BR0307236A - Processo para fabricação de compostos orgânicos - Google Patents
Processo para fabricação de compostos orgânicosInfo
- Publication number
- BR0307236A BR0307236A BR0307236-3A BR0307236A BR0307236A BR 0307236 A BR0307236 A BR 0307236A BR 0307236 A BR0307236 A BR 0307236A BR 0307236 A BR0307236 A BR 0307236A
- Authority
- BR
- Brazil
- Prior art keywords
- organic compounds
- manufacturing organic
- dihydroxyester
- ketoester
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Abstract
"PROCESSO PARA FABRICAçãO DE COMPOSTOS ORGâNICOS". A presente invenção refere-se a um processo para preparação de um sal de metal alcalino compreendendo: (a) condensação de um dissiloxidieno com um aldeído na presença de um catalisador de titânio (IV) em um solvente inerte para formar um 5(S)-hidróxi-3-cetoéster; (b) redução do 5(S)-hidróxi-3-cetoéster para um 3(R),5(S)-dihidroxiéster na presença de um di(alquil inferior) metoxiborano; e (c) hidrólise de 3(R),5(S)-dihidroxiéster na presença de uma base aquosa para formar um sal de metal alcalino.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35231602P | 2002-01-28 | 2002-01-28 | |
US38318802P | 2002-05-24 | 2002-05-24 | |
PCT/EP2003/000804 WO2003064382A2 (en) | 2002-01-28 | 2003-01-27 | Process for the manufacture of organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0307236A true BR0307236A (pt) | 2004-12-07 |
Family
ID=27669055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0307236-3A BR0307236A (pt) | 2002-01-28 | 2003-01-27 | Processo para fabricação de compostos orgânicos |
Country Status (19)
Country | Link |
---|---|
US (3) | US6835838B2 (pt) |
EP (1) | EP1472227B1 (pt) |
JP (1) | JP2005516064A (pt) |
KR (2) | KR20100091267A (pt) |
CN (2) | CN1625550A (pt) |
AU (4) | AU2003239294B2 (pt) |
BR (1) | BR0307236A (pt) |
CA (1) | CA2472340A1 (pt) |
CO (1) | CO5601045A2 (pt) |
EC (1) | ECSP045202A (pt) |
IL (1) | IL162817A0 (pt) |
MX (1) | MXPA04007308A (pt) |
NO (1) | NO327363B1 (pt) |
NZ (3) | NZ554367A (pt) |
PL (1) | PL371383A1 (pt) |
RU (1) | RU2360903C2 (pt) |
SG (2) | SG157225A1 (pt) |
WO (1) | WO2003064382A2 (pt) |
ZA (1) | ZA200405239B (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1301977C (zh) | 2001-07-13 | 2007-02-28 | 阿斯特拉曾尼卡英国有限公司 | 氨基嘧啶化合物的制备方法 |
KR100919941B1 (ko) * | 2001-11-14 | 2009-10-05 | 닛산 가가쿠 고교 가부시키 가이샤 | 광학활성 옥소헵텐산 에스테르의 제조방법 |
WO2003064392A1 (en) * | 2002-01-31 | 2003-08-07 | Novartis Ag | Process for the manufacture of hmg-coa reductase inhibitors |
WO2004026838A1 (en) * | 2002-09-20 | 2004-04-01 | Nissan Chemical Industries, Ltd. | Method for producing a 3,5-dihydroxy-6-heptenoate |
US20060142582A1 (en) * | 2003-02-12 | 2006-06-29 | Van Der Schaaf Paul A | Crystalline forms of pitavastatin calcium |
US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
TWI328006B (en) | 2003-12-26 | 2010-08-01 | Nissan Chemical Ind Ltd | Crystal form of quinoline compound and process for its production |
CN1763015B (zh) * | 2004-10-22 | 2011-06-22 | 四川抗菌素工业研究所有限公司 | 一种罗舒伐他汀及其药用盐的制备方法及中间体 |
GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
ES2564250T3 (es) * | 2006-05-03 | 2016-03-21 | Msn Laboratories Private Limited | Nuevo proceso para estatinas y sus sales farmacéuticamente aceptables de las mismas |
SI2086945T1 (sl) * | 2006-10-09 | 2016-05-31 | Msn Laboratories Private Limited | Novi postopek za pripravo statinov in njihovih farmacevtsko sprejemljivih soli |
TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
US8487105B2 (en) * | 2009-01-19 | 2013-07-16 | Msn Laboratories Limited | Process for preparing pitavastatin, intermediates and pharmaceuctically acceptable salts thereof |
WO2011086584A2 (en) | 2010-01-18 | 2011-07-21 | Msn Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
EP2423195A1 (en) | 2010-07-26 | 2012-02-29 | LEK Pharmaceuticals d.d. | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof |
JP2013536219A (ja) | 2010-08-25 | 2013-09-19 | カディラ・ヘルスケア・リミテッド | ピタバスタチンカルシウムおよびその調製方法 |
EP3178812A1 (en) * | 2010-11-12 | 2017-06-14 | Hetero Research Foundation | Novel polymorphs of pitavastatin calcium |
WO2012140490A2 (en) | 2011-04-11 | 2012-10-18 | Aurobindo Pharma Limited | Process for preparing quinoline derivative |
CN103755568B (zh) * | 2013-12-10 | 2015-10-28 | 江西科技师范大学 | IeodomycinA和B立体选择性合成方法 |
JP6704916B2 (ja) | 2015-08-05 | 2020-06-03 | 株式会社エーピーアイ コーポレーション | ピタバスタチンカルシウムの製造方法 |
CN108976168B (zh) * | 2017-06-02 | 2020-09-25 | 浙江京新药业股份有限公司 | 一种匹伐他汀半钙盐晶型及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3528186B2 (ja) * | 1991-06-24 | 2004-05-17 | 日産化学工業株式会社 | 光学活性キノリンメバロン酸のジアステレオマー塩 |
JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
JP3554036B2 (ja) * | 1994-09-06 | 2004-08-11 | 宇部興産株式会社 | 光学活性な7−置換キノリル−3,5−ジヒドロキシ−ヘプト−6−エン酸エステル誘導体の製造方法 |
KR100919941B1 (ko) * | 2001-11-14 | 2009-10-05 | 닛산 가가쿠 고교 가부시키 가이샤 | 광학활성 옥소헵텐산 에스테르의 제조방법 |
EP2125754B1 (en) * | 2007-02-08 | 2012-04-11 | Aurobindo Pharma Limited | Process for preparation of rosuvastatin calcium |
-
2003
- 2003-01-24 US US10/350,615 patent/US6835838B2/en not_active Expired - Lifetime
- 2003-01-27 CN CNA038028778A patent/CN1625550A/zh active Pending
- 2003-01-27 SG SG200605092-6A patent/SG157225A1/en unknown
- 2003-01-27 WO PCT/EP2003/000804 patent/WO2003064382A2/en active Application Filing
- 2003-01-27 KR KR1020107017248A patent/KR20100091267A/ko not_active Application Discontinuation
- 2003-01-27 NZ NZ554367A patent/NZ554367A/en not_active IP Right Cessation
- 2003-01-27 PL PL03371383A patent/PL371383A1/xx unknown
- 2003-01-27 JP JP2003564005A patent/JP2005516064A/ja active Pending
- 2003-01-27 AU AU2003239294A patent/AU2003239294B2/en not_active Ceased
- 2003-01-27 NZ NZ554366A patent/NZ554366A/en not_active IP Right Cessation
- 2003-01-27 CA CA002472340A patent/CA2472340A1/en not_active Abandoned
- 2003-01-27 NZ NZ534136A patent/NZ534136A/en not_active IP Right Cessation
- 2003-01-27 MX MXPA04007308A patent/MXPA04007308A/es active IP Right Grant
- 2003-01-27 EP EP03734696.2A patent/EP1472227B1/en not_active Expired - Lifetime
- 2003-01-27 CN CNB200510005170XA patent/CN100378081C/zh not_active Expired - Lifetime
- 2003-01-27 KR KR10-2004-7011572A patent/KR20040077883A/ko active Search and Examination
- 2003-01-27 IL IL16281703A patent/IL162817A0/xx unknown
- 2003-01-27 BR BR0307236-3A patent/BR0307236A/pt not_active Application Discontinuation
- 2003-01-27 RU RU2004126448/04A patent/RU2360903C2/ru not_active IP Right Cessation
- 2003-01-27 SG SG200605094-2A patent/SG161742A1/en unknown
-
2004
- 2004-07-01 ZA ZA2004/05239A patent/ZA200405239B/en unknown
- 2004-07-14 US US10/891,357 patent/US7572917B2/en not_active Expired - Fee Related
- 2004-07-22 EC EC2004005202A patent/ECSP045202A/es unknown
- 2004-08-06 CO CO04076720A patent/CO5601045A2/es not_active Application Discontinuation
- 2004-08-27 NO NO20043586A patent/NO327363B1/no not_active IP Right Cessation
-
2006
- 2006-10-03 AU AU2006225205A patent/AU2006225205B2/en not_active Ceased
- 2006-10-03 AU AU2006225206A patent/AU2006225206B2/en not_active Ceased
-
2009
- 2009-07-02 US US12/497,001 patent/US20090299065A1/en not_active Abandoned
- 2009-08-12 AU AU2009208129A patent/AU2009208129A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0307236A (pt) | Processo para fabricação de compostos orgânicos | |
BRPI0407967A (pt) | processo de uma etapa para a preparação de derivados anticonvulsivantes | |
EA200300211A1 (ru) | Азабициклические соединения, способ их получения и их применение в качестве лекарственных средств, в частности в качестве антибактериальных средств | |
BR0112693A (pt) | (derivados) de ácido sulfonilaminometilbenzóico substituìdos e processo para preparação do mesmo | |
BR0112538A (pt) | Sais estáveis de ácido o-acetilsalicìlico com aminoácidos básicos | |
NI200500164A (es) | Nueva difenilazetidinona con caracteristicas fisiologicas mejoradas, correspondiente metodo de produccion, medicamentos que contienen dicho compuesto y su uso. | |
BR0012212A (pt) | Processo de hidrogenação de 3-hidroxipropanal em 1,3-propanodiol, processo de preparação de 1,3-propanodiol, processo de purificação de uma solução aquosa de 3-hidroxipropanal e composição de 1,3-propanodiol | |
BRPI0416534A (pt) | composições multiparticuladas com estabilidade melhorada | |
TW200716582A (en) | Process for making a pharmaceutical compound | |
BRPI0507979A (pt) | processo para preparação de um composto | |
BR0215097A (pt) | Processo para fazer o composto da fórmula e composto da fórmula | |
BR0301667A (pt) | Processo para a preparação de polìmeros em emulsão com pureza elevada | |
BR0208861A (pt) | Processo para a preparação de um composto, e, composto | |
BR9808854A (pt) | Processo para preparação de um composto, e, composto | |
BR0011996A (pt) | Preparação de piperidin-4-onas substituìdas | |
BR0108990A (pt) | Processo para preparação de derivados de pirimidona com atividade antifungos | |
BR0212390A (pt) | Processo para a preparação de cilastatina | |
NO20040388L (no) | Fremgangsmåte for fremstilling av beraprost og salter derav, samt forbindelser som er mellomprodukter i fremgangsmåten | |
DE602004020632D1 (de) | Verfahren zur herstellung einer alpha-1-antitrypsinlösung | |
BR0311699A (pt) | Processo para a decomposição de hidroperóxido de cicloexila | |
BRPI0409235A (pt) | processo para a produção de sal de amÈnio do ácido 2-hidróxi-4-metiltiobutìrico | |
BRPI0411652A (pt) | processo para a preparação de derivados de espirobenzoazepina substituìdos não-peptìdicos | |
BRPI0407448A (pt) | Processo quìmico | |
BR0314306A (pt) | Processo para produção de um álcool pela hidrogenação de um aldeìdo alifático sobre um catalisador | |
BR0214971A (pt) | Processo para a produção de um imunossupressor |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |