ATE225329T1 - Verfahren zur herstellung von r-(-)-carnitin - Google Patents

Verfahren zur herstellung von r-(-)-carnitin

Info

Publication number
ATE225329T1
ATE225329T1 AT99936972T AT99936972T ATE225329T1 AT E225329 T1 ATE225329 T1 AT E225329T1 AT 99936972 T AT99936972 T AT 99936972T AT 99936972 T AT99936972 T AT 99936972T AT E225329 T1 ATE225329 T1 AT E225329T1
Authority
AT
Austria
Prior art keywords
yield
compound
carnitine
conversion
cyano
Prior art date
Application number
AT99936972T
Other languages
English (en)
Inventor
Fabio Giannessi
Maria Ornella Tinti
Angelis Francesco De
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE225329T1 publication Critical patent/ATE225329T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT99936972T 1998-07-31 1999-07-27 Verfahren zur herstellung von r-(-)-carnitin ATE225329T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001796A IT1301977B1 (it) 1998-07-31 1998-07-31 Procedimento per la preparazione di r-(-)-carnitina
PCT/IT1999/000241 WO2000006532A2 (en) 1998-07-31 1999-07-27 Process for the preparation of r-(-)-carnitine

Publications (1)

Publication Number Publication Date
ATE225329T1 true ATE225329T1 (de) 2002-10-15

Family

ID=11380580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99936972T ATE225329T1 (de) 1998-07-31 1999-07-27 Verfahren zur herstellung von r-(-)-carnitin

Country Status (12)

Country Link
US (1) US6316667B2 (de)
EP (1) EP1100768B1 (de)
JP (1) JP2002521469A (de)
KR (1) KR100614545B1 (de)
AT (1) ATE225329T1 (de)
AU (1) AU5193499A (de)
DE (1) DE69903320T2 (de)
DK (1) DK1100768T3 (de)
ES (1) ES2184488T3 (de)
IT (1) IT1301977B1 (de)
PT (1) PT1100768E (de)
WO (1) WO2000006532A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6288239B1 (en) * 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
US6855821B2 (en) * 2002-08-06 2005-02-15 Pharmasset, Ltd. Processes for preparing 1,3-dioxolane nucleosides
CN100335457C (zh) * 2005-09-08 2007-09-05 上海交通大学 3－位手性羟基被保护的3，4－二羟基丁酸酯及其制备方法
KR100846673B1 (ko) 2006-03-22 2008-07-16 엔자이텍 주식회사 엘-카르니틴의 제조방법
CN105801572B (zh) * 2016-05-12 2018-11-06 山东罗欣药业集团恒欣药业有限公司 一种利伐沙班的制备方法
CN106749073B (zh) * 2016-11-08 2019-06-18 山东裕欣药业有限公司 一种利奈唑胺的制备方法
CN116655481B (zh) * 2023-06-14 2023-11-28 海南卓科制药有限公司 一种工业化合成左卡尼汀的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2710688B2 (ja) * 1990-10-09 1998-02-10 鐘淵化学工業株式会社 ４―ブロモ―３―ヒドロキシ酪酸エステル誘導体の製造法
IT1256705B (it) * 1992-12-21 1995-12-12 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
US5473104A (en) * 1994-09-13 1995-12-05 Neurocrine Biosciences, Inc. Process for the preparation of L-carnitine

Also Published As

Publication number Publication date
ITMI981796A1 (it) 2000-01-31
DK1100768T3 (da) 2003-02-03
WO2000006532A3 (en) 2000-05-11
PT1100768E (pt) 2003-02-28
DE69903320D1 (de) 2002-11-07
JP2002521469A (ja) 2002-07-16
KR100614545B1 (ko) 2006-08-25
KR20010071884A (ko) 2001-07-31
EP1100768A2 (de) 2001-05-23
ITMI981796A0 (it) 1998-07-31
US20010031892A1 (en) 2001-10-18
WO2000006532A2 (en) 2000-02-10
AU5193499A (en) 2000-02-21
US6316667B2 (en) 2001-11-13
IT1301977B1 (it) 2000-07-20
ES2184488T3 (es) 2003-04-01
EP1100768B1 (de) 2002-10-02
DE69903320T2 (de) 2003-06-18

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