DK2078073T3 - Nyreafledte celler og fremgangsmåder til anvendelse deraf til vævsreparation og -regenerering - Google Patents
Nyreafledte celler og fremgangsmåder til anvendelse deraf til vævsreparation og -regenereringInfo
- Publication number
- DK2078073T3 DK2078073T3 DK07852651.4T DK07852651T DK2078073T3 DK 2078073 T3 DK2078073 T3 DK 2078073T3 DK 07852651 T DK07852651 T DK 07852651T DK 2078073 T3 DK2078073 T3 DK 2078073T3
- Authority
- DK
- Denmark
- Prior art keywords
- kidney
- regeneration
- methods
- derived cells
- tissue repair
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0687—Renal stem cells; Renal progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82923806P | 2006-10-12 | 2006-10-12 | |
PCT/US2007/021708 WO2008045498A1 (en) | 2006-10-12 | 2007-10-11 | Kidney-derived cells and methods of use in tissue repair and regeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2078073T3 true DK2078073T3 (da) | 2013-10-28 |
Family
ID=39116540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07852651.4T DK2078073T3 (da) | 2006-10-12 | 2007-10-11 | Nyreafledte celler og fremgangsmåder til anvendelse deraf til vævsreparation og -regenerering |
Country Status (12)
Country | Link |
---|---|
US (2) | US10500230B2 (da) |
EP (1) | EP2078073B1 (da) |
JP (1) | JP5450072B2 (da) |
CN (1) | CN101595212B (da) |
AU (1) | AU2007308168B2 (da) |
CA (1) | CA2673521C (da) |
DK (1) | DK2078073T3 (da) |
ES (1) | ES2432395T3 (da) |
PL (1) | PL2078073T3 (da) |
PT (1) | PT2078073E (da) |
SI (1) | SI2078073T1 (da) |
WO (1) | WO2008045498A1 (da) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7862810B2 (en) * | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
US20110091428A1 (en) * | 2000-07-31 | 2011-04-21 | New York Medical College | Compositions of adult organ stem cells and uses thereof |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
PL1641914T3 (pl) | 2003-06-27 | 2017-01-31 | DePuy Synthes Products, Inc. | Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US20060153815A1 (en) * | 2004-12-21 | 2006-07-13 | Agnieszka Seyda | Tissue engineering devices for the repair and regeneration of tissue |
WO2006083394A2 (en) * | 2004-12-21 | 2006-08-10 | Ethicon, Inc. | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
US20060171930A1 (en) * | 2004-12-21 | 2006-08-03 | Agnieszka Seyda | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
ES2621847T3 (es) | 2004-12-23 | 2017-07-05 | DePuy Synthes Products, Inc. | Células posparto derivadas de tejido de cordón umbilical, y métodos de elaboración y uso de las mismas |
PL1835924T3 (pl) | 2004-12-23 | 2014-01-31 | Ethicon Incorporated | Leczenie choroby Parkinsona i zaburzeń związanych z tą chorobą z użyciem komórek uzyskiwanych po porodzie |
EP1971681B1 (en) | 2005-12-16 | 2017-08-23 | DePuy Synthes Products, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
US8741638B2 (en) * | 2005-12-19 | 2014-06-03 | DePuy Synthes Products, LLC | In vitro expansion of postpartum-derived cells in roller bottles |
AU2006330409B2 (en) * | 2005-12-28 | 2012-07-19 | Ethicon, Incorporated | Treatment of peripheral vascular disease using postpartum-derived cells |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
WO2007092735A2 (en) | 2006-02-02 | 2007-08-16 | Innovative Bio Therapies | An extracorporeal cell-based therapeutic device and delivery system |
PT2078073E (pt) | 2006-10-12 | 2013-11-11 | Ethicon Inc | Células derivadas do rim e métodos de utilização na reparação e regeneração de tecidos |
AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
US10590391B2 (en) | 2007-06-08 | 2020-03-17 | Wake Forest University Health Sciences | Selective cell therapy for the treatment of renal failure |
ES2725502T3 (es) * | 2007-06-08 | 2019-09-24 | Univ Wake Forest Health Sciences | Terapia celular selectiva para el tratamiento de la insuficiencia renal |
US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
EP2187932B1 (en) | 2007-08-07 | 2015-01-28 | DePuy Synthes Products, LLC | Protein formulations comprising gdf-5 in aqueous acidic solution |
BRPI0818183A2 (pt) * | 2007-10-05 | 2019-07-16 | Ethicon Inc | reparo e regeneração do tecido renal usando células derivadas do tecido do cordão umbilical humano |
US8236538B2 (en) * | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
CN102026619A (zh) | 2008-04-14 | 2011-04-20 | 先进科技及再生医学有限责任公司 | 液体缓冲的gdf-5制剂 |
WO2010071692A2 (en) * | 2008-06-18 | 2010-06-24 | Innovative Biotherapies, Inc. | Methods for enhanced propagation of cells |
CN102224241B (zh) * | 2008-10-24 | 2015-02-18 | 洛杉矶儿童医院 | 羊水细胞及其用途 |
EP2186883A1 (en) | 2008-11-04 | 2010-05-19 | Fresenius Medical Care | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
WO2010056328A1 (en) | 2008-11-12 | 2010-05-20 | Tengion, Inc. | Isolated renal cells and uses thereof |
WO2010057015A1 (en) * | 2008-11-14 | 2010-05-20 | Wake Forest University Health Sciences | Kidney structures and methods of forming the same |
US20100151575A1 (en) * | 2008-12-15 | 2010-06-17 | Colter David C | Method of Making Conditioned Media from Kidney Derived Cells |
BRPI0923177A2 (pt) * | 2008-12-19 | 2020-08-25 | Advanced Technologies And Regenerative Medicine, Llc | usos de composições para tratar dor neuropática e espacidade, as referidas composições, e kit |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
CA2747794C (en) | 2008-12-19 | 2018-10-30 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of lung and pulmonary diseases and disorders |
EP2379089B1 (en) * | 2008-12-19 | 2019-04-17 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue following injury |
CA2756600C (en) | 2009-03-26 | 2019-08-20 | Advanced Technologies And Regenerative Medicine, Llc | Human umbilical cord tissue cells as therapy for alzheimer's disease |
US20110142805A1 (en) * | 2009-12-15 | 2011-06-16 | Advanced Technologies And Regenerative Medicine, Llc | Method of renal repair and regeneration and the treatment of diabetic nephropathy |
KR102428776B1 (ko) * | 2010-05-12 | 2022-08-04 | 인리젠 | 생물활성 신장 세포 |
EP2637711B1 (en) | 2010-11-10 | 2024-03-27 | ProKidney | Injectable formulations for organ augmentation |
US8546338B2 (en) | 2010-12-08 | 2013-10-01 | Johnson & Johnson Consumer Companies, Inc. | Self-assembling hydrogels based on dicephalic peptide amphiphiles |
US20120156433A1 (en) | 2010-12-21 | 2012-06-21 | Natarajan Sriram N | Silicone polymer substrates having improved biological response from hkdcs |
US20120156780A1 (en) | 2010-12-21 | 2012-06-21 | Cooper Kevin L | Polymer Substrates Having Improved Biological Response From HKDCS |
PL2714894T3 (pl) | 2011-05-27 | 2020-04-30 | DePuy Synthes Products, Inc. | Systemy biosztucznych kanalików proksymalnych oraz sposoby ich stosowania |
US20130157368A1 (en) * | 2011-12-20 | 2013-06-20 | Advanced Technologies And Regenerative Medicine, Llc | Induced pluripotent stem cells prepared from human kidney-derived cells |
HUE046176T2 (hu) * | 2012-10-24 | 2020-02-28 | Inregen | Vesesejt-populációk és alkalmazásaik |
CN107208055B (zh) * | 2015-01-17 | 2021-06-15 | 浙江大学 | 引起免疫原性反应降低的被修饰细胞 |
DE102016109067B4 (de) | 2016-05-17 | 2018-07-19 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Verfahren zur Bildung von Nierentubuli |
US11123372B2 (en) | 2016-07-29 | 2021-09-21 | Prokidney | Bioactive renal cells for the treatment of chronic kidney disease |
CN106166161A (zh) * | 2016-08-03 | 2016-11-30 | 中国人民解放军总医院 | 用于治疗系膜增生性肾小球肾炎的药物 |
CN106267192A (zh) * | 2016-09-14 | 2017-01-04 | 中国人民解放军总医院 | 一种用于治疗系膜增生性肾炎的药物 |
AU2017377309B9 (en) * | 2016-12-14 | 2021-06-03 | Otsuka Pharmaceutical Factory, Inc. | Mammalian cell cryopreservation liquid |
CA3055761A1 (en) | 2017-03-30 | 2018-10-04 | Wake Forest University Health Sciences | Methods of treatment for kidney disease |
WO2019045049A1 (ja) * | 2017-09-01 | 2019-03-07 | 学校法人帝京大学 | 腎尿細管細胞特異的発現ベクター |
US20210024896A1 (en) * | 2018-03-28 | 2021-01-28 | Osaka University | Method for producing stem cell-derived lacrimal gland tissue |
US11331333B2 (en) | 2019-11-08 | 2022-05-17 | Georg-August-Universität Göttingen Stiftung Öffentichen Rechts, Universitätsmadizin | Treatment of aberrant fibroblast proliferation |
Family Cites Families (27)
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FR2646438B1 (fr) | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
US5574205A (en) | 1989-07-25 | 1996-11-12 | Cell Genesys | Homologous recombination for universal donor cells and chimeric mammalian hosts |
US5612205A (en) | 1990-08-29 | 1997-03-18 | Genpharm International, Incorporated | Homologous recombination in mammalian cells |
US5342761A (en) * | 1990-10-01 | 1994-08-30 | Research Development Foundation | Oncofetal gene, gene product and uses therefor |
US5286632A (en) * | 1991-01-09 | 1994-02-15 | Jones Douglas H | Method for in vivo recombination and mutagenesis |
WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
US5355699A (en) * | 1992-04-16 | 1994-10-18 | Tsudakoma Kogyo Kabushiki Kaisha | Flat knitting machine and a method of operating the rocking sinkers of the flat knitting machine |
US5320962A (en) * | 1992-07-22 | 1994-06-14 | Duke University | DNA encoding the human A1 adenosine receptor |
JPH11313675A (ja) * | 1998-04-30 | 1999-11-16 | Hoechst Marion Roussel Kk | ヒトbmp−7プロモーターおよびこれを用いた骨関連物質の探索法 |
US6355699B1 (en) | 1999-06-30 | 2002-03-12 | Ethicon, Inc. | Process for manufacturing biomedical foams |
US6759039B2 (en) * | 2000-06-30 | 2004-07-06 | Amcyte, Inc. | Culturing pancreatic stem cells having a specified, intermediate stage of development |
WO2002061053A1 (en) * | 2001-01-31 | 2002-08-08 | The General Hospital Corporation | Renal stem cells and uses thereof |
US6458588B1 (en) * | 2001-01-31 | 2002-10-01 | The General Hospital Corporation | Renal stem cells and uses thereof |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
PL1641914T3 (pl) | 2003-06-27 | 2017-01-31 | DePuy Synthes Products, Inc. | Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek |
EP1660644A1 (en) * | 2003-08-29 | 2006-05-31 | Regents Of The University Of Minnesota | Kidney derived stem cells and methods for their isolation, differentiation and use |
US8039258B2 (en) | 2004-09-28 | 2011-10-18 | Ethicon, Inc. | Tissue-engineering scaffolds containing self-assembled-peptide hydrogels |
US20060153815A1 (en) | 2004-12-21 | 2006-07-13 | Agnieszka Seyda | Tissue engineering devices for the repair and regeneration of tissue |
US20060171930A1 (en) | 2004-12-21 | 2006-08-03 | Agnieszka Seyda | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
WO2006083394A2 (en) | 2004-12-21 | 2006-08-10 | Ethicon, Inc. | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
PL1835924T3 (pl) | 2004-12-23 | 2014-01-31 | Ethicon Incorporated | Leczenie choroby Parkinsona i zaburzeń związanych z tą chorobą z użyciem komórek uzyskiwanych po porodzie |
ES2621847T3 (es) | 2004-12-23 | 2017-07-05 | DePuy Synthes Products, Inc. | Células posparto derivadas de tejido de cordón umbilical, y métodos de elaboración y uso de las mismas |
EP1971681B1 (en) | 2005-12-16 | 2017-08-23 | DePuy Synthes Products, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
US8741638B2 (en) | 2005-12-19 | 2014-06-03 | DePuy Synthes Products, LLC | In vitro expansion of postpartum-derived cells in roller bottles |
AU2006330409B2 (en) | 2005-12-28 | 2012-07-19 | Ethicon, Incorporated | Treatment of peripheral vascular disease using postpartum-derived cells |
PT2078073E (pt) | 2006-10-12 | 2013-11-11 | Ethicon Inc | Células derivadas do rim e métodos de utilização na reparação e regeneração de tecidos |
ES2524443T3 (es) | 2006-11-13 | 2014-12-09 | DePuy Synthes Products, LLC | Expansión in vitro de células postparto usando microportadores |
-
2007
- 2007-10-11 PT PT78526514T patent/PT2078073E/pt unknown
- 2007-10-11 US US11/871,045 patent/US10500230B2/en not_active Expired - Fee Related
- 2007-10-11 CN CN200780045631.3A patent/CN101595212B/zh not_active Expired - Fee Related
- 2007-10-11 CA CA2673521A patent/CA2673521C/en not_active Expired - Fee Related
- 2007-10-11 JP JP2009532404A patent/JP5450072B2/ja not_active Expired - Fee Related
- 2007-10-11 PL PL07852651T patent/PL2078073T3/pl unknown
- 2007-10-11 ES ES07852651T patent/ES2432395T3/es active Active
- 2007-10-11 AU AU2007308168A patent/AU2007308168B2/en not_active Ceased
- 2007-10-11 SI SI200731339T patent/SI2078073T1/sl unknown
- 2007-10-11 WO PCT/US2007/021708 patent/WO2008045498A1/en active Application Filing
- 2007-10-11 DK DK07852651.4T patent/DK2078073T3/da active
- 2007-10-11 EP EP07852651.4A patent/EP2078073B1/en active Active
-
2016
- 2016-08-17 US US15/238,993 patent/US10413571B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US10500230B2 (en) | 2019-12-10 |
CN101595212A (zh) | 2009-12-02 |
SI2078073T1 (sl) | 2013-11-29 |
WO2008045498A1 (en) | 2008-04-17 |
PL2078073T3 (pl) | 2013-12-31 |
ES2432395T3 (es) | 2013-12-03 |
PT2078073E (pt) | 2013-11-11 |
CA2673521A1 (en) | 2008-04-17 |
AU2007308168B2 (en) | 2013-09-26 |
EP2078073B1 (en) | 2013-07-24 |
US20080112939A1 (en) | 2008-05-15 |
US20160375062A1 (en) | 2016-12-29 |
AU2007308168A1 (en) | 2008-04-17 |
JP2010506563A (ja) | 2010-03-04 |
CA2673521C (en) | 2017-01-17 |
CN101595212B (zh) | 2014-04-30 |
US10413571B2 (en) | 2019-09-17 |
JP5450072B2 (ja) | 2014-03-26 |
EP2078073A1 (en) | 2009-07-15 |
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