IT1301977B1 - Procedimento per la preparazione di r-(-)-carnitina - Google Patents
Procedimento per la preparazione di r-(-)-carnitinaInfo
- Publication number
- IT1301977B1 IT1301977B1 IT1998MI001796A ITMI981796A IT1301977B1 IT 1301977 B1 IT1301977 B1 IT 1301977B1 IT 1998MI001796 A IT1998MI001796 A IT 1998MI001796A IT MI981796 A ITMI981796 A IT MI981796A IT 1301977 B1 IT1301977 B1 IT 1301977B1
- Authority
- IT
- Italy
- Prior art keywords
- yield
- compound
- conversion
- carnitine
- cyano
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Luminescent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI001796A IT1301977B1 (it) | 1998-07-31 | 1998-07-31 | Procedimento per la preparazione di r-(-)-carnitina |
AT99936972T ATE225329T1 (de) | 1998-07-31 | 1999-07-27 | Verfahren zur herstellung von r-(-)-carnitin |
KR1020017000539A KR100614545B1 (ko) | 1998-07-31 | 1999-07-27 | R-(-)-카르니틴의 제조 방법 |
JP2000562339A JP2002521469A (ja) | 1998-07-31 | 1999-07-27 | R−(−)−カルニチンの調製法 |
DE69903320T DE69903320T2 (de) | 1998-07-31 | 1999-07-27 | Verfahren zur herstellung von r-(-)-carnitin |
PCT/IT1999/000241 WO2000006532A2 (en) | 1998-07-31 | 1999-07-27 | Process for the preparation of r-(-)-carnitine |
ES99936972T ES2184488T3 (es) | 1998-07-31 | 1999-07-27 | Procedimiento para la preparacion r-(-)-carnitina'. |
EP99936972A EP1100768B1 (en) | 1998-07-31 | 1999-07-27 | Process for the preparation of r-(-)-carnitine |
DK99936972T DK1100768T3 (da) | 1998-07-31 | 1999-07-27 | Fremgangsmåde til fremstilling af R-(-)-carnitin |
PT99936972T PT1100768E (pt) | 1998-07-31 | 1999-07-27 | Processo para a preparacao de r-(-)-carnitina |
AU51934/99A AU5193499A (en) | 1998-07-31 | 1999-07-27 | Process for the preparation of r-(-)-carnitine |
US09/740,806 US6316667B2 (en) | 1998-07-31 | 2000-12-21 | Process for the preparation of R-(-)-carnitine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998MI001796A IT1301977B1 (it) | 1998-07-31 | 1998-07-31 | Procedimento per la preparazione di r-(-)-carnitina |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI981796A0 ITMI981796A0 (it) | 1998-07-31 |
ITMI981796A1 ITMI981796A1 (it) | 2000-01-31 |
IT1301977B1 true IT1301977B1 (it) | 2000-07-20 |
Family
ID=11380580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT1998MI001796A IT1301977B1 (it) | 1998-07-31 | 1998-07-31 | Procedimento per la preparazione di r-(-)-carnitina |
Country Status (12)
Country | Link |
---|---|
US (1) | US6316667B2 (it) |
EP (1) | EP1100768B1 (it) |
JP (1) | JP2002521469A (it) |
KR (1) | KR100614545B1 (it) |
AT (1) | ATE225329T1 (it) |
AU (1) | AU5193499A (it) |
DE (1) | DE69903320T2 (it) |
DK (1) | DK1100768T3 (it) |
ES (1) | ES2184488T3 (it) |
IT (1) | IT1301977B1 (it) |
PT (1) | PT1100768E (it) |
WO (1) | WO2000006532A2 (it) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6288239B1 (en) * | 2000-09-19 | 2001-09-11 | Board Of Trustees Operating Michigan State University | 5-trityloxymethyl-oxazolidinones and process for the preparation thereof |
KR101108115B1 (ko) * | 2002-08-06 | 2012-01-31 | 파마셋 인코포레이티드 | 1,3-디옥솔란 뉴클레오사이드의 제조 방법 |
CN100335457C (zh) * | 2005-09-08 | 2007-09-05 | 上海交通大学 | 3-位手性羟基被保护的3,4-二羟基丁酸酯及其制备方法 |
KR100846673B1 (ko) | 2006-03-22 | 2008-07-16 | 엔자이텍 주식회사 | 엘-카르니틴의 제조방법 |
CN105801572B (zh) * | 2016-05-12 | 2018-11-06 | 山东罗欣药业集团恒欣药业有限公司 | 一种利伐沙班的制备方法 |
CN106749073B (zh) * | 2016-11-08 | 2019-06-18 | 山东裕欣药业有限公司 | 一种利奈唑胺的制备方法 |
CN116655481B (zh) * | 2023-06-14 | 2023-11-28 | 海南卓科制药有限公司 | 一种工业化合成左卡尼汀的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2710688B2 (ja) * | 1990-10-09 | 1998-02-10 | 鐘淵化学工業株式会社 | 4―ブロモ―3―ヒドロキシ酪酸エステル誘導体の製造法 |
IT1256705B (it) * | 1992-12-21 | 1995-12-12 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
US5473104A (en) * | 1994-09-13 | 1995-12-05 | Neurocrine Biosciences, Inc. | Process for the preparation of L-carnitine |
-
1998
- 1998-07-31 IT IT1998MI001796A patent/IT1301977B1/it active IP Right Grant
-
1999
- 1999-07-27 PT PT99936972T patent/PT1100768E/pt unknown
- 1999-07-27 DK DK99936972T patent/DK1100768T3/da active
- 1999-07-27 ES ES99936972T patent/ES2184488T3/es not_active Expired - Lifetime
- 1999-07-27 KR KR1020017000539A patent/KR100614545B1/ko not_active IP Right Cessation
- 1999-07-27 AU AU51934/99A patent/AU5193499A/en not_active Abandoned
- 1999-07-27 WO PCT/IT1999/000241 patent/WO2000006532A2/en active IP Right Grant
- 1999-07-27 AT AT99936972T patent/ATE225329T1/de not_active IP Right Cessation
- 1999-07-27 EP EP99936972A patent/EP1100768B1/en not_active Expired - Lifetime
- 1999-07-27 JP JP2000562339A patent/JP2002521469A/ja active Pending
- 1999-07-27 DE DE69903320T patent/DE69903320T2/de not_active Expired - Fee Related
-
2000
- 2000-12-21 US US09/740,806 patent/US6316667B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ITMI981796A0 (it) | 1998-07-31 |
US20010031892A1 (en) | 2001-10-18 |
WO2000006532A3 (en) | 2000-05-11 |
DE69903320T2 (de) | 2003-06-18 |
ITMI981796A1 (it) | 2000-01-31 |
DK1100768T3 (da) | 2003-02-03 |
KR20010071884A (ko) | 2001-07-31 |
PT1100768E (pt) | 2003-02-28 |
DE69903320D1 (de) | 2002-11-07 |
ES2184488T3 (es) | 2003-04-01 |
KR100614545B1 (ko) | 2006-08-25 |
EP1100768A2 (en) | 2001-05-23 |
JP2002521469A (ja) | 2002-07-16 |
US6316667B2 (en) | 2001-11-13 |
AU5193499A (en) | 2000-02-21 |
EP1100768B1 (en) | 2002-10-02 |
ATE225329T1 (de) | 2002-10-15 |
WO2000006532A2 (en) | 2000-02-10 |
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Legal Events
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0001 | Granted |