PL387118A1 - Kapsułki do inhalacji zawierające tiotropium i ich zastosowanie - Google Patents

Kapsułki do inhalacji zawierające tiotropium i ich zastosowanie

Info

Publication number
PL387118A1
PL387118A1 PL387118A PL38711802A PL387118A1 PL 387118 A1 PL387118 A1 PL 387118A1 PL 387118 A PL387118 A PL 387118A PL 38711802 A PL38711802 A PL 38711802A PL 387118 A1 PL387118 A1 PL 387118A1
Authority
PL
Poland
Prior art keywords
tiotropium
inhalation capsules
inhalation
capsules
Prior art date
Application number
PL387118A
Other languages
English (en)
Other versions
PL205714B1 (pl
Inventor
Dieter Hochrainer
Michael Trunk
Karoline Bechtold-Peters
Michael Waltz
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7687020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL387118(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg
Publication of PL387118A1 publication Critical patent/PL387118A1/pl
Publication of PL205714B1 publication Critical patent/PL205714B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
PL387118A 2001-06-01 2002-05-27 Kapsułki do inhalacji zawierające tiotropium i ich zastosowanie PL205714B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10126924A DE10126924A1 (de) 2001-06-01 2001-06-01 Inhalationskapseln

Publications (2)

Publication Number Publication Date
PL387118A1 true PL387118A1 (pl) 2004-12-13
PL205714B1 PL205714B1 (pl) 2010-05-31

Family

ID=7687020

Family Applications (2)

Application Number Title Priority Date Filing Date
PL387118A PL205714B1 (pl) 2001-06-01 2002-05-27 Kapsułki do inhalacji zawierające tiotropium i ich zastosowanie
PL364108A PL203801B1 (pl) 2001-06-01 2002-05-27 Kapsułki do inhalacji, ich zastosowanie oraz sposób wytwarzania kapsułki

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL364108A PL203801B1 (pl) 2001-06-01 2002-05-27 Kapsułki do inhalacji, ich zastosowanie oraz sposób wytwarzania kapsułki

Country Status (37)

Country Link
EP (2) EP1508330A1 (pl)
JP (3) JP4447311B2 (pl)
KR (2) KR100921904B1 (pl)
CN (3) CN1512875A (pl)
AR (2) AR034346A1 (pl)
AT (1) ATE285752T1 (pl)
AU (2) AU2002344354B2 (pl)
BG (1) BG65655B1 (pl)
BR (1) BR0209366A (pl)
CA (1) CA2448425C (pl)
CH (1) CH1379220H1 (pl)
CO (1) CO5540379A2 (pl)
CZ (1) CZ300284B6 (pl)
DE (2) DE10126924A1 (pl)
EA (1) EA005188B1 (pl)
EC (2) ECSP034868A (pl)
EE (1) EE05416B1 (pl)
EG (1) EG24227A (pl)
ES (1) ES2236590B5 (pl)
HR (1) HRP20030993B1 (pl)
HU (3) HU231082B1 (pl)
IL (2) IL158917A0 (pl)
ME (1) ME00301B (pl)
MX (1) MXPA03010990A (pl)
MY (1) MY126253A (pl)
NO (1) NO332857B3 (pl)
NZ (1) NZ530356A (pl)
PE (1) PE20030071A1 (pl)
PL (2) PL205714B1 (pl)
PT (1) PT1379220E (pl)
RS (1) RS50353B (pl)
SI (1) SI1379220T1 (pl)
SK (2) SK287346B6 (pl)
TW (1) TWI327921B (pl)
UA (1) UA75659C2 (pl)
WO (1) WO2002098874A2 (pl)
ZA (1) ZA200308340B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226982B1 (en) 2000-10-12 2010-04-28 Boehringer Ingelheim Pharma Novel tiotropium-containing inhalation powder, process for its preperation and its use
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
DE10212264A1 (de) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
MXPA04010990A (es) * 2002-05-07 2005-02-14 Nektar Therapeutics Capsulas para inhaladores de polvo seco y metodo s para elaborarlas y utilizarlas.
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
DE10258360A1 (de) * 2002-12-12 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Kapselkammer zum Aufnehmen einer mit Wirkstoff gefüllten Einwegkapsel
DE10352277A1 (de) * 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
SE0303570L (sv) 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
GB0503738D0 (en) 2005-02-23 2005-03-30 Optinose As Powder delivery devices
US7694676B2 (en) 2005-04-22 2010-04-13 Boehringer Ingelheim Gmbh Dry powder inhaler
JP4825455B2 (ja) * 2005-05-02 2011-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 粉末吸入器
DE102006016901A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016904A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
GB0716026D0 (en) * 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007052871A1 (de) * 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen
JP2011512175A (ja) * 2008-02-08 2011-04-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング カプセル充填方法及び装置
EP2172190A1 (en) * 2008-10-02 2010-04-07 Laboratorios Liconsa, S.A. Inhalable particles comprising tiotropium
EP2400950B1 (en) 2009-02-26 2019-05-22 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
EP2411008B1 (en) * 2009-03-27 2017-03-22 Mahmut Bilgic Complexes of tiotropium with improved properties of solubility and stability
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2011152804A2 (en) 2010-06-03 2011-12-08 Mahmut Bilgic Process for dry powder formulations
DE202011102694U1 (de) 2011-06-29 2011-12-19 Zisser Gmbh Inhalationsgerät für Heimanwender
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
UA115989C2 (uk) 2012-07-05 2018-01-25 Арвен Айлак Санайі Ве Тіджарет А.С. Фармацевтична композиція для інгалятора сухого порошку, що містить антагоністи мускаринових рецепторів тривалої дії
DE202013000774U1 (de) 2013-01-21 2013-04-15 Rhinofilt GmbH Miniaturisiertes Inhalationsgerät zur Privatanwendung
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
CN108295042A (zh) * 2018-03-05 2018-07-20 上海祺宇生物科技有限公司 一种用于吸入药剂的植物空心胶囊及其胶囊剂
CN108451920A (zh) * 2018-03-14 2018-08-28 绍兴康可胶囊有限公司 一种吸雾式胶囊及其制备方法
CN114848605B (zh) * 2022-03-25 2023-08-11 上海方予健康医药科技有限公司 一种供吸入粉雾剂用的明胶胶囊

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US5626871A (en) * 1992-06-12 1997-05-06 Teijin Limited Preparation for intratracheobronchial administration
US6228394B1 (en) * 1997-10-14 2001-05-08 Boehringer Ingelheim Pharmaceuticals, Inc. Supercritical fluid extraction of mould lubricant from hard shell capsules
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
JP2000143502A (ja) * 1998-11-11 2000-05-23 Shionogi Qualicaps Kk 吸入製剤
EP2266548B1 (de) * 1998-11-13 2020-05-20 Jagotec AG Trockenpulver zur inhalation
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
EP1072258A1 (de) * 1999-07-28 2001-01-31 Greither, Peter Eine Kapsel für die Freisetzung von Bakterien, enthaltend ein Bakterienlyophilisat und ein Verfahren zu ihrer Herstellung
WO2001026630A1 (fr) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Preparations pour inhalation en poudre et leur procede de production
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln

Also Published As

Publication number Publication date
ZA200308340B (en) 2004-05-21
CZ20033579A3 (en) 2004-05-12
YU93503A (sh) 2006-05-25
SK287379B6 (sk) 2010-08-09
NO20035265L (no) 2003-11-27
NZ530356A (en) 2005-05-27
HU231082B1 (hu) 2020-06-29
CN101697965A (zh) 2010-04-28
MXPA03010990A (es) 2004-02-27
IL158917A (en) 2008-11-03
HRP20030993B1 (en) 2011-10-31
ECSP11004868A (es) 2011-02-28
ES2236590B5 (es) 2018-03-05
HUP1500188A2 (en) 2005-03-29
EA005188B1 (ru) 2004-12-30
EE05416B1 (et) 2011-06-15
DE10126924A1 (de) 2002-12-05
EP1508330A1 (de) 2005-02-23
MY126253A (en) 2006-09-29
HU230827B1 (hu) 2018-07-30
EA200301275A1 (ru) 2004-06-24
PE20030071A1 (es) 2003-03-04
PL364108A1 (pl) 2004-12-13
AU2008203057B2 (en) 2011-12-08
IL158917A0 (en) 2004-05-12
HUP0400666A3 (en) 2009-06-29
HUP0400666A2 (hu) 2005-03-29
HRP20030993A2 (en) 2005-08-31
KR100952321B1 (ko) 2010-04-09
SK16202003A3 (sk) 2004-05-04
PL205714B1 (pl) 2010-05-31
JP2008050364A (ja) 2008-03-06
EP1379220B1 (de) 2004-12-29
KR20040007638A (ko) 2004-01-24
MEP42508A (en) 2011-02-10
NO20035265D0 (no) 2003-11-27
AU2002344354B2 (en) 2008-08-07
BR0209366A (pt) 2004-06-08
ES2236590T3 (es) 2005-07-16
CZ300284B6 (cs) 2009-04-08
HU230058B1 (hu) 2015-06-29
KR100921904B1 (ko) 2009-10-16
TWI327921B (en) 2010-08-01
PT1379220E (pt) 2005-03-31
CA2448425C (en) 2010-12-21
BG108380A (en) 2004-11-30
NO332857B1 (no) 2013-01-21
ME00301B (me) 2011-05-10
EP1379220A2 (de) 2004-01-14
AR034346A1 (es) 2004-02-18
RS50353B (sr) 2009-11-10
AR084804A2 (es) 2013-06-26
KR20090010140A (ko) 2009-01-28
EE200300595A (et) 2004-02-16
AU2008203057C8 (en) 2017-04-06
JP4787034B2 (ja) 2011-10-05
WO2002098874A2 (de) 2002-12-12
CO5540379A2 (es) 2005-07-29
BG65655B1 (bg) 2009-05-29
JP2006143747A (ja) 2006-06-08
JP4447311B2 (ja) 2010-04-07
DE50201898D1 (de) 2005-02-03
PL203801B1 (pl) 2009-11-30
CN101829072A (zh) 2010-09-15
SK287346B6 (sk) 2010-07-07
UA75659C2 (en) 2006-05-15
CN1512875A (zh) 2004-07-14
AU2008203057C1 (en) 2017-05-18
SI1379220T1 (en) 2005-04-30
NO332857B3 (no) 2016-01-25
ATE285752T1 (de) 2005-01-15
JP2005500279A (ja) 2005-01-06
EG24227A (en) 2008-11-10
AU2008203057A1 (en) 2008-07-31
CH1379220H1 (pl) 2018-10-31
CA2448425A1 (en) 2002-12-12
ECSP034868A (es) 2004-03-23
WO2002098874A3 (de) 2003-09-12

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