PT1149090E - Nova forma cristalina do sal de potassio de (s)-omeprazole - Google Patents
Nova forma cristalina do sal de potassio de (s)-omeprazoleInfo
- Publication number
- PT1149090E PT1149090E PT00903058T PT00903058T PT1149090E PT 1149090 E PT1149090 E PT 1149090E PT 00903058 T PT00903058 T PT 00903058T PT 00903058 T PT00903058 T PT 00903058T PT 1149090 E PT1149090 E PT 1149090E
- Authority
- PT
- Portugal
- Prior art keywords
- crystaline
- omeprazole
- new
- salt form
- potassium salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9900274A SE9900274D0 (sv) | 1999-01-28 | 1999-01-28 | New compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1149090E true PT1149090E (pt) | 2003-07-31 |
Family
ID=20414267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00903058T PT1149090E (pt) | 1999-01-28 | 2000-01-18 | Nova forma cristalina do sal de potassio de (s)-omeprazole |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US6511996B1 (pt) |
| EP (1) | EP1149090B1 (pt) |
| JP (1) | JP2002535401A (pt) |
| KR (1) | KR100624054B1 (pt) |
| CN (1) | CN1231477C (pt) |
| AR (1) | AR022425A1 (pt) |
| AT (1) | ATE236899T1 (pt) |
| AU (1) | AU768676B2 (pt) |
| BG (1) | BG65060B1 (pt) |
| BR (1) | BR0007647A (pt) |
| CA (1) | CA2357744C (pt) |
| CZ (1) | CZ300504B6 (pt) |
| DE (1) | DE60002042T2 (pt) |
| DK (1) | DK1149090T3 (pt) |
| DZ (1) | DZ3001A1 (pt) |
| EE (1) | EE04240B1 (pt) |
| EG (1) | EG23980A (pt) |
| ES (1) | ES2193937T3 (pt) |
| HK (1) | HK1041259B (pt) |
| HU (1) | HU226766B1 (pt) |
| ID (1) | ID30095A (pt) |
| IL (1) | IL144107A0 (pt) |
| IS (1) | IS2019B (pt) |
| MY (1) | MY119095A (pt) |
| NO (1) | NO319719B1 (pt) |
| NZ (1) | NZ512804A (pt) |
| PL (1) | PL197881B1 (pt) |
| PT (1) | PT1149090E (pt) |
| RS (1) | RS50200B (pt) |
| RU (1) | RU2237666C2 (pt) |
| SA (1) | SA00200895B1 (pt) |
| SE (1) | SE9900274D0 (pt) |
| SI (1) | SI1149090T1 (pt) |
| SK (1) | SK285626B6 (pt) |
| TN (1) | TNSN00017A1 (pt) |
| TR (1) | TR200102138T2 (pt) |
| TW (1) | TWI269795B (pt) |
| UA (1) | UA71594C2 (pt) |
| WO (1) | WO2000044744A1 (pt) |
| ZA (1) | ZA200105526B (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875872B1 (en) * | 1993-05-28 | 2005-04-05 | Astrazeneca | Compounds |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| WO2004099181A1 (en) * | 2003-05-05 | 2004-11-18 | Ranbaxy Laboratories Limited | Barium salt of benzimidazole derivative |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| CA2561700A1 (en) * | 2004-04-16 | 2005-12-15 | Santarus, Inc. | Combination of proton pump inhibitor, buffering agent, and prokinetic agent |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| CA2570795C (en) * | 2004-06-24 | 2013-05-28 | Astrazeneca Ab | Process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt |
| WO2006073779A1 (en) * | 2004-12-30 | 2006-07-13 | Transform Phamaceuticals, Inc. | Novel omeprazole forms and related methods |
| ES2259269B1 (es) | 2005-03-03 | 2007-11-01 | Esteve Quimica, S.A. | Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos. |
| US7576219B2 (en) | 2005-10-26 | 2009-08-18 | Hanmi Pharm. Co., Ltd | Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same |
| EP1801110A1 (en) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Esomeprazole arginine salt |
| CN100384839C (zh) * | 2006-02-17 | 2008-04-30 | 中国科学院上海有机化学研究所 | [(取代的吡啶基)甲基]亚磺酰基-1h-苯并咪唑类化合物及其对映体的锌盐的制备方法 |
| EP2040710A2 (en) * | 2006-06-21 | 2009-04-01 | Glenmark Pharmaceuticals Limited | Novel polymorph of esomeprazole potassium and process for its preparation |
| EP2068841B1 (en) | 2006-10-05 | 2018-09-26 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
| EP2486910A3 (en) | 2006-10-27 | 2012-08-22 | The Curators Of The University Of Missouri | Multi-chambered apparatus comprising a dispenser head |
| CL2007003468A1 (es) | 2006-12-04 | 2008-07-04 | Bayer Schering Pharma Ag | Sal de potasio cristalina de analogos de lipoxina a4; metodode sintesis; composicion farmaceutica; y uso en el tratamiento de trastornos inflamatorios o autoinmunes. |
| FR2920428B1 (fr) * | 2007-08-29 | 2012-06-15 | Univ Rouen | Procede de dedoublement de sels de l'omeprazole |
| WO2009074997A2 (en) * | 2007-12-10 | 2009-06-18 | Lee Pharma Ltd. | A novel process for the preparation of crystalline magnesium salt of (s)-omeprazole di hydrate |
| EP2143722A1 (en) | 2008-07-09 | 2010-01-13 | Lek Pharmaceuticals D.D. | Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium |
| WO2010097583A1 (en) | 2009-02-24 | 2010-09-02 | Cipla Limited | Esomeprazole potassium polymorph and its preparation |
| WO2010122583A2 (en) | 2009-04-24 | 2010-10-28 | Rubicon Research Private Limited | Oral pharmaceutical compositions of acid labile substances |
| SG181535A1 (en) | 2009-12-08 | 2012-07-30 | Codexis Inc | Synthesis of prazole compounds |
| CN102319223B (zh) * | 2011-09-21 | 2013-06-19 | 石药集团欧意药业有限公司 | 一种埃索美拉唑冻干制剂及其制备方法 |
| CN102633776B (zh) * | 2012-03-28 | 2014-06-18 | 中山市仁合药业有限公司 | 一种埃索美拉唑及其钠盐的制备方法 |
| WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| GB2189698A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| US5877192A (en) | 1993-05-28 | 1999-03-02 | Astra Aktiebolag | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
| DK0723436T3 (da) | 1994-07-08 | 2001-11-26 | Astrazeneca Ab | Tabletteret flerenhedsdoseringsform |
| SE504459C2 (sv) | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| GB9423970D0 (en) | 1994-11-28 | 1995-01-11 | Astra Ab | Oxidation |
| GB9423968D0 (en) | 1994-11-28 | 1995-01-11 | Astra Ab | Resolution |
| HRP960232A2 (en) | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
| SE510666C2 (sv) | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
| SE510650C2 (sv) | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
| SE510643C2 (sv) * | 1997-06-27 | 1999-06-14 | Astra Ab | Termodynamiskt stabil omeprazol natrium form B |
-
1999
- 1999-01-28 SE SE9900274A patent/SE9900274D0/xx unknown
-
2000
- 2000-01-09 DZ DZ000003A patent/DZ3001A1/xx active
- 2000-01-13 TW TW089100451A patent/TWI269795B/zh not_active IP Right Cessation
- 2000-01-18 SK SK1037-2001A patent/SK285626B6/sk not_active IP Right Cessation
- 2000-01-18 DK DK00903058T patent/DK1149090T3/da active
- 2000-01-18 CZ CZ20012730A patent/CZ300504B6/cs not_active IP Right Cessation
- 2000-01-18 IL IL14410700A patent/IL144107A0/xx not_active IP Right Cessation
- 2000-01-18 JP JP2000596000A patent/JP2002535401A/ja active Pending
- 2000-01-18 DE DE60002042T patent/DE60002042T2/de not_active Expired - Lifetime
- 2000-01-18 CN CNB008032319A patent/CN1231477C/zh not_active Expired - Fee Related
- 2000-01-18 UA UA2001074906A patent/UA71594C2/uk unknown
- 2000-01-18 EP EP00903058A patent/EP1149090B1/en not_active Expired - Lifetime
- 2000-01-18 RS YU53801A patent/RS50200B/sr unknown
- 2000-01-18 SI SI200030105T patent/SI1149090T1/xx unknown
- 2000-01-18 RU RU2001119054A patent/RU2237666C2/ru not_active IP Right Cessation
- 2000-01-18 WO PCT/SE2000/000087 patent/WO2000044744A1/en active IP Right Grant
- 2000-01-18 US US09/530,248 patent/US6511996B1/en not_active Expired - Fee Related
- 2000-01-18 BR BR0007647-3A patent/BR0007647A/pt not_active Application Discontinuation
- 2000-01-18 HU HU0105313A patent/HU226766B1/hu not_active IP Right Cessation
- 2000-01-18 TR TR2001/02138T patent/TR200102138T2/xx unknown
- 2000-01-18 AU AU24694/00A patent/AU768676B2/en not_active Ceased
- 2000-01-18 ES ES00903058T patent/ES2193937T3/es not_active Expired - Lifetime
- 2000-01-18 PT PT00903058T patent/PT1149090E/pt unknown
- 2000-01-18 KR KR1020017009374A patent/KR100624054B1/ko not_active IP Right Cessation
- 2000-01-18 PL PL349721A patent/PL197881B1/pl not_active IP Right Cessation
- 2000-01-18 NZ NZ512804A patent/NZ512804A/en not_active IP Right Cessation
- 2000-01-18 CA CA002357744A patent/CA2357744C/en not_active Expired - Fee Related
- 2000-01-18 AT AT00903058T patent/ATE236899T1/de active
- 2000-01-18 EE EEP200100395A patent/EE04240B1/xx not_active IP Right Cessation
- 2000-01-18 ID IDW00200101639A patent/ID30095A/id unknown
- 2000-01-25 EG EG20000088A patent/EG23980A/xx active
- 2000-01-26 MY MYPI20000260A patent/MY119095A/en unknown
- 2000-01-26 AR ARP000100330A patent/AR022425A1/es active IP Right Grant
- 2000-01-26 SA SA00200895A patent/SA00200895B1/ar unknown
- 2000-01-27 TN TNTNSN00017A patent/TNSN00017A1/fr unknown
-
2001
- 2001-07-04 ZA ZA200105526A patent/ZA200105526B/en unknown
- 2001-07-05 IS IS5989A patent/IS2019B/is unknown
- 2001-07-26 NO NO20013665A patent/NO319719B1/no not_active IP Right Cessation
- 2001-08-24 BG BG105841A patent/BG65060B1/bg unknown
-
2002
- 2002-03-11 HK HK02101846.2A patent/HK1041259B/zh not_active IP Right Cessation
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