IT1256705B - Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. - Google Patents
Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.Info
- Publication number
- IT1256705B IT1256705B ITRM920915A ITRM920915A IT1256705B IT 1256705 B IT1256705 B IT 1256705B IT RM920915 A ITRM920915 A IT RM920915A IT RM920915 A ITRM920915 A IT RM920915A IT 1256705 B IT1256705 B IT 1256705B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- procedure
- preparation
- waste product
- opposite configuration
- Prior art date
Links
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002699 waste material Substances 0.000 title abstract 2
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
- -1 acyl D - (+) - carnitine ester Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
- C07D305/12—Beta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Processing Of Solid Wastes (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Procedimento per produrre L-(-)-carnitina dal composto di scarto D-(+)-carnitinammide, consistente nel convertire la D-(+)-carnitinammide in D-(+)-carnitina, questa in un estere che viene acilato con un agente acilante che introduce un gruppo uscente fornendo un estere di acil D-(+)-carnitina che, una volta ripristinata la funzione carbossilica, per trattamento in ambiente basico dà L-(-)carnitina.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920915A IT1256705B (it) | 1992-12-21 | 1992-12-21 | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
ZA939444A ZA939444B (en) | 1992-12-21 | 1993-03-28 | Process for manfacturing L-(-) carnitine from a waste product having opposite configuration. |
DK93830506.7T DK0609643T3 (da) | 1992-12-21 | 1993-12-15 | Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration |
EP93830506A EP0609643B1 (en) | 1992-12-21 | 1993-12-15 | Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration |
DE69303807T DE69303807T2 (de) | 1992-12-21 | 1993-12-15 | Verfahren zur Herstellung einer L-(-)Carnitin aus einem Abfallprodukt mit der gegengesetzter Konfiguration |
ES93830506T ES2090945T3 (es) | 1992-12-21 | 1993-12-15 | Procedimiento para la preparacion de l-(-)-carnitina a partir de un producto de desecho que tiene configuracion opuesta. |
AT93830506T ATE140694T1 (de) | 1992-12-21 | 1993-12-15 | Verfahren zur herstellung einer l-(-)carnitin aus einem abfallprodukt mit der gegengesetzter konfiguration |
KR1019930028618A KR100294780B1 (ko) | 1992-12-21 | 1993-12-20 | 반대배치를갖는폐물질로부터l-(-)-카르니틴의제조방법 |
CA002111898A CA2111898C (en) | 1992-12-21 | 1993-12-20 | Process for manufacturing l-(-)-carnitine from a waste product having opposite configuration |
JP31979293A JP3502649B2 (ja) | 1992-12-21 | 1993-12-20 | 配置異性体副産物からのl−(−)−カルニチンの製造方法 |
US08/170,764 US5412113A (en) | 1992-12-21 | 1993-12-21 | Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration |
US08/367,863 US5599978A (en) | 1992-12-21 | 1995-01-03 | Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration |
GR960401768T GR3020617T3 (en) | 1992-12-21 | 1996-07-25 | Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration. |
HK98104936A HK1005861A1 (en) | 1992-12-21 | 1998-06-05 | Process for manufacturing l-(-)-carnitine from a waste product having opposite configuration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920915A IT1256705B (it) | 1992-12-21 | 1992-12-21 | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM920915A0 ITRM920915A0 (it) | 1992-12-21 |
ITRM920915A1 ITRM920915A1 (it) | 1994-06-21 |
IT1256705B true IT1256705B (it) | 1995-12-12 |
Family
ID=11401346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM920915A IT1256705B (it) | 1992-12-21 | 1992-12-21 | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5412113A (it) |
EP (1) | EP0609643B1 (it) |
JP (1) | JP3502649B2 (it) |
KR (1) | KR100294780B1 (it) |
AT (1) | ATE140694T1 (it) |
CA (1) | CA2111898C (it) |
DE (1) | DE69303807T2 (it) |
DK (1) | DK0609643T3 (it) |
ES (1) | ES2090945T3 (it) |
GR (1) | GR3020617T3 (it) |
HK (1) | HK1005861A1 (it) |
IT (1) | IT1256705B (it) |
ZA (1) | ZA939444B (it) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1240760B (it) * | 1990-02-12 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma. |
IT1261230B (it) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione. |
IT1261828B (it) | 1993-07-14 | 1996-06-03 | Sigma Tau Ind Farmaceuti | Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico. |
IT1276207B1 (it) * | 1995-09-29 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone |
IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
IT1299182B1 (it) | 1998-05-29 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Procedimento chimico per la sintesi stereoselettiva della r-(-)- carnitina. |
IT1301977B1 (it) * | 1998-07-31 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di r-(-)-carnitina |
IT1307303B1 (it) | 1999-12-23 | 2001-10-30 | Sigma Tau Ind Farmaceuti | Idrolisi stereospecifica di esteri otticamente attivi. |
IT1306184B1 (it) | 1999-08-05 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Nitrilossi derivati della (r) e (s)-carnitina. |
JP2003508488A (ja) * | 1999-09-03 | 2003-03-04 | シグマ−タウ・ヘルスサイエンス・ソシエタ・ペル・アチオニ | 超微細l−カルニチン、その調製方法、それを含む組成物、及びその使用方法 |
DE10027393B4 (de) * | 2000-06-02 | 2007-05-16 | Wella Ag | Poly- und Oligoester kationischer Hydroxysäuren, Verfahren zu ihrer Herstellung und ihre Verwendung |
KR20130093078A (ko) * | 2010-07-21 | 2013-08-21 | 론차리미티드 | 베타-락톤으로부터 카르니틴의 제조방법 |
BR112016030983A8 (pt) | 2014-07-03 | 2021-07-06 | Nan Global Llc | composições para o tratamento de obesidade, prevenção de ganho de peso, promoção de perda de peso, promoção de emagrecimento, ou tratamento de ou prevenção do desenvolvimento de diabetes, kit, método para a preparação de tirfostina 9 e uso |
CN115057789B (zh) * | 2022-06-30 | 2024-04-02 | 中科萱嘉医养(珠海)健康科技有限公司 | 一种左旋肉碱离子液体及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1156852B (it) * | 1978-07-10 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni |
IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
US5200526A (en) * | 1987-04-27 | 1993-04-06 | The Governors Of The University Of Alberta | Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts |
-
1992
- 1992-12-21 IT ITRM920915A patent/IT1256705B/it active IP Right Grant
-
1993
- 1993-03-28 ZA ZA939444A patent/ZA939444B/xx unknown
- 1993-12-15 DE DE69303807T patent/DE69303807T2/de not_active Expired - Lifetime
- 1993-12-15 DK DK93830506.7T patent/DK0609643T3/da active
- 1993-12-15 EP EP93830506A patent/EP0609643B1/en not_active Expired - Lifetime
- 1993-12-15 ES ES93830506T patent/ES2090945T3/es not_active Expired - Lifetime
- 1993-12-15 AT AT93830506T patent/ATE140694T1/de not_active IP Right Cessation
- 1993-12-20 KR KR1019930028618A patent/KR100294780B1/ko not_active IP Right Cessation
- 1993-12-20 JP JP31979293A patent/JP3502649B2/ja not_active Expired - Fee Related
- 1993-12-20 CA CA002111898A patent/CA2111898C/en not_active Expired - Fee Related
- 1993-12-21 US US08/170,764 patent/US5412113A/en not_active Expired - Lifetime
-
1995
- 1995-01-03 US US08/367,863 patent/US5599978A/en not_active Expired - Lifetime
-
1996
- 1996-07-25 GR GR960401768T patent/GR3020617T3/el unknown
-
1998
- 1998-06-05 HK HK98104936A patent/HK1005861A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ITRM920915A1 (it) | 1994-06-21 |
DE69303807T2 (de) | 1996-11-28 |
CA2111898C (en) | 2004-04-27 |
GR3020617T3 (en) | 1996-10-31 |
DE69303807D1 (de) | 1996-08-29 |
JPH06199751A (ja) | 1994-07-19 |
HK1005861A1 (en) | 1999-01-29 |
CA2111898A1 (en) | 1994-06-22 |
ATE140694T1 (de) | 1996-08-15 |
DK0609643T3 (da) | 1996-11-11 |
US5599978A (en) | 1997-02-04 |
KR940014303A (ko) | 1994-07-18 |
EP0609643A1 (en) | 1994-08-10 |
ES2090945T3 (es) | 1996-10-16 |
ZA939444B (en) | 1994-08-09 |
EP0609643B1 (en) | 1996-07-24 |
US5412113A (en) | 1995-05-02 |
KR100294780B1 (ko) | 2001-09-17 |
ITRM920915A0 (it) | 1992-12-21 |
JP3502649B2 (ja) | 2004-03-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT1256705B (it) | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. | |
IL184321A0 (en) | Process for selective derivatization of taxanes | |
DE69402043T2 (de) | Verfahrenshilfsmittel für gaserzeugende Zusammensetzungen | |
EP0823475A4 (en) | HIGH UNSATURATED FATTY ACID PRODUCING MICROORGANISMS AND METHOD FOR PRODUCING HIGH UNSATURATED FATTY ACIDS BY USING THESE MICROORGANISMS | |
CA2157114A1 (en) | Process for the preparation of 9-desoxotaxanes | |
HUT60299A (en) | Process for producing alkenyl succinimides and their application as lubricant additive | |
GB2300052B (en) | Method of generating die structure data | |
SG47179A1 (en) | Computerized music apparatus processing waveform to create sound effect | |
AR013080A2 (es) | Acil transferasa purificada | |
DK1021433T3 (da) | Fremgangsmåde til fremstilling af naturlige 1,3-diolderivater og tilsvarende naturlige 1,3-dioxanderivater | |
IT1261489B (it) | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. | |
ITMI910930A0 (it) | Metodo per la produzione di parti di motori elettrici e motori utilizzanti parti prodotte con detto metodo | |
CA2120811A1 (en) | Improved process for manufacturing l-(-)-carnitine from waste products having opposite configuration | |
FI973215A0 (fi) | Menetelmä pelkistävien sokereiden hajottamiseksi emäksisen hapetuksen avulla ja näin saadut tuotteet | |
IT1261231B (it) | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. | |
FR2707813B1 (fr) | Rotor de magnéto-générateur et procédé pour sa fabrication. | |
GB9711551D0 (en) | Method of generating die structure data | |
MC1638A1 (fr) | Antibiotiques nouveaux | |
AR247215A1 (es) | Un procedimiento para producir un antibiotico antifungico y antiviral, n-acetilbenanomicina b. | |
TW377341B (en) | Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration | |
ES8300328A1 (es) | Procedimiento para preparar acidos furanil y tienil acrili- cos acilados | |
UA15182A (uk) | Спосіб моделюваhhя пародоhтиту | |
AU8521991A (en) | Method of producing metal soap | |
IT1254299B (it) | Procedimento per la produzione di energia meccanica da fonti rinnovabili e impianto per la realizzazione di detto procedimento. | |
UA9518A (uk) | Спосіб оперативного регулювання часу реверберації звуку в приміщеннях (варіанти) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19951113 |