PL2089511T3 - Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki - Google Patents

Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki

Info

Publication number
PL2089511T3
PL2089511T3 PL07867434T PL07867434T PL2089511T3 PL 2089511 T3 PL2089511 T3 PL 2089511T3 PL 07867434 T PL07867434 T PL 07867434T PL 07867434 T PL07867434 T PL 07867434T PL 2089511 T3 PL2089511 T3 PL 2089511T3
Authority
PL
Poland
Prior art keywords
microcarriers
postpartum
derived cells
vitro expansion
vitro
Prior art date
Application number
PL07867434T
Other languages
English (en)
Inventor
Alexander M Harmon
Klaudyne L S Hong
Anthony J Kihm
Anna Gosiewska
Original Assignee
Depuy Synthes Products Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Synthes Products Llc filed Critical Depuy Synthes Products Llc
Publication of PL2089511T3 publication Critical patent/PL2089511T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL07867434T 2006-11-13 2007-11-13 Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki PL2089511T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86555806P 2006-11-13 2006-11-13
EP07867434.8A EP2089511B1 (en) 2006-11-13 2007-11-13 In vitro expansion of postpartum-derived cells using microcarriers
PCT/US2007/023846 WO2008060541A2 (en) 2006-11-13 2007-11-13 In vitro expansion of postpartum-derived cells using microcarriers

Publications (1)

Publication Number Publication Date
PL2089511T3 true PL2089511T3 (pl) 2015-02-27

Family

ID=39402235

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07867434T PL2089511T3 (pl) 2006-11-13 2007-11-13 Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki

Country Status (9)

Country Link
US (1) US9102915B2 (pl)
EP (1) EP2089511B1 (pl)
JP (2) JP5670053B2 (pl)
CN (1) CN101611139B (pl)
AU (1) AU2007319820B2 (pl)
CA (1) CA2669589C (pl)
ES (1) ES2524443T3 (pl)
PL (1) PL2089511T3 (pl)
WO (1) WO2008060541A2 (pl)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008535A2 (en) * 2001-07-20 2003-01-30 Technion Research And Development Foundation Ltd. Methods of generating human cardiac cells and tissues and uses thereof
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
JP4950660B2 (ja) * 2003-06-27 2012-06-13 エチコン、インコーポレイテッド 分娩後由来細胞を使用する眼組織の修復および再生
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US8491883B2 (en) 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
AU2005322068B2 (en) 2004-12-23 2011-09-01 Ethicon Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
PL1831356T3 (pl) 2004-12-23 2017-07-31 DePuy Synthes Products, Inc. Komórki poporodowe pochodzące z tkanki pępowinowej i sposoby ich wytwarzania i stosowania
NZ597304A (en) * 2005-10-13 2013-06-28 Anthrogenesis Corp Immunomodulation using placental stem cells
PL1971681T3 (pl) 2005-12-16 2018-01-31 Depuy Synthes Products Inc Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej
CN101410511B (zh) * 2005-12-19 2015-02-25 伊西康公司 产后来源的细胞在滚瓶中的体外扩增
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
EP1976977B1 (en) 2005-12-29 2015-07-08 Anthrogenesis Corporation Placental stem cell populations
CA2673521C (en) 2006-10-12 2017-01-17 Ethicon, Inc. Kidney-derived cells and methods of use in tissue repair and regeneration
JP5670053B2 (ja) 2006-11-13 2015-02-18 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃｏｒｐｏｒａｔｅｄ マイクロキャリアを使用した、産褥由来の細胞の生体外での拡大
CN101657206B (zh) 2007-02-12 2013-07-03 人类起源公司 利用胎盘干细胞治疗炎性疾病
JP5350364B2 (ja) * 2007-04-28 2013-11-27 ヒョンジン ヤン， 粉末状の足場を用いた細胞間の信号調節による細胞培養方法
CN101878034B (zh) 2007-09-28 2013-11-20 细胞基因细胞疗法公司 使用人胎盘灌洗液和人来自胎盘的中间体自然杀伤细胞的肿瘤抑制
PT103843B (pt) * 2007-10-04 2008-08-12 Medinfar Produtos Farmaceutico Método de isolamento de células precursoras a partir do cordão umbilical humano
CN102036688B (zh) 2007-10-05 2014-07-02 伊西康公司 使用人脐带组织来源的细胞进行肾脏组织的修复和再生
US8236538B2 (en) * 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
US8828720B2 (en) * 2008-03-17 2014-09-09 Agency For Science, Technology And Research Microcarriers for stem cell culture
US20120028352A1 (en) * 2008-03-17 2012-02-02 Agency For Science, Technology And Research Microcarriers for Stem Cell Culture
WO2009116951A2 (en) 2008-03-17 2009-09-24 Agency For Science, Technology And Research Microcarriers for stem cell culture
US9458431B2 (en) 2008-03-17 2016-10-04 Agency For Science, Technology And Research Microcarriers for stem cell culture
US20120219531A1 (en) * 2008-03-17 2012-08-30 Agency For Science, Technology And Research Microcarriers for Stem Cell Culture
US8691569B2 (en) * 2008-03-17 2014-04-08 Agency For Science, Technology And Research Microcarriers for stem cell culture
CA2734237C (en) 2008-08-20 2019-07-02 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
KR20200011604A (ko) 2008-08-20 2020-02-03 안트로제네시스 코포레이션 개선된 세포 조성물 및 그의 제조 방법
AU2009283161A1 (en) 2008-08-22 2010-02-25 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
US8367409B2 (en) 2008-11-19 2013-02-05 Anthrogenesis Corporation Amnion derived adherent cells
US20100151575A1 (en) * 2008-12-15 2010-06-17 Colter David C Method of Making Conditioned Media from Kidney Derived Cells
ES2665883T3 (es) 2008-12-19 2018-04-30 DePuy Synthes Products, Inc. Tratamiento de enfermedades y trastornos pulmonares y pulmonares
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
BRPI1013409A2 (pt) 2009-03-26 2018-01-16 Advanced Tech And Regenerative Medicine Llc células de tecido de cordão umbilical humano como terapia para doença de alzheimer
US20100247495A1 (en) * 2009-03-30 2010-09-30 Tom Ichim Treatment of Muscular Dystrophy
WO2011016829A1 (en) * 2009-08-06 2011-02-10 Albert Einstein College Of Medicine Of Yeshiva University Cell therapy for treatment of liver failure
US8278101B2 (en) * 2009-12-07 2012-10-02 Synthecon, Inc. Stem cell bioprocessing and cell expansion
CN102822330A (zh) 2010-01-26 2012-12-12 人类起源公司 使用胎盘干细胞对骨相关癌的治疗
SI2556145T1 (sl) 2010-04-07 2017-01-31 Anthrogenesis Corporation Angiogeneza z uporabo placentnih matičnih celic
WO2011127113A1 (en) 2010-04-08 2011-10-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
EP2575913B1 (en) 2010-05-25 2018-07-25 Cook Biotech Incorporated Methods, substrates, and systems useful for cell seeding of medical grafts
CN102146356A (zh) * 2010-06-24 2011-08-10 辽宁成大生物股份有限公司 一种再生微载体的方法
WO2012009422A1 (en) 2010-07-13 2012-01-19 Anthrogenesis Corporation Methods of generating natural killer cells
EP2606115A4 (en) * 2010-08-16 2017-07-19 Kiyatec Inc. Bioreactor system
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
JP2012165719A (ja) * 2011-02-16 2012-09-06 National Institute Of Advanced Industrial Science & Technology 擬微小重力環境下での三次元癌組織モデルの構築方法
CN113559126A (zh) 2011-06-01 2021-10-29 人类起源公司 利用胎盘干细胞治疗疼痛
US20140170748A1 (en) * 2012-12-14 2014-06-19 DePuy Synthes Products, LLC Nutrient Enriched Media for hUTC Growth
EP3622960A1 (en) 2013-02-05 2020-03-18 Celularity, Inc. Natural killer cells from placenta
ES2709884T3 (es) * 2013-02-19 2019-04-22 Abbott Point Of Care Inc Un método de analizar una muestra de fluido biológico
CA2917073A1 (en) * 2013-06-24 2014-12-31 Anthrogenesis Corporation Extracellular matrix composition beads for cell culture
CN108473936A (zh) * 2015-12-22 2018-08-31 康宁股份有限公司 细胞分离装置及其使用方法
MX2018008712A (es) 2016-01-14 2019-06-06 Depuy Synthes Products Inc Composicion y metodos para la crioconservacion de hutc.
EP3464550B1 (en) 2016-05-31 2020-03-11 Corning Incorporated Vessels and spinner flasks with reduced impeller wobble for culturing cells
WO2018075940A1 (en) * 2016-10-21 2018-04-26 Georgia Tech Research Corporation Methods and systems for t cell expansion
EP3770248A4 (en) * 2018-03-22 2022-01-19 Nikkiso Co., Ltd. CELL CULTURE METHOD, CELL SUPPORT COMPOSITE PRODUCTION METHOD, CULTURED CELLS AND CELL SUPPORT COMPOSITE
WO2020155668A1 (zh) * 2019-01-31 2020-08-06 北京华龛生物科技有限公司 一种用于干细胞大规模制备的三维培养方法
CN111424011A (zh) * 2020-04-17 2020-07-17 深圳市旷逸生物科技有限公司 一种能够维持脐带间充质干细胞细胞形态的三维培养方法
WO2022060015A1 (ko) * 2020-09-15 2022-03-24 주식회사 엘지화학 세포 배양용 마이크로-캐리어 및 그 제조방법

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1220832B (de) * 1964-09-22 1966-07-14 Siemens Ag Ziehduese zum Ziehen von Halbleiterkristallen aus einer Schmelze
US3665061A (en) 1969-07-16 1972-05-23 United States Banknote Corp Process for producing collagen sponges
US4216144A (en) 1977-10-20 1980-08-05 Ashmead H H Soluble iron proteinates
JPS6040439B2 (ja) 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
US4487865A (en) 1983-12-15 1984-12-11 Biomatrix, Inc. Polymeric articles modified with hyaluronate
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4925677A (en) 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5284766A (en) * 1989-02-10 1994-02-08 Kao Corporation Bed material for cell culture
NL9100038A (nl) 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
DE4406073A1 (de) 1994-02-24 1995-08-31 Univ Ludwigs Albert Verfahren zur Herstellung von humanen, klonogenen Fibroblasten, Verfahren zur Gentransfizierung von Fibroblasten und so erhaltene Fibroblasten
US5919702A (en) 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
WO1998052560A1 (en) 1997-05-21 1998-11-26 Sloan-Kettering Institute For Cancer Research Method for increasing the concentration of ascorbic acid in brain tissues of a subject
US7560280B2 (en) * 2000-11-03 2009-07-14 Kourion Therapeutics Gmbh Human cord blood derived unrestricted somatic stem cells (USSC)
EP2316919B1 (en) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
ATE456664T1 (de) 2001-04-02 2010-02-15 Glycomedics Inc Verfahren zur herstellung von oligosaccharidketten
JP4741189B2 (ja) * 2002-02-08 2011-08-03 ユニヴァーシティ オブ サウス フロリダ 増殖した細胞系およびその使用方法
CN1281739C (zh) * 2002-02-19 2006-10-25 美迪宝斯特有限公司 从脐带血中分离并扩大培养间充质干细胞/祖细胞及将脐带血来源的间充质干细胞/祖细胞分化成各种间充质组织的方法
JP2003259862A (ja) * 2002-03-12 2003-09-16 Fuji Photo Film Co Ltd 細胞培養担体
US20060128014A1 (en) 2002-08-26 2006-06-15 Johan Haggblad Compositions and methods for culturing stem cells
GB0222846D0 (en) * 2002-10-03 2002-11-06 Choo Yen Cell culture
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
JP4950660B2 (ja) * 2003-06-27 2012-06-13 エチコン、インコーポレイテッド 分娩後由来細胞を使用する眼組織の修復および再生
US8790637B2 (en) * 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
CN101416059A (zh) * 2003-07-17 2009-04-22 格洛伯塞尔解决方案公司 自动化细胞培养系统及方法
JP4575654B2 (ja) * 2003-09-05 2010-11-04 エスエス製薬株式会社 溶解性と流動性を改善した医薬組成物
DE102004043256B4 (de) * 2004-09-07 2013-09-19 Rheinische Friedrich-Wilhelms-Universität Bonn Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension
JP2008518597A (ja) 2004-10-29 2008-06-05 セントカー・インコーポレーテツド 化学的規定培地組成物
US20060166361A1 (en) 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
AU2005322068B2 (en) 2004-12-23 2011-09-01 Ethicon Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
PL1831356T3 (pl) * 2004-12-23 2017-07-31 DePuy Synthes Products, Inc. Komórki poporodowe pochodzące z tkanki pępowinowej i sposoby ich wytwarzania i stosowania
WO2006088867A2 (en) * 2005-02-15 2006-08-24 Medistem Laboratories, Incorporated Method for expansion of stem cells
DK1864132T3 (da) * 2005-03-31 2012-07-16 Stemnion Inc Fra amnion stammende cellesammensætninger, fremgangsmåder til fremstilling deraf og anvendelser deraf
PL1971681T3 (pl) * 2005-12-16 2018-01-31 Depuy Synthes Products Inc Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej
CN101410511B (zh) 2005-12-19 2015-02-25 伊西康公司 产后来源的细胞在滚瓶中的体外扩增
PT2366775E (pt) 2006-03-23 2015-07-20 Pluristem Ltd Métodos para expansão celular e usos de células e de meios condicionados produzidos através deles para terapia
CA2656175C (en) 2006-06-26 2018-08-28 Lifescan, Inc. Conditioned media obtained from amniotic fluid-derived cells for pluripotent stem cell culture
JP5670053B2 (ja) 2006-11-13 2015-02-18 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃｏｒｐｏｒａｔｅｄ マイクロキャリアを使用した、産褥由来の細胞の生体外での拡大
AU2009327382B2 (en) 2008-12-19 2014-07-17 DePuy Synthes Products, LLC Umbilical cord tissue derived cells for treating neuropathic pain and spasticity
JP6095893B2 (ja) 2008-12-19 2017-03-15 デピュイ・シンセス・プロダクツ・インコーポレイテッド 傷害後の神経組織の再生および修復
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
BRPI1013409A2 (pt) * 2009-03-26 2018-01-16 Advanced Tech And Regenerative Medicine Llc células de tecido de cordão umbilical humano como terapia para doença de alzheimer

Also Published As

Publication number Publication date
CN101611139B (zh) 2012-07-04
AU2007319820A1 (en) 2008-05-22
JP2014236755A (ja) 2014-12-18
JP2010508851A (ja) 2010-03-25
AU2007319820B2 (en) 2013-09-05
US9102915B2 (en) 2015-08-11
US20080166328A1 (en) 2008-07-10
JP5670053B2 (ja) 2015-02-18
EP2089511A2 (en) 2009-08-19
CN101611139A (zh) 2009-12-23
ES2524443T3 (es) 2014-12-09
CA2669589A1 (en) 2008-05-22
WO2008060541A3 (en) 2008-08-28
EP2089511B1 (en) 2014-09-17
CA2669589C (en) 2016-01-12
WO2008060541A2 (en) 2008-05-22

Similar Documents

Publication Publication Date Title
PL2089511T3 (pl) Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
IL276146B1 (en) Laboratory methods for increasing the vitality of the cells of the immune system
IL194438A (en) Diarrhylthiohydantoin Compounds, Pharmaceuticals Containing Them, Syntheses Methods and In Vitro Methods for Contacting them with Mammalian Cells
IL221384A0 (en) Improving il-15 and il-15r-alpha for expression in mammalian cells
GB0605450D0 (en) Cell co-culture
SG10201405107YA (en) Compositions and methods useful for culturing differentiable cells
IL241906A0 (en) Methods for the production and uses of pluripotent cell populations and differentiated cell populations
IL200622A0 (en) Use of copper and glutamate in cell culture for production of polypeptides
GB0622394D0 (en) Differentiation of pluripotent cells
EP2089507A4 (en) HIGHLY EFFICIENT DEVICES AND METHOD FOR CELL CULTIVATION
EP2064324A4 (en) SUBSTRATES FOR CELL CULTURE AND MANUFACTURING METHOD THEREFOR
PL2046946T3 (pl) Hodowla pluripotencjalnych komórek macierzystych
EP1934361A4 (en) METHODS OF REJUVENING IN VITRO AND IN VIVO CELLS
PL3323883T3 (pl) Zdefiniowane powierzchnie do hodowli komórkowej i sposoby użycia
SG10201510384UA (en) Cell culture improvements
HK1138374A1 (en) Methods of evaluating cells and cell cultures
IL194894A0 (en) Substrate for the growth of cultured cells in three dimensions
EP2069477A4 (en) CHEMOREPULSION OF CELLS
EP2227540A4 (en) DIFFERENTIATION OF HUMAN CELLS
GB0606671D0 (en) Cell Culture
EP1923457A4 (en) CULTURE SUPPORT FOR CELLS THAT CAN BE IMPLANTED IN VIVO
IL196803A0 (en) Differential labeling of cells
HK1130076A1 (en) Method of proliferating lak cell lak
EP2205971A4 (en) ENDOTHELIAL CELL MARKERS AND USES THEREOF
GB0718226D0 (en) Method of in vitro diagnosing