EP1179000A4 - Secreted proteins and uses thereof - Google Patents

Secreted proteins and uses thereof

Info

Publication number
EP1179000A4
EP1179000A4 EP00912028A EP00912028A EP1179000A4 EP 1179000 A4 EP1179000 A4 EP 1179000A4 EP 00912028 A EP00912028 A EP 00912028A EP 00912028 A EP00912028 A EP 00912028A EP 1179000 A4 EP1179000 A4 EP 1179000A4
Authority
EP
European Patent Office
Prior art keywords
secreted proteins
secreted
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP00912028A
Other languages
German (de)
French (fr)
Other versions
EP1179000A2 (en
Inventor
Christopher C Fraser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Priority to EP10008833A priority Critical patent/EP2301947A3/en
Publication of EP1179000A2 publication Critical patent/EP1179000A2/en
Publication of EP1179000A4 publication Critical patent/EP1179000A4/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP00912028A 1999-02-26 2000-02-25 Secreted proteins and uses thereof Ceased EP1179000A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10008833A EP2301947A3 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US259387 1994-06-14
US25938799A 1999-02-26 1999-02-26
PCT/US2000/005035 WO2000050443A2 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Publications (2)

Publication Number Publication Date
EP1179000A2 EP1179000A2 (en) 2002-02-13
EP1179000A4 true EP1179000A4 (en) 2005-10-12

Family

ID=22984735

Family Applications (2)

Application Number Title Priority Date Filing Date
EP10008833A Withdrawn EP2301947A3 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof
EP00912028A Ceased EP1179000A4 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP10008833A Withdrawn EP2301947A3 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Country Status (3)

Country Link
EP (2) EP2301947A3 (en)
AU (1) AU3382800A (en)
WO (1) WO2000050443A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1592786E (en) * 2003-02-11 2012-01-19 Shire Human Genetic Therapies Diagnosis and treatment of multiple sulfatase deficiency and other using a formylglycine generating enzyme (fge)
JP5272310B2 (en) * 2004-10-21 2013-08-28 小野薬品工業株式会社 Uses of immunosuppressive receptors
WO2007122815A1 (en) * 2006-04-14 2007-11-01 Ono Pharmaceutical Co., Ltd. Bivalent antibody directed against bir1
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
KR101380740B1 (en) 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 Purification of iduronate-2-sulfatase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006439A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM
WO1999033982A2 (en) * 1997-12-23 1999-07-08 Chiron Corporation Human genes and gene expression products i

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4870009A (en) 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
JPS6147500A (en) 1984-08-15 1986-03-07 Res Dev Corp Of Japan Chimera monoclonal antibody and its preparation
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61134325A (en) 1984-12-04 1986-06-21 Teijin Ltd Expression of hybrid antibody gene
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
EP0247091B1 (en) 1985-11-01 1993-09-29 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
ATE141646T1 (en) 1986-04-09 1996-09-15 Genzyme Corp GENETICALLY TRANSFORMED ANIMALS THAT SECRETE A DESIRED PROTEIN IN MILK
US4902505A (en) 1986-07-30 1990-02-20 Alkermes Chimeric peptides for neuropeptide delivery through the blood-brain barrier
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US5080891A (en) 1987-08-03 1992-01-14 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL91501A (en) 1988-09-02 1998-03-10 Dyax Corp Generation of a variegated library of mutant potential binding proteins and screening of said library for proteins with a desired binding activity
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5750373A (en) 1990-12-03 1998-05-12 Genentech, Inc. Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants
FR2646438B1 (en) 1989-03-20 2007-11-02 Pasteur Institut A METHOD FOR SPECIFIC REPLACEMENT OF A COPY OF A GENE PRESENT IN THE RECEIVER GENOME BY INTEGRATION OF A GENE DIFFERENT FROM THAT OR INTEGRATION
US5328470A (en) 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
JPH04501510A (en) 1989-07-25 1992-03-19 セル ジェネシス,インコーポレイティド Homologous recombination for universal donor cells and chimeric mammalian hosts
US5264554A (en) * 1990-01-19 1993-11-23 The Blood Center Of Southeastern Wisconsin, Inc. Platelet cell adhesion molecule and variants thereof
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
MA22668A1 (en) 1990-07-10 1993-07-01 Smithkline Beecham Corp PROCESS FOR THE PREPARATION OF OXAMIDES.
EP0585287B1 (en) 1990-07-10 1999-10-13 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DE69133476T2 (en) 1990-08-29 2006-01-05 GenPharm International, Inc., Palo Alto Transgenic mice capable of producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ES2287206T3 (en) 1991-03-01 2007-12-16 Dyax Corporation PROCESS FOR THE DEVELOPMENT OF MINI-PROTEINS OF UNION.
AU662148B2 (en) 1991-04-10 1995-08-24 Scripps Research Institute, The Heterodimeric receptor libraries using phagemids
DE4122599C2 (en) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid for screening antibodies
WO1993004169A1 (en) 1991-08-20 1993-03-04 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
CA2148252C (en) 1992-10-30 2007-06-12 Roger Brent Interaction trap system for isolating novel proteins
CA2153387A1 (en) 1993-01-07 1994-07-21 Hubert Koester Dna sequencing by mass spectrometry
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
GB9517780D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US6473425B1 (en) 1997-10-02 2002-10-29 Sun Microsystems, Inc. Mechanism for dispatching packets via a telecommunications network

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006439A2 (en) * 1997-08-01 1999-02-11 Genset 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM
WO1999033982A2 (en) * 1997-12-23 1999-07-08 Chiron Corporation Human genes and gene expression products i

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BORK P. ET AL: "Powers and pitfalls in sequence analysis: the 70% hurdle", GENOME RESEARCH, vol. 10, 2000, pages 398 - 400, XP002961676 *
BORK P. ET AL: "Predicting function: from genes to genomes and back", J MOL BIOL, vol. 283, no. 4, 6 November 1998 (1998-11-06), pages 707 - 725, XP004457411 *
DATABASE Geneseq [online] 16 June 1999 (1999-06-16), "Human secreted protein 5' EST SEQ ID NO:97.", XP002325730, retrieved from EBI accession no. GSN:AAX40310 Database accession no. AAX40310 *
DATABASE Geneseq [online] 24 September 1999 (1999-09-24), "Human cancer cell derived cDNA contig #37.", retrieved from EBI accession no. GSN:AAX99111 Database accession no. AAX99111 *
DATABASE Geneseq [online] 24 September 1999 (1999-09-24), "Human cancer cell derived cDNA contig #43.", XP002340223, retrieved from EBI accession no. GSN:AAX99117 Database accession no. AAX99117 *
DATABASE UniProt [online] 1 May 1997 (1997-05-01), "Hypothetical protein.", XP002340224, retrieved from EBI accession no. UNIPROT:P95060 Database accession no. P95060 *
MAEDA K ET AL: "Analysis of an expression profile of genes in the human adipose tissue", GENE, ELSEVIER, AMSTERDAM, NL, vol. 190, 1997, pages 227 - 235, XP002136672, ISSN: 0378-1119 *
PIROZZI G ET AL: "IDENTIFICATION AND CHARACTERIZATION OF A NOVEL SURFACE ANTIGEN GENEINDUCED IN MAST CELLS ACTIVATED THROUGH THE HIGH AFFINITY IGE RECEPTOR", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 155, 1995, pages 5811 - 5818, XP001019111, ISSN: 0022-1767 *
See also references of WO0050443A2 *

Also Published As

Publication number Publication date
WO2000050443A9 (en) 2001-12-06
WO2000050443A3 (en) 2000-12-21
EP1179000A2 (en) 2002-02-13
EP2301947A3 (en) 2011-11-23
AU3382800A (en) 2000-09-14
WO2000050443A2 (en) 2000-08-31
EP2301947A2 (en) 2011-03-30

Similar Documents

Publication Publication Date Title
EP1218411A4 (en) Secreted proteins and uses thereof
EP1175438A4 (en) 62 human secreted proteins
EP1165827A4 (en) 45 human secreted proteins
EP1140976A4 (en) Secreted proteins and uses thereof
EP1159284A4 (en) 33 human secreted proteins
AU6394400A (en) Secreted proteins and uses thereof
AU2002211220A1 (en) Secreted proteins and their uses
EP1189938A4 (en) Secreted proteins and uses thereof
AU5907800A (en) Membrane-associated and secreted proteins and uses thereof
EP1173477A4 (en) 49 human secreted proteins
EP1179000A4 (en) Secreted proteins and uses thereof
AU2001290551A1 (en) Secreted proteins and their uses
EP1144614A4 (en) 33 human secreted proteins
EP1171460A4 (en) 48 human secreted proteins
EP1165602A4 (en) 49 human secreted proteins
EP1169332A4 (en) 49 human secreted proteins
EP1165828A4 (en) 50 human secreted proteins
WO2000069885A8 (en) Secreted proteins and uses thereof
AU1190801A (en) Secreted proteins and uses thereof
EP1159413A4 (en) Secreted proteins and uses thereof
EP1165591A4 (en) 47 human secreted proteins
EP1165123A4 (en) 48 human secreted proteins
EP1159287A4 (en) 50 human secreted proteins
EP1171626A4 (en) 50 human secreted proteins
AU5907200A (en) Secreted proteins and uses thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010926

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20050829

17Q First examination report despatched

Effective date: 20051025

APBK Appeal reference recorded

Free format text: ORIGINAL CODE: EPIDOSNREFNE

APBN Date of receipt of notice of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA2E

APBR Date of receipt of statement of grounds of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA3E

APAF Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNE

REG Reference to a national code

Ref country code: DE

Ref legal event code: R003

APBT Appeal procedure closed

Free format text: ORIGINAL CODE: EPIDOSNNOA9E

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20110512