PL1989214T3 - Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów - Google Patents

Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów

Info

Publication number
PL1989214T3
PL1989214T3 PL07763545T PL07763545T PL1989214T3 PL 1989214 T3 PL1989214 T3 PL 1989214T3 PL 07763545 T PL07763545 T PL 07763545T PL 07763545 T PL07763545 T PL 07763545T PL 1989214 T3 PL1989214 T3 PL 1989214T3
Authority
PL
Poland
Prior art keywords
polymorphs
preparing
receptor agonist
adenosine receptor
adenosine
Prior art date
Application number
PL07763545T
Other languages
English (en)
Inventor
Jeff Zablocki
Elfatih Elzein
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38120353&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1989214(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of PL1989214T3 publication Critical patent/PL1989214T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL07763545T 2006-02-03 2007-02-02 Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów PL1989214T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76511406P 2006-02-03 2006-02-03
US80185706P 2006-05-18 2006-05-18
EP07763545.6A EP1989214B8 (en) 2006-02-03 2007-02-02 Process for preparing an a2a-adenosine receptor agonist and its polymorphs

Publications (1)

Publication Number Publication Date
PL1989214T3 true PL1989214T3 (pl) 2017-07-31

Family

ID=38120353

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07763545T PL1989214T3 (pl) 2006-02-03 2007-02-02 Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów

Country Status (18)

Country Link
US (8) US7732595B2 (pl)
EP (2) EP1989214B8 (pl)
JP (3) JP5326156B2 (pl)
KR (2) KR20080090491A (pl)
CN (1) CN102260311A (pl)
AU (1) AU2007212542B2 (pl)
CA (1) CA2640089C (pl)
ES (1) ES2593028T3 (pl)
HK (1) HK1127358A1 (pl)
IL (2) IL193153A (pl)
MX (1) MX2010014060A (pl)
NO (1) NO341322B1 (pl)
NZ (1) NZ570239A (pl)
PL (1) PL1989214T3 (pl)
PT (1) PT1989214T (pl)
RU (1) RU2447081C2 (pl)
SI (1) SI1989214T1 (pl)
WO (1) WO2007092372A1 (pl)

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MXPA05001123A (es) * 2002-07-29 2005-04-29 Cv Therapeutics Inc Formacion de imagenes por perfusion de miocardio mediante el uso de agonistas receptores de a2a.
US20050020915A1 (en) * 2002-07-29 2005-01-27 Cv Therapeutics, Inc. Myocardial perfusion imaging methods and compositions
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PL1989214T3 (pl) * 2006-02-03 2017-07-31 Gilead Sciences, Inc. Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów
JP2009541354A (ja) * 2006-06-22 2009-11-26 シーブイ・セラピューティクス・インコーポレイテッド 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用
EP2056834B1 (en) * 2006-09-01 2012-08-29 Gilead Sciences, Inc. Methods and compositions for increasing patient tolerability during myocardial imaging methods
US20090081120A1 (en) * 2006-09-01 2009-03-26 Cv Therapeutics, Inc. Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods
JP2011502101A (ja) * 2006-09-29 2011-01-20 ギリアード・パロ・アルト・インコーポレイテッド 肺疾患の病歴を有する患者における心筋画像化法
CA2673653A1 (en) * 2007-01-03 2008-07-17 Cv Therapeutics, Inc. Myocardial perfusion imaging
CA2685589C (en) * 2007-05-17 2014-09-16 Cv Therapeutics, Inc. Process for preparing an a2a-adenosine receptor agonist and its polymorphs
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CZ308577B6 (cs) * 2011-08-18 2020-12-16 Farmak, A. S. Způsob přípravy 2-(4-methoxykarbonylpyrazol-1-yl)adenosinu a 2-(4-ethoxykarbonylpyrazol-1-yl)adenosinu
CZ304053B6 (cs) * 2011-08-22 2013-09-04 Farmak, A. S. Zpusob prípravy 2-[4-[(methylamino)karbonyl]-1-H-pyrazol-1-yl]adenosinu monohydrátu
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EP2789624B1 (en) * 2013-04-11 2020-09-23 AMRI Italy S.r.l. Stable solid forms of regadenoson
CZ305213B6 (cs) 2013-04-29 2015-06-10 Farmak, A. S. Polymorf E 2-[4-[(methylamino)karbonyl]-1H-pyrazol-1-yl]adenosinu a způsob jeho přípravy
EP3003320A4 (en) * 2013-05-30 2016-10-19 Biophore India Pharmaceuticals Pvt Ltd NEW POLYMORPHE OF REGADENOSON
US9771390B2 (en) 2013-12-10 2017-09-26 Scinopharm Taiwan, Ltd. Process for the preparation of regadenoson
CN105085593A (zh) * 2014-04-21 2015-11-25 上海紫源制药有限公司 瑞加德松的晶型及其制备方法
CN105198950B (zh) * 2014-06-17 2018-10-02 上海紫源制药有限公司 一种瑞加德松晶型e的制备方法
CN105175468B (zh) * 2014-06-17 2018-06-19 上海紫源制药有限公司 一种瑞加德松晶型b的制备方法
US10442832B2 (en) 2015-02-06 2019-10-15 Apicore Us Llc Process of making regadenoson and novel polymorph thereof
US9809617B2 (en) 2015-07-03 2017-11-07 Shanghai Ziyuan Pharmaceutical Co., Ltd. Crystal form of regadenoson and preparation method thereof
CN106397442B (zh) * 2015-07-28 2020-03-27 国药集团国瑞药业有限公司 一种瑞加德松的纯化方法
US10392417B2 (en) 2016-11-04 2019-08-27 Apicore Us Llc Polymorph of regadenoson and process for preparation thereof
CN106749254B (zh) * 2017-01-10 2018-05-25 青岛科技大学 一种6-氨基嘌呤乙基萘乙酸酯类化合物及其作为植物生长调节剂的用途
WO2019191389A1 (en) 2018-03-29 2019-10-03 Johnson Matthey Public Limited Company Solid-state forms of regadenoson, their use and preparation
US10815265B2 (en) 2018-06-29 2020-10-27 Usv Private Limited Process for preparation of regadenoson and polymorphs thereof

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Also Published As

Publication number Publication date
US9085601B2 (en) 2015-07-21
IL252700A0 (en) 2017-08-31
CA2640089A1 (en) 2007-08-16
US20140213539A1 (en) 2014-07-31
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US20110257387A1 (en) 2011-10-20
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