ATE240341T1 - C-pyrazol a2a rezeptor agonisten - Google Patents

C-pyrazol a2a rezeptor agonisten

Info

Publication number
ATE240341T1
ATE240341T1 AT00943022T AT00943022T ATE240341T1 AT E240341 T1 ATE240341 T1 AT E240341T1 AT 00943022 T AT00943022 T AT 00943022T AT 00943022 T AT00943022 T AT 00943022T AT E240341 T1 ATE240341 T1 AT E240341T1
Authority
AT
Austria
Prior art keywords
pyrazole
receptor agonists
agonists
receptor
Prior art date
Application number
AT00943022T
Other languages
English (en)
Inventor
Jeff A Zablocki
Elfatih O Elzein
Venkata P Palle
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Application granted granted Critical
Publication of ATE240341T1 publication Critical patent/ATE240341T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00943022T 1999-06-22 2000-06-21 C-pyrazol a2a rezeptor agonisten ATE240341T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/338,327 US6214807B1 (en) 1999-06-22 1999-06-22 C-pyrazole 2A A receptor agonists
PCT/US2000/017095 WO2000078778A2 (en) 1999-06-22 2000-06-21 C-pyrazole a2a receptor agonists

Publications (1)

Publication Number Publication Date
ATE240341T1 true ATE240341T1 (de) 2003-05-15

Family

ID=23324355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00943022T ATE240341T1 (de) 1999-06-22 2000-06-21 C-pyrazol a2a rezeptor agonisten

Country Status (23)

Country Link
US (6) US6214807B1 (de)
EP (1) EP1192169B1 (de)
JP (1) JP4795591B2 (de)
KR (1) KR100511733B1 (de)
CN (1) CN1152041C (de)
AR (1) AR033794A1 (de)
AT (1) ATE240341T1 (de)
AU (1) AU766712B2 (de)
BR (1) BR0011854A (de)
CA (1) CA2375430C (de)
DE (1) DE60002722T2 (de)
DK (1) DK1192169T3 (de)
ES (1) ES2193969T3 (de)
HK (1) HK1044953A1 (de)
IL (2) IL147195A0 (de)
MX (1) MXPA01013350A (de)
NO (1) NO323163B1 (de)
NZ (1) NZ516335A (de)
PT (1) PT1192169E (de)
TR (1) TR200200320T2 (de)
TW (1) TW589321B (de)
WO (1) WO2000078778A2 (de)
ZA (1) ZA200200298B (de)

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Also Published As

Publication number Publication date
IL147195A (en) 2007-10-31
CA2375430A1 (en) 2000-12-28
AU5755800A (en) 2001-01-09
WO2000078778A2 (en) 2000-12-28
TW589321B (en) 2004-06-01
US6770634B1 (en) 2004-08-03
NO20016351D0 (no) 2001-12-21
US7553823B2 (en) 2009-06-30
DE60002722T2 (de) 2004-04-08
US20040198692A1 (en) 2004-10-07
US20070207978A1 (en) 2007-09-06
TR200200320T2 (tr) 2002-05-21
JP2003506460A (ja) 2003-02-18
MXPA01013350A (es) 2002-07-09
IL147195A0 (en) 2002-08-14
US20100081810A1 (en) 2010-04-01
US6214807B1 (en) 2001-04-10
AU766712B2 (en) 2003-10-23
ES2193969T3 (es) 2003-11-16
US6855818B2 (en) 2005-02-15
US20010018428A1 (en) 2001-08-30
CN1358189A (zh) 2002-07-10
KR100511733B1 (ko) 2005-08-31
EP1192169A2 (de) 2002-04-03
KR20020028911A (ko) 2002-04-17
HK1044953A1 (zh) 2002-11-08
NZ516335A (en) 2003-10-31
CA2375430C (en) 2006-03-14
BR0011854A (pt) 2002-06-11
JP4795591B2 (ja) 2011-10-19
DE60002722D1 (de) 2003-06-18
EP1192169B1 (de) 2003-05-14
NO323163B1 (no) 2007-01-08
US7109180B2 (en) 2006-09-19
NO20016351L (no) 2002-02-18
PT1192169E (pt) 2003-09-30
WO2000078778A3 (en) 2001-05-10
ZA200200298B (en) 2003-04-30
DK1192169T3 (da) 2003-08-04
AR033794A1 (es) 2004-01-07
CN1152041C (zh) 2004-06-02

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