartis Ag | 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists |
| SG64939A1 (en) * | 1995-07-17 | 2002-02-19 | Mitsui Chemicals Inc | Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer |
| JP3633060B2 (ja) | 1995-09-22 | 2005-03-30 | Ｊｓｒ株式会社 | 低結晶性エチレン系ランダム共重合体およびその組成物 |
| US5817757A (en) * | 1995-10-30 | 1998-10-06 | Merck & Co., Inc. | Inhibitors of peptide binding to MHO class II proteins |
| ES2293651T3 (es) * | 1995-11-28 | 2008-03-16 | Cephalon, Inc. | Inhibidores de cisteina y serina proteasas derivados de aminoacidos d. |
| MY132550A (en) * | 1996-08-22 | 2007-10-31 | Novartis Ag | Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists |
| GB9621836D0 (en) * | 1996-10-19 | 1996-12-11 | Zeneca Ltd | Peptide compounds |
| DK0951466T3 (da) * | 1996-12-23 | 2009-03-16 | Elan Pharm Inc | Cycloalkyl-, lactam, lacton- og beslægtede forbindelser, farmaceutiske sammensætninger, der omfatter samme, og fremgangsmåder til inhibering af beta-amyloidpeptidfrigivelse og/eller dets syntese ved anvendelse af sådanne forbindelser |
| US6989435B2 (en) | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6506782B1 (en) * | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| CN1181817C (zh) * | 1998-03-20 | 2004-12-29 | 第一三得利制药株式会社 | 以苯基甲苯醌为有效成分的NF-kB抑制剂 |
| US6395282B1 (en) | 1998-04-16 | 2002-05-28 | University Of Rochester | Immunogenic conjugates of Gram-negative bacterial autoinducer molecules |
| HRP990246A2 (en) * | 1998-08-07 | 2000-06-30 | Du Pont Pharm Co | Succinoylamino benzodiazepines as inhibitors of a beta protein production |
| US6117870A (en) * | 1998-11-12 | 2000-09-12 | Fujirebio Kabushiki Kaisha | Cyclic amide derivatives |
| EP2386565A3 (en) | 1999-01-12 | 2013-11-20 | Cambridge Enterprise Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US6344450B1 (en) * | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
| AU2001243601A1 (en) * | 2000-03-10 | 2001-09-24 | Ariad Pharmaceuticals, Inc. | Caprolactam derivatives and uses thereof |
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2004
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- 2004-11-30 US US10/581,274 patent/US20080227724A1/en not_active Abandoned
- 2004-11-30 EP EP04798708A patent/EP1691814B9/en not_active Expired - Lifetime
- 2004-11-30 WO PCT/GB2004/005030 patent/WO2005053702A2/en not_active Ceased
- 2004-11-30 SI SI200431939T patent/SI1691814T1/sl unknown
- 2004-11-30 JP JP2006542002A patent/JP5248779B2/ja not_active Expired - Lifetime
- 2004-11-30 ES ES04798708T patent/ES2390272T3/es not_active Expired - Lifetime
- 2004-11-30 PT PT04798708T patent/PT1691814E/pt unknown
- 2004-11-30 EP EP10011516A patent/EP2279741A3/en not_active Withdrawn
- 2004-11-30 CN CN2013103149649A patent/CN103393691A/zh active Pending
- 2004-11-30 TW TW093136880A patent/TWI356821B/zh not_active IP Right Cessation
- 2004-11-30 PL PL04798708T patent/PL1691814T3/pl unknown
- 2004-11-30 DK DK04798708.6T patent/DK1691814T3/da active
- 2004-11-30 CA CA2547651A patent/CA2547651C/en not_active Expired - Fee Related
- 2004-12-01 AR ARP040104477A patent/AR047730A1/es not_active Application Discontinuation
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2006
- 2006-05-23 IL IL175857A patent/IL175857A0/en unknown
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2012
- 2012-10-04 CY CY20121100921T patent/CY1113171T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI356821B (en) | 2012-01-21 |
| WO2005053702A2 (en) | 2005-06-16 |
| HK1094680A1 (en) | 2007-04-04 |
| CA2547651C (en) | 2015-06-23 |
| WO2005053702A3 (en) | 2005-09-15 |
| US20080227724A1 (en) | 2008-09-18 |
| EP2279741A2 (en) | 2011-02-02 |
| EP1691814B1 (en) | 2012-07-25 |
| SI1691814T1 (sl) | 2012-11-30 |
| EP2279741A3 (en) | 2011-06-01 |
| PT1691814E (pt) | 2012-10-16 |
| JP2007512387A (ja) | 2007-05-17 |
| CY1113171T1 (el) | 2016-04-13 |
| JP5248779B2 (ja) | 2013-07-31 |
| EP1691814A2 (en) | 2006-08-23 |
| KR20070018807A (ko) | 2007-02-14 |
| KR101228268B1 (ko) | 2013-01-31 |
| AR047730A1 (es) | 2006-02-15 |
| EP1691814B9 (en) | 2013-02-20 |
| CA2547651A1 (en) | 2005-06-16 |
| CN103393691A (zh) | 2013-11-20 |
| DK1691814T3 (da) | 2012-10-29 |
| IL175857A0 (en) | 2008-02-09 |
| TW200526585A (en) | 2005-08-16 |
| PL1691814T3 (pl) | 2012-12-31 |
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