PT1654284E - Processo para preparar uma solução de alfa-1-antitripsina - Google Patents

Processo para preparar uma solução de alfa-1-antitripsina Download PDF

Info

Publication number
PT1654284E
PT1654284E PT04764046T PT04764046T PT1654284E PT 1654284 E PT1654284 E PT 1654284E PT 04764046 T PT04764046 T PT 04764046T PT 04764046 T PT04764046 T PT 04764046T PT 1654284 E PT1654284 E PT 1654284E
Authority
PT
Portugal
Prior art keywords
a1at
preparing
alpha
detergents
antitrypsin solution
Prior art date
Application number
PT04764046T
Other languages
English (en)
Portuguese (pt)
Inventor
Juergen Roemisch
Petra Schulz
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of PT1654284E publication Critical patent/PT1654284E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT04764046T 2003-08-12 2004-08-12 Processo para preparar uma solução de alfa-1-antitripsina PT1654284E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49409703P 2003-08-12 2003-08-12

Publications (1)

Publication Number Publication Date
PT1654284E true PT1654284E (pt) 2009-07-06

Family

ID=34135316

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04764046T PT1654284E (pt) 2003-08-12 2004-08-12 Processo para preparar uma solução de alfa-1-antitripsina

Country Status (22)

Country Link
US (1) US20060194300A1 (enExample)
EP (1) EP1654284B1 (enExample)
JP (1) JP4668904B2 (enExample)
KR (1) KR20060070543A (enExample)
CN (1) CN1867582B (enExample)
AT (1) ATE428730T1 (enExample)
AU (1) AU2004262578B2 (enExample)
BR (1) BRPI0412835A (enExample)
CA (1) CA2534900A1 (enExample)
DE (1) DE602004020632D1 (enExample)
DK (1) DK1654284T3 (enExample)
ES (1) ES2324168T3 (enExample)
IL (1) IL172868A0 (enExample)
NO (1) NO20060109L (enExample)
PL (1) PL1654284T3 (enExample)
PT (1) PT1654284E (enExample)
RS (1) RS20060077A (enExample)
RU (1) RU2370500C2 (enExample)
SI (1) SI1654284T1 (enExample)
UA (1) UA86775C2 (enExample)
WO (1) WO2005014648A1 (enExample)
ZA (1) ZA200601206B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1664123T4 (da) * 2003-09-22 2012-03-05 Kamada Ltd Storskalafremstilling af alfa-1-proteinaseinhibitor og anvendelse deraf
ES2246694B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Nanoparticulas pegiladas.
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
CN100354301C (zh) * 2005-10-13 2007-12-12 南京工业大学 化学合成多肽的新型大规模分离制备技术
CN100562523C (zh) * 2006-07-26 2009-11-25 河北大安制药有限公司 α1-抗胰蛋白酶的制备方法
US20110002909A1 (en) * 2007-11-02 2011-01-06 Vikram Arora Method, composition, and article of manufacture for providing alpha-1 antitrypsin
CN102127165B (zh) * 2010-01-15 2013-09-04 上海莱士血液制品股份有限公司 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺
CN102731642B (zh) * 2011-04-14 2014-01-29 上海莱士血液制品股份有限公司 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺
US9353165B2 (en) * 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
AU2013205138B2 (en) * 2012-08-09 2015-06-25 Grifols, S.A. Caprylate Viral Deactivation
US10906953B2 (en) * 2015-06-26 2021-02-02 Ferring B.V. Methods of purification and/or viral inactivation
AU2017214678B2 (en) * 2016-02-03 2024-02-01 Plasma Technologies, Llc Methods for extracting proteins from a blood-based material
WO2019086463A1 (en) 2017-10-30 2019-05-09 Baxalta GmbH Environmentally compatible detergents for inactivation of lipid-enveloped viruses
CN111991571B (zh) * 2020-08-12 2022-04-05 湖州师范学院 一种柱上低pH病毒灭活的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS584728A (ja) * 1981-05-01 1983-01-11 メデイカル・リサ−チ・インステイチユ−ト・オブ・サンフランシスコ・コ−ポレ−シヨン α−１−抗トリプシンの精製
US4379087A (en) * 1982-06-17 1983-04-05 Cutter Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4684723A (en) * 1985-09-11 1987-08-04 Miles Laboratories, Inc. Method of separating proteins from aqueous solutions
US4629567A (en) * 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
DE3877041T2 (de) * 1987-04-27 1993-04-22 Miles Inc Verfahren zur herstellung von hochgereinigtem alpha-1-proteinase-inhibitor.
KR920005689B1 (ko) * 1989-12-21 1992-07-13 국제약품공업주식회사 혈청으로부터 알파-1-안티트립신의 분리 정제 및 혈중 알파-1-안티트립신 양의 검정키트
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
SE9301582D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
DE4407837C1 (de) * 1994-03-09 1995-08-17 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem alpha¶1¶-Antitrypsin mittels Anionenaustauscher-Chromatographie
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
EP1736483A3 (en) * 1995-09-07 2008-07-30 Pharming Intellectual Property BV Purification of alpha-1 proteinase inhibitor
JP4105249B2 (ja) * 1996-08-09 2008-06-25 財団法人化学及血清療法研究所 α２プラスミンインヒビターの製造方法
AT407114B (de) * 1997-06-10 2000-12-27 Immuno Ag Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
WO2005014648A1 (en) 2005-02-17
SI1654284T1 (sl) 2009-10-31
CA2534900A1 (en) 2005-02-17
NO20060109L (no) 2006-02-15
CN1867582B (zh) 2010-06-16
JP2007523883A (ja) 2007-08-23
RS20060077A (sr) 2008-08-07
AU2004262578A1 (en) 2005-02-17
EP1654284B1 (en) 2009-04-15
RU2370500C2 (ru) 2009-10-20
KR20060070543A (ko) 2006-06-23
DK1654284T3 (da) 2009-07-20
IL172868A0 (en) 2006-06-11
AU2004262578B2 (en) 2010-05-06
ES2324168T3 (es) 2009-07-31
JP4668904B2 (ja) 2011-04-13
EP1654284A1 (en) 2006-05-10
ZA200601206B (en) 2007-05-30
PL1654284T3 (pl) 2009-09-30
CN1867582A (zh) 2006-11-22
US20060194300A1 (en) 2006-08-31
ATE428730T1 (de) 2009-05-15
BRPI0412835A (pt) 2006-09-26
RU2006107533A (ru) 2006-07-27
DE602004020632D1 (de) 2009-05-28
UA86775C2 (ru) 2009-05-25

Similar Documents

Publication Publication Date Title
PL1654284T3 (pl) Sposób uzyskiwania roztworu alfa-1-antytrypsyny
EA200201012A1 (ru) Способы стерилизации биологических материалов
RU95108231A (ru) Glp-1-молекулярный комплекс, фармацевтическая композиция и способ получения комплекса
TW200505480A (en) High concentration antibody and protein formulations
BRPI0412321A (pt) limpeza de membranas de filtração com peróxidos
MEP10408A (en) Platinum derivative pharmaceutical formulations
BRPI0410685B8 (pt) processos de purificação do 1,3-propanodiol e composição
DE50309979D1 (de) Neue purinderivate, deren herstelllung und deren verwendung als arzneimittel
DK1301201T3 (da) Behandling af glycogenosis type II
BR0307236A (pt) Processo para fabricação de compostos orgânicos
PE103799A1 (es) Procedimiento de purificacion de mesilato de alatrofloxacino
WO2004037784A3 (en) Pyrrolidones with anti-hiv activity
EA200300450A1 (ru) Фармацевтические растворы соединений модафинила
BR0107967A (pt) Solução de composto de amÈnio quaternário concentrada e processo para evitar a proliferação de microorganismo em um produto alimentìcio
DE69902816D1 (de) Synthese von heteropolysäuren
EP1831239B8 (en) A process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta -bismethylene-17 alpha-pregn-4-ene-3-one-21-carboxylic acid gamma-lactone and key-intermediates for this process
AR035808A1 (es) Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas
BRPI0407448A (pt) Processo quìmico
BR0311385B1 (pt) oxatinacarboxamidas, seu processo de preparação e seu emprego, agente e seu processo de preparação, bem como processo para o combate de microorganismos indesejados
WO2004037853A3 (en) Quinolones with anti-hiv activity
BRPI0416637A (pt) método para produção de uma solução aquosa de etanolamina de cobre e de uma solução de monoetanolamina de cobre
BRPI0415019A (pt) processo para a purificação da mesotriona
EA200800785A1 (ru) 4-арил-1,4-дигидро-3(2н)-изохинолиноны и 4-арил-1,2,3,4-тетрагидроизохинолины в качестве ингибиторов igf-1r и в качестве фармакологического средства в тест-системах, фармацевтическая композиция и изделие на их основе и способ лечения заболеваний, опосредованных igf-1 рецептором
BRPI0409683A (pt) 5-hidroxiindóis com grupos n-óxido e seu emprego como agentes terapêuticos
SE9904289D0 (sv) Method and camposition for the treatment of adenovairal ocular infections