PT103843B - Método de isolamento de células precursoras a partir do cordão umbilical humano - Google Patents

Método de isolamento de células precursoras a partir do cordão umbilical humano Download PDF

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Publication number
PT103843B
PT103843B PT103843A PT10384307A PT103843B PT 103843 B PT103843 B PT 103843B PT 103843 A PT103843 A PT 103843A PT 10384307 A PT10384307 A PT 10384307A PT 103843 B PT103843 B PT 103843B
Authority
PT
Portugal
Prior art keywords
cells
umbilical cord
cell
tissue
volume
Prior art date
Application number
PT103843A
Other languages
English (en)
Portuguese (pt)
Other versions
PT103843A (pt
Inventor
Rita Isabel Ganchas Soares
Maria Constanca Baptista Coelho
Jorge Miguel Silva Santos
Jose Paulo Martins
Vera Alexandra Basto
Pedro Estilista Monteiro Da Cruz
Helder Joaquim Soares Da Cruz
Original Assignee
Medinfar Produtos Farmaceutico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medinfar Produtos Farmaceutico filed Critical Medinfar Produtos Farmaceutico
Priority to PT103843A priority Critical patent/PT103843B/pt
Publication of PT103843A publication Critical patent/PT103843A/pt
Publication of PT103843B publication Critical patent/PT103843B/pt
Priority to PCT/IB2008/054067 priority patent/WO2009044379A2/en
Priority to EA201000425A priority patent/EA025532B1/ru
Priority to JP2010527592A priority patent/JP5785394B2/ja
Priority to US12/680,604 priority patent/US9546353B2/en
Priority to ES08807881.1T priority patent/ES2582369T3/es
Priority to CA2701907A priority patent/CA2701907A1/en
Priority to CN200880114557.0A priority patent/CN101868536B/zh
Priority to KR1020107009850A priority patent/KR20100087705A/ko
Priority to AU2008306442A priority patent/AU2008306442B2/en
Priority to EP08807881.1A priority patent/EP2203555B1/en
Priority to MX2010003511A priority patent/MX2010003511A/es
Priority to BRPI0817522-5A2A priority patent/BRPI0817522A2/pt
Priority to IL204788A priority patent/IL204788A/en
Priority to ZA2010/02260A priority patent/ZA201002260B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0604—Whole embryos; Culture medium therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
PT103843A 2007-10-04 2007-10-04 Método de isolamento de células precursoras a partir do cordão umbilical humano PT103843B (pt)

Priority Applications (15)

Application Number Priority Date Filing Date Title
PT103843A PT103843B (pt) 2007-10-04 2007-10-04 Método de isolamento de células precursoras a partir do cordão umbilical humano
MX2010003511A MX2010003511A (es) 2007-10-04 2008-10-03 Método optimizado y definido para el aislamiento y conservación de células precursoras del cordón umbilical humano.
BRPI0817522-5A2A BRPI0817522A2 (pt) 2007-10-04 2008-10-03 Método otimizado e definido de isolamento e preservação de células precursoras a partir do cordão umbilical humano
ES08807881.1T ES2582369T3 (es) 2007-10-04 2008-10-03 Método optimizado y definido para el aislamiento y la preservación de células precursoras de cordón umbilical humano
KR1020107009850A KR20100087705A (ko) 2007-10-04 2008-10-03 인간 탯줄로부터 전구 세포를 분리하고 보존하기 위한 최적화되고 규정된 방법
JP2010527592A JP5785394B2 (ja) 2007-10-04 2008-10-03 ヒト臍帯から前駆細胞を単離及び保存するための最適化され、定義された方法
US12/680,604 US9546353B2 (en) 2007-10-04 2008-10-03 Optimized and defined method for isolation and preservation of precursor cells from human umbilical cord
PCT/IB2008/054067 WO2009044379A2 (en) 2007-10-04 2008-10-03 Optimised and defined method for isolation and preservation of precursor cells from human umbilical cord
CA2701907A CA2701907A1 (en) 2007-10-04 2008-10-03 Optimized and defined method for isolation and preservation of precursor cells from human umbilical cord
CN200880114557.0A CN101868536B (zh) 2007-10-04 2008-10-03 从人脐带分离和保存前体细胞的优化且确定的方法
EA201000425A EA025532B1 (ru) 2007-10-04 2008-10-03 Способ выделения клеток-предшественников из человеческой пуповины
AU2008306442A AU2008306442B2 (en) 2007-10-04 2008-10-03 Optimised and defined method for isolation and preservation of precursor cells from human umbilical cord
EP08807881.1A EP2203555B1 (en) 2007-10-04 2008-10-03 Optimised and defined method for isolation and preservation of precursor cells from human umbilical cord
IL204788A IL204788A (en) 2007-10-04 2010-03-28 A well-defined and effective method for isolating and preserving precursor cells from human @ umbilical cord
ZA2010/02260A ZA201002260B (en) 2007-10-04 2010-03-30 Optimised and defined method for isolation and preservation of precursor cells from human umbilical cord

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT103843A PT103843B (pt) 2007-10-04 2007-10-04 Método de isolamento de células precursoras a partir do cordão umbilical humano

Publications (2)

Publication Number Publication Date
PT103843A PT103843A (pt) 2008-01-09
PT103843B true PT103843B (pt) 2008-08-12

Family

ID=40456372

Family Applications (1)

Application Number Title Priority Date Filing Date
PT103843A PT103843B (pt) 2007-10-04 2007-10-04 Método de isolamento de células precursoras a partir do cordão umbilical humano

Country Status (15)

Country Link
US (1) US9546353B2 (https=)
EP (1) EP2203555B1 (https=)
JP (1) JP5785394B2 (https=)
KR (1) KR20100087705A (https=)
CN (1) CN101868536B (https=)
AU (1) AU2008306442B2 (https=)
BR (1) BRPI0817522A2 (https=)
CA (1) CA2701907A1 (https=)
EA (1) EA025532B1 (https=)
ES (1) ES2582369T3 (https=)
IL (1) IL204788A (https=)
MX (1) MX2010003511A (https=)
PT (1) PT103843B (https=)
WO (1) WO2009044379A2 (https=)
ZA (1) ZA201002260B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2576768B1 (en) 2010-06-01 2017-05-10 Auxocell Laboratories, Inc. Native wharton's jelly stem cells and their purification
TWI523947B (zh) * 2010-10-18 2016-03-01 尚翔股份有限公司 人類多能性類胚胎幹細胞先驅細胞
TWI535377B (zh) * 2011-09-01 2016-06-01 Storage, culture and application of umbilical cord tissue and its derived cells
HUE056817T2 (hu) * 2011-12-30 2022-03-28 Amit Patel Eljárások és készítmények allogén sejt klinikai származtatására és terápiás alkalmazások
CN102550543B (zh) * 2012-02-10 2014-04-16 四川新生命干细胞科技股份有限公司 用于保存脐带组织的液体
CN103461322B (zh) * 2012-06-07 2016-08-03 西比曼生物科技（上海）有限公司 用于冻存复苏后的细胞的保存液
EP2756754B1 (de) 2013-01-17 2017-01-04 Vita 34 Ag Verfahren zur Behandlung von Nabelschnurgewebe, insbesondere im Zusammenhang mit der Konservierung des Gewebes
US20170119824A1 (en) * 2014-05-24 2017-05-04 Neelam Krishnan Venkataramanaa A method for the treatment of glioblastoma with wharton jelly-mesenchymal stem cells (wj-msc) derived from human umbilical cord
JP2017533917A (ja) * 2014-11-05 2017-11-16 ティッシュテック，インク． 神経成長および再生を促進するための組成物および方法
US10006003B2 (en) * 2015-06-30 2018-06-26 Surgenex, LLC Compositions and methods for flowable allograft amniotic tissue
WO2017096611A1 (zh) * 2015-12-11 2017-06-15 郭镭 一种从脐带华通氏胶组织中分离培养脐带间充质干细胞的方法
WO2019175773A1 (en) 2018-03-12 2019-09-19 Universidade Do Porto Compositions for use in the treatment of musculoskeletal conditions and methods for producing the same leveraging the synergistic activity of two different types of mesenchymal stromal/stem cells
CN112342191A (zh) * 2019-08-07 2021-02-09 路春光 hMSC生产试剂盒开发和质量管理标准优化和体系建立
CN111893092A (zh) * 2020-06-28 2020-11-06 国大生命科学产业集团(深圳)有限公司 一种人脐带来源的间充质干细胞及其制备方法
CN113025567A (zh) * 2021-03-31 2021-06-25 中国人民解放军陆军特色医学中心 一种椎间盘单细胞的分离方法
DE102021116694B4 (de) * 2021-06-29 2023-03-09 Promocell Gmbh Wässrige Lösung zur Zellkonservierung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT402890B (de) * 1994-03-16 1997-09-25 Berbi Gmbh Verwendung von notoginsenosid r1 zur herstellung von arzneimitteln
AU2003221173A1 (en) * 2002-03-27 2003-10-08 Asahi Kasei Kabushiki Kaisha Placenta-origin mesenchymal cells and medicinal use thereof
ZA200804717B (en) * 2005-12-29 2010-02-24 Anthrogenesis Corp Improved composition for collecting and preserving a placental stem cells and methods of using the composition
CN101611139B (zh) * 2006-11-13 2012-07-04 伊西康公司 利用微载体的产后来源的细胞的体外扩增

Also Published As

Publication number Publication date
US9546353B2 (en) 2017-01-17
KR20100087705A (ko) 2010-08-05
MX2010003511A (es) 2010-09-10
IL204788A (en) 2013-07-31
EA025532B1 (ru) 2017-01-30
US20100216237A1 (en) 2010-08-26
BRPI0817522A2 (pt) 2014-10-14
JP2010539970A (ja) 2010-12-24
ZA201002260B (en) 2011-06-29
CA2701907A1 (en) 2009-04-09
WO2009044379A2 (en) 2009-04-09
AU2008306442B2 (en) 2014-12-04
EA201000425A1 (ru) 2010-10-29
PT103843A (pt) 2008-01-09
WO2009044379A3 (en) 2009-05-22
EP2203555A2 (en) 2010-07-07
CN101868536B (zh) 2015-03-25
IL204788A0 (en) 2010-12-30
EP2203555B1 (en) 2016-04-13
ES2582369T3 (es) 2016-09-12
AU2008306442A1 (en) 2009-04-09
CN101868536A (zh) 2010-10-20
JP5785394B2 (ja) 2015-09-30

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