EA200201012A1 - Способы стерилизации биологических материалов - Google Patents

Способы стерилизации биологических материалов

Info

Publication number
EA200201012A1
EA200201012A1 EA200201012A EA200201012A EA200201012A1 EA 200201012 A1 EA200201012 A1 EA 200201012A1 EA 200201012 A EA200201012 A EA 200201012A EA 200201012 A EA200201012 A EA 200201012A EA 200201012 A1 EA200201012 A1 EA 200201012A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
sterilization
biological materials
mycoplasma
parasites
Prior art date
Application number
EA200201012A
Other languages
English (en)
Other versions
EA005977B1 (ru
Inventor
Рендэлл С. Кент
Эдвард А. Хортон
Original Assignee
Клиарант, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Клиарант, Инк. filed Critical Клиарант, Инк.
Publication of EA200201012A1 publication Critical patent/EA200201012A1/ru
Publication of EA005977B1 publication Critical patent/EA005977B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0041—X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0047—Ultraviolet radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0052—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/007—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0058—Infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/22—Blood or products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation

Abstract

Способы предназначены для стерилизации биологических продуктов путем снижения уровня активных биологических примесей, таких как вирусы, бактерии, дрожжи, грибы, микоплазма и паразиты.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200201012A 2000-03-23 2001-03-23 Способы стерилизации биологических материалов EA005977B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53354700A 2000-03-23 2000-03-23
PCT/US2001/009361 WO2001070279A1 (en) 2000-03-23 2001-03-23 Methods for sterilizing biological materials

Publications (2)

Publication Number Publication Date
EA200201012A1 true EA200201012A1 (ru) 2003-06-26
EA005977B1 EA005977B1 (ru) 2005-08-25

Family

ID=24126435

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200201012A EA005977B1 (ru) 2000-03-23 2001-03-23 Способы стерилизации биологических материалов

Country Status (15)

Country Link
US (1) US20030143106A1 (ru)
EP (2) EP1762251A1 (ru)
JP (1) JP2003527210A (ru)
KR (1) KR20030011279A (ru)
CN (1) CN1427729A (ru)
AU (2) AU5903101A (ru)
BR (1) BR0109764A (ru)
CA (1) CA2403834A1 (ru)
EA (1) EA005977B1 (ru)
IL (1) IL151881A0 (ru)
MX (1) MXPA02009321A (ru)
NZ (1) NZ521392A (ru)
PL (1) PL197667B1 (ru)
WO (1) WO2001070279A1 (ru)
ZA (1) ZA200208120B (ru)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090297602A1 (en) * 1998-11-02 2009-12-03 Devane John G Modified Release Loxoprofen Compositions
PT1126826E (pt) 1998-11-02 2008-11-25 Elan Pharma Int Ltd Composição de metilfenidato de libertação modificada multiparticulada
WO2001087357A2 (en) * 2000-05-17 2001-11-22 The American National Red Cross Gamma irradiation of protein-based pharmaceutical products
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
WO2003066110A1 (en) * 2002-02-01 2003-08-14 Gambro, Inc. Pathogen reduction solution for platelets containing an endogenous photosensitizer and a glycolysis inhibitor.
ATE477810T1 (de) * 2002-02-28 2010-09-15 Nipro Corp Stabilisierte albumin-zubereitungen
KR100458965B1 (ko) * 2002-03-05 2004-12-03 충남대학교산학협력단 저선량 감마선조사 처리를 이용한 소, 돼지 혈분의 제조방법
US20040029097A1 (en) * 2002-04-16 2004-02-12 Gambro, Inc. Addition of glycolysis inhibitor to a pathogen reduction and storage solution
WO2004032980A1 (en) * 2002-10-04 2004-04-22 Elan Pharma International Limited Gamma irradiation of solid nanoparticulate active agents
JP2007501683A (ja) * 2003-05-22 2007-02-01 エラン ファーマ インターナショナル リミテッド γ線照射によるナノ粒子活性物質分散体の滅菌法
WO2006096462A1 (en) * 2005-03-03 2006-09-14 Elan Pharma International Limited Nanoparticulate compositions of heterocyclic amide derivatives
EP1767225A1 (en) * 2005-09-21 2007-03-28 Insense Limited Method for stabilisation of a protein solution by addition of hydroxyl radical quenchers and its sterilisation by ionising radiation
JP2007248175A (ja) * 2006-03-15 2007-09-27 Sekisui Chem Co Ltd 血液検査用容器
BRPI0714173A2 (pt) * 2006-07-12 2012-12-25 Elan Pharma Int Ltd composiÇço nanoparticulada estÁvel,mÉtodos para preparar a composiÇço, para prevenir e/ou tratar estados de doenÇas, sintomas, sÍndromes e condiÇÕes do sistema nervoso central, para melhorar ou manter a biodisponibilidade de modafinil, e para tratar distérbio com base neurolàgica, composiÇço farmacÊutica, e forma de dosagem
US10232064B2 (en) 2006-10-04 2019-03-19 National Cheng Kung University Method for sterilizing biological materials
US8580192B2 (en) 2006-10-31 2013-11-12 Ethicon, Inc. Sterilization of polymeric materials
GB0626021D0 (en) 2006-12-29 2007-02-07 Insense Ltd The stabilisation of proteins
US7704453B2 (en) * 2007-06-07 2010-04-27 Ethicon, Inc. Method for establishing a sterilizing dose for radiation sensitive products
KR100873395B1 (ko) * 2007-06-26 2008-12-11 한국원자력연구원 비타민 씨의 첨가공정을 이용한 방사선 조사방법
CA2721986C (en) * 2008-04-24 2017-03-14 Medtronic, Inc. Rehydratable polysaccharide particles and sponge
CN101757651B (zh) * 2008-11-18 2013-09-25 上海松力生物技术有限公司 一种动物纤维蛋白原病毒灭活方法
CN101757616B (zh) * 2008-11-18 2012-10-31 上海松力生物技术有限公司 一种安全的冻干哺乳动物源凝血酶制剂及其制备方法
EP2236617A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
KR101163736B1 (ko) 2010-01-11 2012-07-09 한스바이오메드 주식회사 피부조직 가공물의 멸균방법
CN102240407B (zh) * 2010-05-13 2013-08-07 上海佩尼医疗科技发展有限公司 一种用于血液净化产品的电子束灭菌方法
KR101322712B1 (ko) * 2011-09-01 2013-10-28 한국원자력연구원 에탄올 및 방사선 조사의 병용 처리를 이용한 절화 화훼류의 위생화 방법
AU2012314515B2 (en) 2011-09-26 2018-03-15 Preanalytix Gmbh Stabilisation and isolation of extracellular nucleic acids
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
KR102091294B1 (ko) * 2011-10-26 2020-04-16 암젠 인크 Uv 광으로의 노출로 인한 단백질 변형 및 분해의 감소 또는 제거 방법
ES2614247T3 (es) 2012-09-25 2017-05-30 Qiagen Gmbh Estabilización de muestras biológicas
EP2976424B1 (en) 2013-03-18 2018-10-03 Qiagen GmbH Stabilisation of biological samples
CN105121643A (zh) 2013-03-18 2015-12-02 凯杰有限公司 细胞外核酸的稳定化和分离
EP3269725A4 (en) 2015-03-12 2018-11-07 Sanyo Chemical Industries, Ltd. Method for producing protein composition, and protein composition
FR3036707B1 (fr) 2015-05-29 2019-05-17 Maco Pharma Procede de sterilisation d'un lysat plaquettaire
US10213521B2 (en) * 2015-06-11 2019-02-26 Medtronic Xomed, Inc. Useful polysaccharide after radiation sterilization
CN108291250B (zh) * 2015-11-20 2022-05-27 凯杰有限公司 用于稳定细胞外核酸的已灭菌组合物的制备方法
CN105521521B (zh) * 2015-12-17 2018-10-30 杭州亚慧生物科技有限公司 一种肺部封合医用凝胶及其制备方法与应用
CN105497925B (zh) * 2015-12-25 2019-02-26 烟台正海生物科技股份有限公司 一种在电离辐射灭菌前对功能蛋白进行保护的方法及其专用保护剂
US11090411B2 (en) * 2016-01-28 2021-08-17 Warsaw Orthopedic, Inc. Electron beam irradiated osteoinductive bone implant
AU2019269671A1 (en) * 2018-05-18 2020-10-22 Qiagen Sciences Llc Protection of biologically active molecules during radiation sterilization
EP3633028A1 (en) * 2018-10-02 2020-04-08 PL BioScience GmbH Method for producing a virus-free platelet lysate material
CN111154710A (zh) * 2020-03-06 2020-05-15 兰州荣晔生物科技有限责任公司 一种牛血清冷冻高剂量辐照方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962038A (en) * 1972-03-09 1976-06-08 Director Of National Food Research Institute Preparation of water-insoluble enzymes
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4620908A (en) * 1983-10-03 1986-11-04 Biocell Laboratories, Inc. Method for destroying microbial contamination in protein materials
US4894253A (en) * 1986-08-12 1990-01-16 University Of Cincinnati Method for production of coated electrode
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
ES2054641T3 (es) * 1987-09-30 1994-08-16 Mucos Emulsions Gmbh Utilizacion de enzimas catabolicas para la preparacion de un medicamento destinado a combatir la inmunodeficiencia adquirida (sida) y sus etapas previas (sla y crs).
US4994237A (en) * 1987-10-02 1991-02-19 The Beth Israel Hospital Association Microwave preservation of bioprostheses
US5643464A (en) * 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
EP0424159A3 (en) * 1989-10-19 1991-11-06 Osteotech, Inc., Aseptic processing of allograft bone and tissue
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5712086A (en) * 1990-05-15 1998-01-27 New York Blood Center, Inc. Process for transfusing cell containing fractions sterilized with radiation and a quencher of type I and type II photodynamic reactions
US5981163A (en) * 1990-05-15 1999-11-09 New York Blood Center, Inc. Process for the sterilization of biological compositions using irradiation and quenchers of type I and type II photodynamic reactions
US5618662A (en) * 1992-03-02 1997-04-08 Cerus Corporation Intravenous administration of psoralen
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US5383732A (en) * 1993-12-20 1995-01-24 Pitney Bowes Inc. Thermal printing postage dispensing device having security features and method of using
US6203755B1 (en) * 1994-03-04 2001-03-20 St. Jude Medical, Inc. Electron beam sterilization of biological tissues
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US5730933A (en) * 1996-04-16 1998-03-24 Depuy Orthopaedics, Inc. Radiation sterilization of biologically active compounds
SK71399A3 (en) * 1996-12-10 2000-05-16 Purdue Research Foundation Tubular submucosal graft constructs
JP4046358B2 (ja) * 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
DE69814070T2 (de) * 1997-02-10 2003-12-18 Biomedical Design Inc Sterilisationsverfahren
US6383810B2 (en) * 1997-02-14 2002-05-07 Invitrogen Corporation Dry powder cells and cell culture reagents and methods of production thereof
US5958669A (en) * 1997-05-02 1999-09-28 St. Jude Medical, Inc. Apparatus and method for crosslinking to fix tissue or crosslink molecules to tissue
US6157028A (en) * 1998-05-28 2000-12-05 Jrh Biosciences, Inc. Method for dose mapping to ensure proper amounts of gamma irradiation
US6312931B1 (en) * 2000-02-11 2001-11-06 Purepulse Technologies, Inc. Protecting molecules in biologically derived compositions while treating with high intensity broad-spectrum pulsed light

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EP1299131A4 (en) 2003-06-18
BR0109764A (pt) 2003-07-01
US20030143106A1 (en) 2003-07-31
WO2001070279A1 (en) 2001-09-27
ZA200208120B (en) 2003-05-14
CA2403834A1 (en) 2001-09-27
AU2001259031B2 (en) 2006-04-13
AU5903101A (en) 2001-10-03
EA005977B1 (ru) 2005-08-25
CN1427729A (zh) 2003-07-02
IL151881A0 (en) 2003-04-10
EP1762251A1 (en) 2007-03-14
NZ521392A (en) 2004-06-25
JP2003527210A (ja) 2003-09-16
PL358451A1 (en) 2004-08-09
MXPA02009321A (es) 2003-05-23
EP1299131A1 (en) 2003-04-09
KR20030011279A (ko) 2003-02-07
PL197667B1 (pl) 2008-04-30

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