DK1274407T3 - Anvendelse af PPAR-gamma-agonister til neutrofil-inducerede sygdomme - Google Patents

Anvendelse af PPAR-gamma-agonister til neutrofil-inducerede sygdomme

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Publication number
DK1274407T3
DK1274407T3 DK00927425T DK00927425T DK1274407T3 DK 1274407 T3 DK1274407 T3 DK 1274407T3 DK 00927425 T DK00927425 T DK 00927425T DK 00927425 T DK00927425 T DK 00927425T DK 1274407 T3 DK1274407 T3 DK 1274407T3
Authority
DK
Denmark
Prior art keywords
neutrophil
ppar gamma
gamma agonists
induced diseases
diseases
Prior art date
Application number
DK00927425T
Other languages
Danish (da)
English (en)
Inventor
Colin Houston Macphee
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of DK1274407T3 publication Critical patent/DK1274407T3/da

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    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B20/00—Signal processing not specific to the method of recording or reproducing; Circuits therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Neurology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
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  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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DK00927425T 1999-04-15 2000-04-17 Anvendelse af PPAR-gamma-agonister til neutrofil-inducerede sygdomme DK1274407T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9908647.2A GB9908647D0 (en) 1999-04-15 1999-04-15 Novel compounds

Publications (1)

Publication Number Publication Date
DK1274407T3 true DK1274407T3 (da) 2006-06-26

Family

ID=10851605

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00927425T DK1274407T3 (da) 1999-04-15 2000-04-17 Anvendelse af PPAR-gamma-agonister til neutrofil-inducerede sygdomme

Country Status (32)

Country Link
EP (2) EP1274407B1 (zh)
JP (1) JP2003516310A (zh)
KR (1) KR20010108506A (zh)
CN (1) CN1413105A (zh)
AP (1) AP2001002291A0 (zh)
AT (1) ATE319437T1 (zh)
AU (1) AU4583000A (zh)
BG (1) BG106104A (zh)
BR (1) BR0009776A (zh)
CA (1) CA2370127A1 (zh)
CZ (1) CZ20013688A3 (zh)
DE (1) DE60026508T2 (zh)
DK (1) DK1274407T3 (zh)
DZ (1) DZ3151A1 (zh)
EA (1) EA200101089A1 (zh)
ES (1) ES2256003T3 (zh)
GB (1) GB9908647D0 (zh)
HK (1) HK1053788A1 (zh)
HR (1) HRP20010746A2 (zh)
HU (1) HUP0300479A2 (zh)
ID (1) ID30339A (zh)
IL (1) IL145875A0 (zh)
MA (1) MA25351A1 (zh)
MX (1) MXPA01010428A (zh)
NO (1) NO20014950L (zh)
PL (1) PL364720A1 (zh)
PT (1) PT1274407E (zh)
SK (1) SK14532001A3 (zh)
TR (1) TR200102977T2 (zh)
WO (1) WO2000062766A2 (zh)
YU (1) YU77901A (zh)
ZA (1) ZA200108446B (zh)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9913782D0 (en) * 1999-06-14 1999-08-11 Smithkline Beecham Plc Novel compounds
WO2002038150A1 (de) * 2000-11-09 2002-05-16 Phenion Gmbh & Co. Kg Aktivatoren von peroxisom-proliferator-aktivierten rezeptoren alpha, beta als arzneimittel zur behandlung von immunologisch bedingten hautstörungen
GB0030845D0 (en) * 2000-12-18 2001-01-31 Smithkline Beecham Plc Novel treatment
GB2373725A (en) * 2001-03-30 2002-10-02 Novartis Ag Use of a PPAR gamma agonist in the production of a medicament for the prevention or treatment of diseases associated with IL-10 production
WO2003045383A1 (en) * 2001-11-26 2003-06-05 Arachnova Therapeutics Ltd. Use of ppar activators for the treatment of pulmonary fibrosis
DE10204398A1 (de) * 2002-02-04 2003-08-14 Univ Goettingen Georg August Neue Verwendung von Liganden der 'Peroxisome Proliferator-Activated receptors'(PPAR)
US8293479B2 (en) 2002-05-02 2012-10-23 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Use of parathyroid hormone-related protein(PTHRP) in the diagnosis and treatment of chronic lung disease and other pathologies
US6992093B2 (en) 2002-05-02 2006-01-31 Los Angeles Biomedical Research Institute At Harbor Ucla Medical Center Method of inhibiting lipofibroblast to myofibroblast transdifferentiation
US20030220300A1 (en) * 2002-05-14 2003-11-27 Hwang Cheng Shine Reduction of hair growth
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
KR101333089B1 (ko) 2006-05-22 2013-11-27 재단법인 아산사회복지재단 로지글리타존을 유효성분으로 함유하는 흡연-유발 만성폐쇄성 폐질환 예방 또는 치료용 약제학적 조성물
CN102170864B (zh) * 2008-08-07 2015-04-01 帕尔马根治疗(炎症)有限公司 呼吸道疾病的治疗
GB0913672D0 (en) 2009-08-05 2009-09-16 Argenta Discovery Ltd Glitazones
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
SG172444A1 (en) 2008-12-30 2011-07-28 Pulmagen Therapeutics Inflammation Ltd Sulfonamide compounds for the treatment of respiratory disorders
EP2396081B1 (en) 2009-02-16 2017-04-05 Nogra Pharma Limited Alkylamido compounds and uses thereof
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
MX364220B (es) 2012-02-09 2019-04-16 Nogra Pharma Ltd Metodos de tratamientos de fibrosis.
IN2014DN08157A (zh) 2012-04-18 2015-05-01 Nogra Pharma Ltd
AU2015315324A1 (en) * 2014-09-08 2017-03-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer comprising administering a PPAR-gamma agonist
RU2742417C1 (ru) * 2017-01-13 2021-02-05 Тобиси Фармасьютикал Ко., Лтд. Регулятор активации нейтрофилов
WO2020161362A1 (en) 2019-02-08 2020-08-13 Nogra Pharma Limited Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof
JP2020145939A (ja) * 2019-03-12 2020-09-17 日本製粉株式会社 アレルギー性鼻炎抑制用組成物
CN116531374A (zh) * 2023-04-20 2023-08-04 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 吡格列酮及其盐在制备用于治疗系统性红斑狼疮的产品中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
JPH10139665A (ja) * 1996-09-12 1998-05-26 Sankyo Co Ltd トログリタゾンを含有するグルタチオン還元酵素活性増強剤
WO1998025598A2 (en) * 1996-12-11 1998-06-18 Dana-Farber Cancer Institute Methods and pharmaceutical compositions for inhibiting tumour cell growth
EP0963199A1 (en) * 1996-12-31 1999-12-15 The Salk Institute For Biological Studies Treatment of disease states which result from neoplastic cell proliferation using ppar-gamma activators and compositions useful therefor
FR2773075B1 (fr) * 1997-12-31 2000-05-05 Cird Galderma Utilisation d'activateurs de ppar-gamma en dermatologie
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives

Also Published As

Publication number Publication date
NO20014950D0 (no) 2001-10-11
WO2000062766A2 (en) 2000-10-26
EP1274407B1 (en) 2006-03-08
PT1274407E (pt) 2006-06-30
DE60026508D1 (de) 2006-05-04
DE60026508T2 (de) 2006-11-16
BR0009776A (pt) 2002-06-04
AU4583000A (en) 2000-11-02
DZ3151A1 (fr) 2000-10-19
ID30339A (id) 2001-11-22
EA200101089A1 (ru) 2002-10-31
KR20010108506A (ko) 2001-12-07
YU77901A (sh) 2005-07-19
EP1593379A3 (en) 2007-10-31
IL145875A0 (en) 2002-07-25
MA25351A1 (fr) 2001-12-31
HUP0300479A2 (hu) 2003-07-28
EP1274407A2 (en) 2003-01-15
WO2000062766A3 (en) 2002-10-31
PL364720A1 (en) 2004-12-13
CA2370127A1 (en) 2000-10-26
ZA200108446B (en) 2003-08-27
ES2256003T3 (es) 2006-07-16
HK1053788A1 (zh) 2003-11-07
AP2001002291A0 (en) 2001-12-31
CZ20013688A3 (cs) 2003-03-12
EP1593379A2 (en) 2005-11-09
MXPA01010428A (es) 2002-05-06
GB9908647D0 (en) 1999-06-09
BG106104A (en) 2002-05-31
NO20014950L (no) 2001-12-13
CN1413105A (zh) 2003-04-23
TR200102977T2 (tr) 2002-09-23
HRP20010746A2 (en) 2002-10-31
ATE319437T1 (de) 2006-03-15
JP2003516310A (ja) 2003-05-13
SK14532001A3 (sk) 2002-02-05

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