PT1326832E - Compostos quimicos - Google Patents
Compostos quimicosInfo
- Publication number
- PT1326832E PT1326832E PT01976453T PT01976453T PT1326832E PT 1326832 E PT1326832 E PT 1326832E PT 01976453 T PT01976453 T PT 01976453T PT 01976453 T PT01976453 T PT 01976453T PT 1326832 E PT1326832 E PT 1326832E
- Authority
- PT
- Portugal
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0025354.2A GB0025354D0 (en) | 2000-10-17 | 2000-10-17 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1326832E true PT1326832E (pt) | 2005-01-31 |
Family
ID=9901397
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01976453T PT1326832E (pt) | 2000-10-17 | 2001-10-12 | Compostos quimicos |
PT04077714T PT1524266E (pt) | 2000-10-17 | 2001-10-12 | Composição farmacêutica. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT04077714T PT1524266E (pt) | 2000-10-17 | 2001-10-12 | Composição farmacêutica. |
Country Status (29)
Country | Link |
---|---|
US (5) | US7119092B2 (pt) |
EP (4) | EP1524266B1 (pt) |
JP (1) | JP3940359B2 (pt) |
KR (1) | KR100847414B1 (pt) |
CN (1) | CN1231468C (pt) |
AR (1) | AR034268A1 (pt) |
AT (3) | ATE355271T1 (pt) |
AU (4) | AU9572301A (pt) |
BR (1) | BR0114637A (pt) |
CA (1) | CA2425876C (pt) |
CY (1) | CY1107634T1 (pt) |
CZ (1) | CZ299824B6 (pt) |
DE (3) | DE60127002T2 (pt) |
DK (2) | DK1524266T3 (pt) |
ES (3) | ES2346108T3 (pt) |
GB (1) | GB0025354D0 (pt) |
HK (2) | HK1058788A1 (pt) |
HU (1) | HU228146B1 (pt) |
IL (3) | IL155165A0 (pt) |
MX (1) | MXPA03003536A (pt) |
MY (1) | MY124957A (pt) |
NO (1) | NO324468B1 (pt) |
NZ (1) | NZ525091A (pt) |
PL (1) | PL203071B1 (pt) |
PT (2) | PT1326832E (pt) |
SI (2) | SI1524266T1 (pt) |
TW (1) | TWI299730B (pt) |
WO (1) | WO2002032867A1 (pt) |
ZA (1) | ZA200302801B (pt) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE39921E1 (en) | 1999-10-07 | 2007-11-13 | Smithkline Beecham Corporation | Chemical compounds |
GB9923748D0 (en) | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
GB0025354D0 (en) | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
GB0108595D0 (en) | 2001-04-05 | 2001-05-23 | Glaxo Group Ltd | Chemical compounds |
GB0119797D0 (en) | 2001-08-14 | 2001-10-03 | Glaxo Group Ltd | Chemical compounds |
GB0203022D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
GB0203020D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
US7482365B2 (en) | 2002-02-08 | 2009-01-27 | Glaxo Group Limited | Piperidylcarboxamide derivatives and their use in the treatment of tachykinin-mediated diseases |
TWI283241B (en) | 2002-05-29 | 2007-07-01 | Tanabe Seiyaku Co | Novel piperidine compound |
JP4079727B2 (ja) * | 2002-09-06 | 2008-04-23 | セントラル硝子株式会社 | 光学活性1−(フルオロ、トリフルオロメチルまたはトリフルオロメトキシ置換フェニル)アルキルアミンn−モノアルキル誘導体とその製造方法 |
EP1578744B1 (en) * | 2002-12-23 | 2008-07-09 | Janssen Pharmaceutica N.V. | Substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives and their use as neurokinin antagonists |
CA2509406C (en) * | 2002-12-23 | 2012-07-03 | Janssen Pharmaceutica N.V. | Substituted 1-piperidin-4-yl-4-azetidin-3-yl-piperazine derivatives and their use as neurokinin antagonists |
JO2696B1 (en) | 2002-12-23 | 2013-03-03 | شركة جانسين فارماسوتيكا ان. في | Derivatives of 1-piperdine-4-yl-4-biprolidine-3-yl-piperazine substituted and used as quinine antagonists |
JO2485B1 (en) * | 2002-12-23 | 2009-01-20 | شركة جانسين فارماسوتيكا ان. في | 1-Piperidine-3-Yl-4-Piperidine-4-Yl-Piperazine derivatives substituted and used as quinine antagonists |
EP1594574A2 (en) * | 2003-01-27 | 2005-11-16 | Glaxo Group Limited | Nk1 receptor antagonists for the treatment of functional dyspepsia |
FR2853648B1 (fr) * | 2003-04-11 | 2006-08-18 | Fournier Lab Sa | Nouveaux derives de benzenesulfonamides et leur utilisation en therapeutique |
US20040242639A1 (en) * | 2003-03-31 | 2004-12-02 | Bharat Lagu | Phospholipase C inhibitors for use in treating inflammatory disorders |
US7262197B2 (en) | 2003-03-31 | 2007-08-28 | Janssen Pharmaceutica, N.V | Phospholipase C inhibitors for use in treating inflammatory disorders |
US20040235855A1 (en) * | 2003-03-31 | 2004-11-25 | Bharat Lagu | Phospholipase C inhibitors for use in treating inflammatory disorders |
GB0308968D0 (en) * | 2003-04-17 | 2003-05-28 | Glaxo Group Ltd | Medicaments |
ATE395062T1 (de) * | 2003-06-10 | 2008-05-15 | Janssen Pharmaceutica Nv | Kombination von opioiden und einem piperazin- derivat für die behandlung von schmerzen |
EP1638935A1 (en) * | 2003-06-19 | 2006-03-29 | Pfizer Products Inc. | Nk1 antagonist |
JO2525B1 (en) * | 2004-04-08 | 2010-03-17 | شركة جانسين فارماسوتيكا ان. في | Derived 4-alkyl-and-4-canoelperidine derivatives and their use as anti-neroquin |
WO2006062110A1 (ja) * | 2004-12-06 | 2006-06-15 | Banyu Pharmaceutical Co., Ltd. | ピペラジン誘導体 |
GB0426942D0 (en) * | 2004-12-08 | 2005-01-12 | Glaxo Group Ltd | Medicament |
CA2599186C (en) | 2005-03-08 | 2014-12-09 | Janssen Pharmaceutica N.V. | Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists |
GB0514707D0 (en) * | 2005-07-18 | 2005-08-24 | Glaxo Group Ltd | Chemical compounds |
GB0514705D0 (en) * | 2005-07-18 | 2005-08-24 | Glaxo Group Ltd | Chemical compounds |
GB0514704D0 (en) * | 2005-07-18 | 2005-08-24 | Glaxo Group Ltd | Chemical compounds |
JP4904945B2 (ja) | 2006-06-30 | 2012-03-28 | セントラル硝子株式会社 | 光学活性1−(フルオロ、トリフルオロメチルまたはトリフルオロメトキシ置換フェニル)アルキルアミンn−モノアルキル誘導体の製造方法 |
EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
CA2698808A1 (en) | 2007-09-13 | 2009-03-19 | Concert Pharmaceuticals, Inc. | Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof |
GB0812849D0 (en) * | 2008-07-14 | 2008-08-20 | Glaxo Wellcome Mfg Pte Ltd | Novel compounds |
WO2013004766A1 (en) | 2011-07-04 | 2013-01-10 | Ferrari Giulio | Nk-1 receptor antagonists for treating corneal neovascularisation |
US9181259B2 (en) | 2012-02-22 | 2015-11-10 | Leo Pharma A/S | Substituted pyrrolo[1,2-a]piperazines and pyrrolo[1,2-a][1,4]diazepines as neurokinin 1 receptor antagonists |
WO2015024203A1 (en) | 2013-08-20 | 2015-02-26 | Leo Pharma A/S | Novel neurokinin 1 receptor antagonist compounds ii |
BR112019021125A2 (pt) | 2017-04-10 | 2020-05-12 | Chase Therapeutics Corporation | Combinação de antagonista de nk1 e método para tratamento de sinucleinopatias |
EA202090180A1 (ru) | 2017-06-30 | 2020-05-26 | Чейс Терапьютикс Корпорейшн | Композиции nk1-антагониста и способы лечения депрессии |
CN111116514B (zh) * | 2020-01-10 | 2024-03-19 | 广州科锐特生物科技有限公司 | 一种1-环丙甲酰基哌嗪盐酸盐的制备方法 |
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GB0025354D0 (en) * | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
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GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
MY141736A (en) | 2002-10-08 | 2010-06-15 | Elanco Animal Health Ireland | Substituted 1,4-di-piperidin-4-yi-piperazine derivatives and their use as neurokinin antagonists |
-
2000
- 2000-10-17 GB GBGB0025354.2A patent/GB0025354D0/en not_active Ceased
-
2001
- 2001-10-12 CA CA002425876A patent/CA2425876C/en not_active Expired - Fee Related
- 2001-10-12 CZ CZ20031082A patent/CZ299824B6/cs not_active IP Right Cessation
- 2001-10-12 AT AT04077714T patent/ATE355271T1/de active
- 2001-10-12 BR BR0114637-8A patent/BR0114637A/pt not_active Application Discontinuation
- 2001-10-12 EP EP04077714A patent/EP1524266B1/en not_active Expired - Lifetime
- 2001-10-12 KR KR1020037005286A patent/KR100847414B1/ko not_active IP Right Cessation
- 2001-10-12 DE DE60127002T patent/DE60127002T2/de not_active Expired - Lifetime
- 2001-10-12 PL PL361180A patent/PL203071B1/pl unknown
- 2001-10-12 JP JP2002536051A patent/JP3940359B2/ja not_active Expired - Fee Related
- 2001-10-12 AU AU9572301A patent/AU9572301A/xx active Pending
- 2001-10-12 EP EP08151841A patent/EP1921064B1/en not_active Expired - Lifetime
- 2001-10-12 MX MXPA03003536A patent/MXPA03003536A/es active IP Right Grant
- 2001-10-12 ES ES08151841T patent/ES2346108T3/es not_active Expired - Lifetime
- 2001-10-12 NZ NZ525091A patent/NZ525091A/en not_active IP Right Cessation
- 2001-10-12 PT PT01976453T patent/PT1326832E/pt unknown
- 2001-10-12 DE DE60106287T patent/DE60106287T2/de not_active Expired - Lifetime
- 2001-10-12 AT AT08151841T patent/ATE468324T1/de not_active IP Right Cessation
- 2001-10-12 AT AT01976453T patent/ATE278669T1/de active
- 2001-10-12 CN CNB018175325A patent/CN1231468C/zh not_active Expired - Fee Related
- 2001-10-12 DK DK04077714T patent/DK1524266T3/da active
- 2001-10-12 DE DE60142197T patent/DE60142197D1/de not_active Expired - Lifetime
- 2001-10-12 US US10/398,264 patent/US7119092B2/en not_active Expired - Fee Related
- 2001-10-12 DK DK01976453T patent/DK1326832T3/da active
- 2001-10-12 HU HU0301459A patent/HU228146B1/hu not_active IP Right Cessation
- 2001-10-12 IL IL15516501A patent/IL155165A0/xx active IP Right Grant
- 2001-10-12 ES ES04077714T patent/ES2282794T3/es not_active Expired - Lifetime
- 2001-10-12 SI SI200130727T patent/SI1524266T1/sl unknown
- 2001-10-12 SI SI200130206T patent/SI1326832T1/xx unknown
- 2001-10-12 WO PCT/GB2001/004580 patent/WO2002032867A1/en active Application Filing
- 2001-10-12 ES ES01976453T patent/ES2227287T3/es not_active Expired - Lifetime
- 2001-10-12 AU AU2001295723A patent/AU2001295723B2/en not_active Ceased
- 2001-10-12 PT PT04077714T patent/PT1524266E/pt unknown
- 2001-10-12 EP EP01976453A patent/EP1326832B1/en not_active Expired - Lifetime
- 2001-10-12 EP EP06122021A patent/EP1752449A1/en not_active Withdrawn
- 2001-10-15 AR ARP010104833A patent/AR034268A1/es not_active Application Discontinuation
- 2001-10-15 MY MYPI20014779A patent/MY124957A/en unknown
- 2001-10-15 TW TW090125397A patent/TWI299730B/zh not_active IP Right Cessation
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2003
- 2003-03-31 IL IL155165A patent/IL155165A/en not_active IP Right Cessation
- 2003-04-07 NO NO20031561A patent/NO324468B1/no not_active IP Right Cessation
- 2003-04-10 ZA ZA200302801A patent/ZA200302801B/en unknown
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2004
- 2004-01-13 HK HK04100241A patent/HK1058788A1/xx not_active IP Right Cessation
- 2004-11-22 US US10/994,605 patent/US7060702B2/en not_active Expired - Lifetime
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2005
- 2005-05-23 HK HK05104289A patent/HK1075889A1/xx not_active IP Right Cessation
- 2005-08-24 AU AU2005204234A patent/AU2005204234B2/en not_active Ceased
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2006
- 2006-02-21 US US11/358,631 patent/US7294630B2/en not_active Expired - Fee Related
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2007
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- 2007-10-01 US US11/865,211 patent/US7648990B2/en not_active Expired - Fee Related
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2008
- 2008-05-15 IL IL191486A patent/IL191486A0/en unknown
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2009
- 2009-04-09 AU AU2009201407A patent/AU2009201407B2/en not_active Ceased
- 2009-12-03 US US12/630,037 patent/US20100081667A1/en not_active Abandoned
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