HK1053788A1 - Ppar-gamma拮抗劑在中性粒細胞-誘導的疾病中的用途 - Google Patents

Ppar-gamma拮抗劑在中性粒細胞-誘導的疾病中的用途

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Publication number
HK1053788A1
HK1053788A1 HK03104497.7A HK03104497A HK1053788A1 HK 1053788 A1 HK1053788 A1 HK 1053788A1 HK 03104497 A HK03104497 A HK 03104497A HK 1053788 A1 HK1053788 A1 HK 1053788A1
Authority
HK
Hong Kong
Prior art keywords
ppar
neutrophil
gamma agonists
induced diseases
diseases
Prior art date
Application number
HK03104497.7A
Other languages
English (en)
Inventor
Houston Macphee Colin
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK1053788A1 publication Critical patent/HK1053788A1/zh

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    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B20/00Signal processing not specific to the method of recording or reproducing; Circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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HK03104497.7A 1999-04-15 2003-06-23 Ppar-gamma拮抗劑在中性粒細胞-誘導的疾病中的用途 HK1053788A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9908647.2A GB9908647D0 (en) 1999-04-15 1999-04-15 Novel compounds
PCT/GB2000/001499 WO2000062766A2 (en) 1999-04-15 2000-04-17 Uses of ppar-gamma agonists in neutrophil-induced diseases

Publications (1)

Publication Number Publication Date
HK1053788A1 true HK1053788A1 (zh) 2003-11-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104497.7A HK1053788A1 (zh) 1999-04-15 2003-06-23 Ppar-gamma拮抗劑在中性粒細胞-誘導的疾病中的用途

Country Status (32)

Country Link
EP (2) EP1274407B1 (zh)
JP (1) JP2003516310A (zh)
KR (1) KR20010108506A (zh)
CN (1) CN1413105A (zh)
AP (1) AP2001002291A0 (zh)
AT (1) ATE319437T1 (zh)
AU (1) AU4583000A (zh)
BG (1) BG106104A (zh)
BR (1) BR0009776A (zh)
CA (1) CA2370127A1 (zh)
CZ (1) CZ20013688A3 (zh)
DE (1) DE60026508T2 (zh)
DK (1) DK1274407T3 (zh)
DZ (1) DZ3151A1 (zh)
EA (1) EA200101089A1 (zh)
ES (1) ES2256003T3 (zh)
GB (1) GB9908647D0 (zh)
HK (1) HK1053788A1 (zh)
HR (1) HRP20010746A2 (zh)
HU (1) HUP0300479A2 (zh)
ID (1) ID30339A (zh)
IL (1) IL145875A0 (zh)
MA (1) MA25351A1 (zh)
MX (1) MXPA01010428A (zh)
NO (1) NO20014950L (zh)
PL (1) PL364720A1 (zh)
PT (1) PT1274407E (zh)
SK (1) SK14532001A3 (zh)
TR (1) TR200102977T2 (zh)
WO (1) WO2000062766A2 (zh)
YU (1) YU77901A (zh)
ZA (1) ZA200108446B (zh)

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GB9913782D0 (en) * 1999-06-14 1999-08-11 Smithkline Beecham Plc Novel compounds
DE50012500D1 (de) * 2000-11-09 2006-05-18 Phenion Gmbh & Co Kg Ppar-alpha,beta-aktivatoren zur behandlung von alopecia areata und vitiligo
GB0030845D0 (en) * 2000-12-18 2001-01-31 Smithkline Beecham Plc Novel treatment
GB2373725A (en) * 2001-03-30 2002-10-02 Novartis Ag Use of a PPAR gamma agonist in the production of a medicament for the prevention or treatment of diseases associated with IL-10 production
EP1465622A1 (en) * 2001-11-26 2004-10-13 Arachnova Therapeutics Ltd. Use of ppar activators for the treatment of pulmonary fibrosis
DE10204398A1 (de) * 2002-02-04 2003-08-14 Univ Goettingen Georg August Neue Verwendung von Liganden der 'Peroxisome Proliferator-Activated receptors'(PPAR)
US6992093B2 (en) 2002-05-02 2006-01-31 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Method of inhibiting lipofibroblast to myofibroblast transdifferentiation
US8293479B2 (en) 2002-05-02 2012-10-23 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Use of parathyroid hormone-related protein(PTHRP) in the diagnosis and treatment of chronic lung disease and other pathologies
US20030220300A1 (en) * 2002-05-14 2003-11-27 Hwang Cheng Shine Reduction of hair growth
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
KR101333089B1 (ko) 2006-05-22 2013-11-27 재단법인 아산사회복지재단 로지글리타존을 유효성분으로 함유하는 흡연-유발 만성폐쇄성 폐질환 예방 또는 치료용 약제학적 조성물
GB0913672D0 (en) 2009-08-05 2009-09-16 Argenta Discovery Ltd Glitazones
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
BRPI0917567A2 (pt) * 2008-08-07 2015-11-17 Pulmagen Therapeutics Inflammation Ltd tratamento de doença respiratória
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
ES2442343T3 (es) 2008-12-30 2014-02-11 Pulmagen Therapeutics (Inflammation) Limited Compuestos de sulfonamida para el tratamiento de trastornos respiratorios
EP2396082B1 (en) 2009-02-16 2013-07-31 Nogra Pharma Limited Methods for treating hair related conditions
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
EP2811993B1 (en) 2012-02-09 2019-10-09 Nogra Pharma Limited Methods of treating fibrosis
NZ631049A (en) 2012-04-18 2017-02-24 Nogra Pharma Ltd Methods of treating lactose intolerance
WO2016040313A2 (en) * 2014-09-08 2016-03-17 Dana-Farber Cancer Institute, Inc. Methods of treating cancer
CA3049856C (en) * 2017-01-13 2021-10-26 Tobishi Pharmaceutical Co., Ltd. Neutrophil activation regulator
US11905232B2 (en) 2019-02-08 2024-02-20 Nogra Pharma Limited Process of making 3-(4′-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof
JP2020145939A (ja) * 2019-03-12 2020-09-17 日本製粉株式会社 アレルギー性鼻炎抑制用組成物
CN116531374A (zh) * 2023-04-20 2023-08-04 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 吡格列酮及其盐在制备用于治疗系统性红斑狼疮的产品中的应用

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GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
JPH10139665A (ja) * 1996-09-12 1998-05-26 Sankyo Co Ltd トログリタゾンを含有するグルタチオン還元酵素活性増強剤
EP1410799B1 (en) * 1996-12-11 2010-03-31 Dana-Farber Cancer Institute, Inc. Methods and pharmaceutical compositions for inhibiting tumour cell growth
CA2276288A1 (en) * 1996-12-31 1998-07-09 Laszlo Nagy Treatment of disease states which result from neoplastic cell proliferation using ppar-gamma activators and compositions useful therefor
FR2773075B1 (fr) * 1997-12-31 2000-05-05 Cird Galderma Utilisation d'activateurs de ppar-gamma en dermatologie
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives

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NO20014950D0 (no) 2001-10-11
ZA200108446B (en) 2003-08-27
YU77901A (sh) 2005-07-19
CN1413105A (zh) 2003-04-23
DZ3151A1 (fr) 2000-10-19
BG106104A (en) 2002-05-31
EP1593379A2 (en) 2005-11-09
KR20010108506A (ko) 2001-12-07
TR200102977T2 (tr) 2002-09-23
ID30339A (id) 2001-11-22
NO20014950L (no) 2001-12-13
BR0009776A (pt) 2002-06-04
AU4583000A (en) 2000-11-02
DE60026508T2 (de) 2006-11-16
MXPA01010428A (es) 2002-05-06
ATE319437T1 (de) 2006-03-15
AP2001002291A0 (en) 2001-12-31
HRP20010746A2 (en) 2002-10-31
CA2370127A1 (en) 2000-10-26
PL364720A1 (en) 2004-12-13
GB9908647D0 (en) 1999-06-09
WO2000062766A2 (en) 2000-10-26
HUP0300479A2 (hu) 2003-07-28
EP1274407A2 (en) 2003-01-15
CZ20013688A3 (cs) 2003-03-12
SK14532001A3 (sk) 2002-02-05
ES2256003T3 (es) 2006-07-16
EP1593379A3 (en) 2007-10-31
EA200101089A1 (ru) 2002-10-31
IL145875A0 (en) 2002-07-25
JP2003516310A (ja) 2003-05-13
PT1274407E (pt) 2006-06-30
WO2000062766A3 (en) 2002-10-31
EP1274407B1 (en) 2006-03-08
DK1274407T3 (da) 2006-06-26
DE60026508D1 (de) 2006-05-04
MA25351A1 (fr) 2001-12-31

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