PT1274407E - Utilizacao de agonistas de ppar-gama em doencas induzidas por netrofilos - Google Patents

Utilizacao de agonistas de ppar-gama em doencas induzidas por netrofilos

Info

Publication number
PT1274407E
PT1274407E PT00927425T PT00927425T PT1274407E PT 1274407 E PT1274407 E PT 1274407E PT 00927425 T PT00927425 T PT 00927425T PT 00927425 T PT00927425 T PT 00927425T PT 1274407 E PT1274407 E PT 1274407E
Authority
PT
Portugal
Prior art keywords
gama
ppar
netherlands
agonists
utilization
Prior art date
Application number
PT00927425T
Other languages
English (en)
Inventor
Macphee Colin Houston
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PT1274407E publication Critical patent/PT1274407E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B20/00Signal processing not specific to the method of recording or reproducing; Circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
PT00927425T 1999-04-15 2000-04-17 Utilizacao de agonistas de ppar-gama em doencas induzidas por netrofilos PT1274407E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9908647.2A GB9908647D0 (en) 1999-04-15 1999-04-15 Novel compounds

Publications (1)

Publication Number Publication Date
PT1274407E true PT1274407E (pt) 2006-06-30

Family

ID=10851605

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00927425T PT1274407E (pt) 1999-04-15 2000-04-17 Utilizacao de agonistas de ppar-gama em doencas induzidas por netrofilos

Country Status (32)

Country Link
EP (2) EP1593379A3 (pt)
JP (1) JP2003516310A (pt)
KR (1) KR20010108506A (pt)
CN (1) CN1413105A (pt)
AP (1) AP2001002291A0 (pt)
AT (1) ATE319437T1 (pt)
AU (1) AU4583000A (pt)
BG (1) BG106104A (pt)
BR (1) BR0009776A (pt)
CA (1) CA2370127A1 (pt)
CZ (1) CZ20013688A3 (pt)
DE (1) DE60026508T2 (pt)
DK (1) DK1274407T3 (pt)
DZ (1) DZ3151A1 (pt)
EA (1) EA200101089A1 (pt)
ES (1) ES2256003T3 (pt)
GB (1) GB9908647D0 (pt)
HK (1) HK1053788A1 (pt)
HR (1) HRP20010746A2 (pt)
HU (1) HUP0300479A2 (pt)
ID (1) ID30339A (pt)
IL (1) IL145875A0 (pt)
MA (1) MA25351A1 (pt)
MX (1) MXPA01010428A (pt)
NO (1) NO20014950L (pt)
PL (1) PL364720A1 (pt)
PT (1) PT1274407E (pt)
SK (1) SK14532001A3 (pt)
TR (1) TR200102977T2 (pt)
WO (1) WO2000062766A2 (pt)
YU (1) YU77901A (pt)
ZA (1) ZA200108446B (pt)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9913782D0 (en) * 1999-06-14 1999-08-11 Smithkline Beecham Plc Novel compounds
DE50012500D1 (de) * 2000-11-09 2006-05-18 Phenion Gmbh & Co Kg Ppar-alpha,beta-aktivatoren zur behandlung von alopecia areata und vitiligo
GB0030845D0 (en) * 2000-12-18 2001-01-31 Smithkline Beecham Plc Novel treatment
GB2373725A (en) * 2001-03-30 2002-10-02 Novartis Ag Use of a PPAR gamma agonist in the production of a medicament for the prevention or treatment of diseases associated with IL-10 production
AU2002343094A1 (en) * 2001-11-26 2003-06-10 Arachnova Therapeutics Ltd. Use of ppar activators for the treatment of pulmonary fibrosis
DE10204398A1 (de) * 2002-02-04 2003-08-14 Univ Goettingen Georg August Neue Verwendung von Liganden der 'Peroxisome Proliferator-Activated receptors'(PPAR)
US8293479B2 (en) 2002-05-02 2012-10-23 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Use of parathyroid hormone-related protein(PTHRP) in the diagnosis and treatment of chronic lung disease and other pathologies
US6992093B2 (en) 2002-05-02 2006-01-31 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Method of inhibiting lipofibroblast to myofibroblast transdifferentiation
US20030220300A1 (en) * 2002-05-14 2003-11-27 Hwang Cheng Shine Reduction of hair growth
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
KR101333089B1 (ko) 2006-05-22 2013-11-27 재단법인 아산사회복지재단 로지글리타존을 유효성분으로 함유하는 흡연-유발 만성폐쇄성 폐질환 예방 또는 치료용 약제학적 조성물
GB0913672D0 (en) 2009-08-05 2009-09-16 Argenta Discovery Ltd Glitazones
ES2399179T3 (es) * 2008-08-07 2013-03-26 Pulmagen Therapeutics (Inflammation) Limited Tratamiento de enfermedad respiratoria
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
NZ594157A (en) 2008-12-30 2013-07-26 Pulmagen Therapeutics Inflammation Ltd Sulfonamide compounds for the treatment of respiratory disorders
JP5715070B2 (ja) 2009-02-16 2015-05-07 ノグラ ファーマ リミテッド アルキルアミド化合物およびその使用
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
CN104254327A (zh) 2012-02-09 2014-12-31 诺格拉制药有限公司 治疗纤维化的方法
WO2013156413A1 (en) 2012-04-18 2013-10-24 Nogra Pharma Limited Methods of treating lactose intolerance
AU2015315324A1 (en) * 2014-09-08 2017-03-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer comprising administering a PPAR-gamma agonist
JP7100854B2 (ja) * 2017-01-13 2022-07-14 東菱薬品工業株式会社 好中球活性化調節剤
CN113825739A (zh) 2019-02-08 2021-12-21 诺格拉制药有限公司 制备3-(4’-氨基苯基)-2-甲氧基丙酸及其类似物和中间体的方法
JP2020145939A (ja) * 2019-03-12 2020-09-17 日本製粉株式会社 アレルギー性鼻炎抑制用組成物
CN116531374A (zh) * 2023-04-20 2023-08-04 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 吡格列酮及其盐在制备用于治疗系统性红斑狼疮的产品中的应用

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Publication number Priority date Publication date Assignee Title
GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
JPH10139665A (ja) * 1996-09-12 1998-05-26 Sankyo Co Ltd トログリタゾンを含有するグルタチオン還元酵素活性増強剤
ATE253903T1 (de) * 1996-12-11 2003-11-15 Dana Farber Cancer Inst Inc Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor
CA2276288A1 (en) * 1996-12-31 1998-07-09 Laszlo Nagy Treatment of disease states which result from neoplastic cell proliferation using ppar-gamma activators and compositions useful therefor
FR2773075B1 (fr) * 1997-12-31 2000-05-05 Cird Galderma Utilisation d'activateurs de ppar-gamma en dermatologie
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives

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Publication number Publication date
ZA200108446B (en) 2003-08-27
HRP20010746A2 (en) 2002-10-31
IL145875A0 (en) 2002-07-25
AP2001002291A0 (en) 2001-12-31
NO20014950D0 (no) 2001-10-11
ID30339A (id) 2001-11-22
TR200102977T2 (tr) 2002-09-23
SK14532001A3 (sk) 2002-02-05
HUP0300479A2 (hu) 2003-07-28
ES2256003T3 (es) 2006-07-16
EA200101089A1 (ru) 2002-10-31
EP1274407A2 (en) 2003-01-15
EP1274407B1 (en) 2006-03-08
CA2370127A1 (en) 2000-10-26
MA25351A1 (fr) 2001-12-31
CZ20013688A3 (cs) 2003-03-12
AU4583000A (en) 2000-11-02
KR20010108506A (ko) 2001-12-07
CN1413105A (zh) 2003-04-23
YU77901A (sh) 2005-07-19
WO2000062766A3 (en) 2002-10-31
HK1053788A1 (zh) 2003-11-07
BR0009776A (pt) 2002-06-04
DK1274407T3 (da) 2006-06-26
DE60026508T2 (de) 2006-11-16
WO2000062766A2 (en) 2000-10-26
NO20014950L (no) 2001-12-13
MXPA01010428A (es) 2002-05-06
EP1593379A3 (en) 2007-10-31
GB9908647D0 (en) 1999-06-09
PL364720A1 (en) 2004-12-13
JP2003516310A (ja) 2003-05-13
EP1593379A2 (en) 2005-11-09
BG106104A (en) 2002-05-31
ATE319437T1 (de) 2006-03-15
DE60026508D1 (de) 2006-05-04
DZ3151A1 (fr) 2000-10-19

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