PT1032557E - Processo de preparacao de derivados de bromometil-bifenilo - Google Patents

Processo de preparacao de derivados de bromometil-bifenilo

Info

Publication number
PT1032557E
PT1032557E PT98954537T PT98954537T PT1032557E PT 1032557 E PT1032557 E PT 1032557E PT 98954537 T PT98954537 T PT 98954537T PT 98954537 T PT98954537 T PT 98954537T PT 1032557 E PT1032557 E PT 1032557E
Authority
PT
Portugal
Prior art keywords
bromymethyl
preparation process
biphenyl derivatives
formula
biphenyl
Prior art date
Application number
PT98954537T
Other languages
English (en)
Inventor
Bertrand Castro
Michel Biard
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of PT1032557E publication Critical patent/PT1032557E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT98954537T 1997-11-17 1998-11-09 Processo de preparacao de derivados de bromometil-bifenilo PT1032557E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714376A FR2771090B1 (fr) 1997-11-17 1997-11-17 Procede de preparation de derives de bromomethyl-biphenyle

Publications (1)

Publication Number Publication Date
PT1032557E true PT1032557E (pt) 2004-02-27

Family

ID=9513439

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98954537T PT1032557E (pt) 1997-11-17 1998-11-09 Processo de preparacao de derivados de bromometil-bifenilo

Country Status (15)

Country Link
US (1) US6214999B1 (pt)
EP (1) EP1032557B1 (pt)
JP (1) JP4546642B2 (pt)
AT (1) ATE249424T1 (pt)
AU (1) AU1160899A (pt)
BR (1) BR9814651B1 (pt)
CA (1) CA2310324C (pt)
DE (1) DE69818091T2 (pt)
DK (1) DK1032557T5 (pt)
ES (1) ES2207004T3 (pt)
FR (1) FR2771090B1 (pt)
HU (1) HU228640B1 (pt)
NO (1) NO327836B1 (pt)
PT (1) PT1032557E (pt)
WO (1) WO1999025681A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60225486T2 (de) * 2002-06-12 2009-04-02 Sumitomo Chemical Co., Ltd. Verfahren zur herstellung von 4'-brommethyl-2-cyanobiphenyl
US7641181B2 (en) * 2003-01-24 2010-01-05 Liquid Spring Technologies, Inc. Distributed power suspension system
WO2004103947A1 (ja) * 2003-05-20 2004-12-02 Sumitomo Chemical Company, Limited ブロモメチル置換芳香族カルボン酸エステル化合物の製造方法
US7528258B2 (en) * 2004-09-02 2009-05-05 Teva Pharmaceutical Industries Ltd Preparation of olmesartan medoxomil
US20070054948A1 (en) * 2004-09-02 2007-03-08 Lilach Hedvati Purification of olmesartan medoxomil
US20060074117A1 (en) * 2004-09-02 2006-04-06 Lilach Hedvati Purification of olmesartan medoxomil
JP2008503595A (ja) * 2004-10-15 2008-02-07 テバ ファーマシューティカル インダストリーズ リミティド テルミサルタンの調製方法
JP2007525504A (ja) * 2004-12-30 2007-09-06 テバ ファーマシューティカル インダストリーズ リミティド 2.5よりも高いpHでオルメサルタンメドキソミルを調製するための方法
WO2006073519A1 (en) * 2005-01-03 2006-07-13 Teva Pharmaceutical Industries Ltd. Olmesartan medoxomil with reduced levels of impurities
US20060258727A1 (en) * 2005-01-03 2006-11-16 Lilach Hedvati Olmesartan medoxomil with reduced levels of impurities
WO2008078340A1 (en) * 2006-12-27 2008-07-03 Calyx Chemicals And Pharmaceuticals Ltd. Process for the separation of 4-bromomethyl-2'-substituted biphenyls from 4,4,-dibromomethyl-2'-substituted biphenyls
HUP0900788A2 (en) * 2009-12-16 2011-11-28 Sanofi Aventis Process for producing 4-bromomethyl-biphenyl derivatives
CN105399627A (zh) * 2015-10-22 2016-03-16 威特(湖南)药业有限公司 4’-溴甲基联苯-2-羧酸酯的合成方法
AU2017239816B9 (en) * 2016-03-31 2020-09-24 Fujifilm Corporation Method for producing 5-(bromomethyl)-1-benzothiophene
CN108164434A (zh) * 2017-12-27 2018-06-15 安徽太主科技发展有限公司 一种低成本4′-溴甲基-2-氰基联苯的制备方法
CN113816874B (zh) * 2021-10-30 2024-01-26 大连双硼医药化工有限公司 一种合成4-氰基-2-氟苄醇的工艺方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806584D0 (en) * 1988-03-19 1988-04-20 Interox Chemicals Ltd Bromination
JPH06298683A (ja) * 1993-04-15 1994-10-25 Sankyo Co Ltd 光反応による4−(2−置換)フェニルベンジルブロミド類の製造法
JPH0859515A (ja) * 1994-08-12 1996-03-05 Sanko Kagaku Kogyo Kk モノブロモメチル化芳香族化合物の製造方法
JP2928982B2 (ja) * 1994-10-27 1999-08-03 住化ファインケム株式会社 4’−ブロモメチル−2−シアノビフェニルの製造法
IT1291551B1 (it) * 1997-04-11 1999-01-11 Luso Farmaco Inst Processo per la preparazione di composti 4-bromometil bifenilici

Also Published As

Publication number Publication date
NO327836B1 (no) 2009-10-05
DE69818091D1 (de) 2003-10-16
EP1032557B1 (fr) 2003-09-10
EP1032557A1 (fr) 2000-09-06
DK1032557T5 (da) 2004-03-08
AU1160899A (en) 1999-06-07
BR9814651A (pt) 2000-10-03
CA2310324C (en) 2010-01-26
DK1032557T3 (da) 2004-01-19
HUP0004251A3 (en) 2003-05-28
JP2001523658A (ja) 2001-11-27
DE69818091T2 (de) 2004-07-01
FR2771090B1 (fr) 2000-02-04
NO20002530L (no) 2000-07-17
ES2207004T3 (es) 2004-05-16
WO1999025681A1 (fr) 1999-05-27
BR9814651B1 (pt) 2010-12-14
US6214999B1 (en) 2001-04-10
HU228640B1 (en) 2013-04-29
HUP0004251A2 (hu) 2001-04-28
FR2771090A1 (fr) 1999-05-21
JP4546642B2 (ja) 2010-09-15
CA2310324A1 (en) 1999-05-27
NO20002530D0 (no) 2000-05-16
ATE249424T1 (de) 2003-09-15

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