UA86775C2 - Способ очистки раствора альфа-1-антитрипсина - Google Patents
Способ очистки раствора альфа-1-антитрипсинаInfo
- Publication number
- UA86775C2 UA86775C2 UAA200602563A UAA200602563A UA86775C2 UA 86775 C2 UA86775 C2 UA 86775C2 UA A200602563 A UAA200602563 A UA A200602563A UA A200602563 A UAA200602563 A UA A200602563A UA 86775 C2 UA86775 C2 UA 86775C2
- Authority
- UA
- Ukraine
- Prior art keywords
- preparing
- alpha
- a1at
- detergents
- antitrypsin solution
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 title 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 title 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 title 1
- 239000003599 detergent Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 238000004255 ion exchange chromatography Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49409703P | 2003-08-12 | 2003-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA86775C2 true UA86775C2 (ru) | 2009-05-25 |
Family
ID=34135316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200602563A UA86775C2 (ru) | 2003-08-12 | 2004-08-12 | Способ очистки раствора альфа-1-антитрипсина |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20060194300A1 (enExample) |
| EP (1) | EP1654284B1 (enExample) |
| JP (1) | JP4668904B2 (enExample) |
| KR (1) | KR20060070543A (enExample) |
| CN (1) | CN1867582B (enExample) |
| AT (1) | ATE428730T1 (enExample) |
| AU (1) | AU2004262578B2 (enExample) |
| BR (1) | BRPI0412835A (enExample) |
| CA (1) | CA2534900A1 (enExample) |
| DE (1) | DE602004020632D1 (enExample) |
| DK (1) | DK1654284T3 (enExample) |
| ES (1) | ES2324168T3 (enExample) |
| IL (1) | IL172868A0 (enExample) |
| NO (1) | NO20060109L (enExample) |
| PL (1) | PL1654284T3 (enExample) |
| PT (1) | PT1654284E (enExample) |
| RS (1) | RS20060077A (enExample) |
| RU (1) | RU2370500C2 (enExample) |
| SI (1) | SI1654284T1 (enExample) |
| UA (1) | UA86775C2 (enExample) |
| WO (1) | WO2005014648A1 (enExample) |
| ZA (1) | ZA200601206B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1664123E (pt) * | 2003-09-22 | 2008-07-16 | Kamada Ltd | Preparação em larga escala de um inibidor da alfa-1 proteinase e sua utilização |
| ES2246694B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Nanoparticulas pegiladas. |
| ES2246695B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico. |
| CN100354301C (zh) * | 2005-10-13 | 2007-12-12 | 南京工业大学 | 化学合成多肽的新型大规模分离制备技术 |
| CN100562523C (zh) * | 2006-07-26 | 2009-11-25 | 河北大安制药有限公司 | α1-抗胰蛋白酶的制备方法 |
| ES2611944T3 (es) * | 2007-11-02 | 2017-05-11 | Grifols Therapeutics Inc. | Procedimiento, composición y artículo de fabricación para proporcionar alfa-1-antitripsina |
| CN102127165B (zh) * | 2010-01-15 | 2013-09-04 | 上海莱士血液制品股份有限公司 | 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺 |
| CN102731642B (zh) * | 2011-04-14 | 2014-01-29 | 上海莱士血液制品股份有限公司 | 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺 |
| US9353165B2 (en) * | 2012-07-25 | 2016-05-31 | Grifols, S.A. | Purification of cell culture derived alpha1 protease inhibitor |
| AU2013205138B2 (en) | 2012-08-09 | 2015-06-25 | Grifols, S.A. | Caprylate Viral Deactivation |
| EP3313859B1 (en) | 2015-06-26 | 2019-11-20 | Ferring BV | Methods of purification and/or viral inactivation |
| AU2017214678B2 (en) * | 2016-02-03 | 2024-02-01 | Plasma Technologies, Llc | Methods for extracting proteins from a blood-based material |
| AU2018357917B2 (en) | 2017-10-30 | 2024-08-01 | Takeda Pharmaceutical Company Limited | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| CN111991571B (zh) * | 2020-08-12 | 2022-04-05 | 湖州师范学院 | 一种柱上低pH病毒灭活的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS584728A (ja) * | 1981-05-01 | 1983-01-11 | メデイカル・リサ−チ・インステイチユ−ト・オブ・サンフランシスコ・コ−ポレ−シヨン | α−１−抗トリプシンの精製 |
| US4379087A (en) * | 1982-06-17 | 1983-04-05 | Cutter Laboratories, Inc. | Method of preparing alpha-1-proteinase inhibitor |
| US4684723A (en) * | 1985-09-11 | 1987-08-04 | Miles Laboratories, Inc. | Method of separating proteins from aqueous solutions |
| US4629567A (en) * | 1986-03-07 | 1986-12-16 | Smithkline-Rit | Alpha-1-antiprotease purification |
| ES2053606T3 (es) * | 1987-04-27 | 1994-08-01 | Miles Inc | Metodo de preparacion de un inhibidor de alfa-1-proteinasa de alta pureza. |
| KR920005689B1 (ko) * | 1989-12-21 | 1992-07-13 | 국제약품공업주식회사 | 혈청으로부터 알파-1-안티트립신의 분리 정제 및 혈중 알파-1-안티트립신 양의 검정키트 |
| DE4125625C2 (de) * | 1991-08-02 | 1999-12-02 | Octapharma Ag Glarus | Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen |
| SE9301582D0 (sv) * | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Purification of plasma proteins |
| DE4407837C1 (de) * | 1994-03-09 | 1995-08-17 | Octapharma Ag | Verfahren zur Gewinnung von hochreinem, virusinaktiviertem alpha¶1¶-Antitrypsin mittels Anionenaustauscher-Chromatographie |
| US6284874B1 (en) * | 1994-06-17 | 2001-09-04 | Alpha Therapeutic Corporation | Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste |
| EP1736483A3 (en) * | 1995-09-07 | 2008-07-30 | Pharming Intellectual Property BV | Purification of alpha-1 proteinase inhibitor |
| JP4105249B2 (ja) * | 1996-08-09 | 2008-06-25 | 財団法人化学及血清療法研究所 | α２プラスミンインヒビターの製造方法 |
| AT407114B (de) * | 1997-06-10 | 2000-12-27 | Immuno Ag | Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung |
-
2004
- 2004-08-12 PL PL04764046T patent/PL1654284T3/pl unknown
- 2004-08-12 WO PCT/EP2004/009043 patent/WO2005014648A1/en not_active Ceased
- 2004-08-12 PT PT04764046T patent/PT1654284E/pt unknown
- 2004-08-12 EP EP04764046A patent/EP1654284B1/en not_active Expired - Lifetime
- 2004-08-12 DK DK04764046T patent/DK1654284T3/da active
- 2004-08-12 DE DE602004020632T patent/DE602004020632D1/de not_active Expired - Lifetime
- 2004-08-12 AT AT04764046T patent/ATE428730T1/de active
- 2004-08-12 BR BRPI0412835-4A patent/BRPI0412835A/pt not_active Application Discontinuation
- 2004-08-12 UA UAA200602563A patent/UA86775C2/ru unknown
- 2004-08-12 CN CN2004800208911A patent/CN1867582B/zh not_active Expired - Fee Related
- 2004-08-12 KR KR1020067002718A patent/KR20060070543A/ko not_active Ceased
- 2004-08-12 US US10/566,354 patent/US20060194300A1/en not_active Abandoned
- 2004-08-12 RS YUP-2006/0077A patent/RS20060077A/sr unknown
- 2004-08-12 JP JP2006522987A patent/JP4668904B2/ja not_active Expired - Fee Related
- 2004-08-12 RU RU2006107533/13A patent/RU2370500C2/ru not_active IP Right Cessation
- 2004-08-12 AU AU2004262578A patent/AU2004262578B2/en not_active Ceased
- 2004-08-12 SI SI200431155T patent/SI1654284T1/sl unknown
- 2004-08-12 ES ES04764046T patent/ES2324168T3/es not_active Expired - Lifetime
- 2004-08-12 CA CA002534900A patent/CA2534900A1/en not_active Abandoned
-
2005
- 2005-12-28 IL IL172868A patent/IL172868A0/en unknown
-
2006
- 2006-01-06 NO NO20060109A patent/NO20060109L/no not_active Application Discontinuation
- 2006-02-10 ZA ZA200601206A patent/ZA200601206B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004262578A1 (en) | 2005-02-17 |
| US20060194300A1 (en) | 2006-08-31 |
| JP2007523883A (ja) | 2007-08-23 |
| DE602004020632D1 (de) | 2009-05-28 |
| KR20060070543A (ko) | 2006-06-23 |
| BRPI0412835A (pt) | 2006-09-26 |
| CA2534900A1 (en) | 2005-02-17 |
| DK1654284T3 (da) | 2009-07-20 |
| WO2005014648A1 (en) | 2005-02-17 |
| IL172868A0 (en) | 2006-06-11 |
| PT1654284E (pt) | 2009-07-06 |
| NO20060109L (no) | 2006-02-15 |
| ATE428730T1 (de) | 2009-05-15 |
| CN1867582A (zh) | 2006-11-22 |
| EP1654284A1 (en) | 2006-05-10 |
| RS20060077A (sr) | 2008-08-07 |
| AU2004262578B2 (en) | 2010-05-06 |
| ZA200601206B (en) | 2007-05-30 |
| RU2006107533A (ru) | 2006-07-27 |
| SI1654284T1 (sl) | 2009-10-31 |
| JP4668904B2 (ja) | 2011-04-13 |
| CN1867582B (zh) | 2010-06-16 |
| ES2324168T3 (es) | 2009-07-31 |
| EP1654284B1 (en) | 2009-04-15 |
| RU2370500C2 (ru) | 2009-10-20 |
| PL1654284T3 (pl) | 2009-09-30 |
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