PL372084A1 - Związek pochodnej 8-azaprostaglandyny i środek zawierający ten związek jako składnik aktywny - Google Patents
Związek pochodnej 8-azaprostaglandyny i środek zawierający ten związek jako składnik aktywnyInfo
- Publication number
- PL372084A1 PL372084A1 PL03372084A PL37208403A PL372084A1 PL 372084 A1 PL372084 A1 PL 372084A1 PL 03372084 A PL03372084 A PL 03372084A PL 37208403 A PL37208403 A PL 37208403A PL 372084 A1 PL372084 A1 PL 372084A1
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- active ingredient
- drugs containing
- azaprostaglandin derivative
- azaprostaglandin
- Prior art date
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002058487 | 2002-03-05 | ||
JP2002216567 | 2002-07-25 | ||
JP2003013447 | 2003-01-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
PL372084A1 true PL372084A1 (pl) | 2005-07-11 |
Family
ID=27792041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL03372084A PL372084A1 (pl) | 2002-03-05 | 2003-03-04 | Związek pochodnej 8-azaprostaglandyny i środek zawierający ten związek jako składnik aktywny |
Country Status (16)
Country | Link |
---|---|
US (3) | US7402605B2 (pl) |
EP (1) | EP1481976B1 (pl) |
JP (2) | JP4547912B2 (pl) |
KR (1) | KR100704215B1 (pl) |
CN (1) | CN1653046A (pl) |
AU (1) | AU2003211574A1 (pl) |
BR (1) | BR0308166A (pl) |
CA (1) | CA2477715A1 (pl) |
IL (1) | IL163866A0 (pl) |
MX (1) | MXPA04008596A (pl) |
NO (1) | NO20043702L (pl) |
NZ (1) | NZ535024A (pl) |
PL (1) | PL372084A1 (pl) |
RU (1) | RU2306309C2 (pl) |
TW (1) | TW200305425A (pl) |
WO (1) | WO2003074483A1 (pl) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1556347A4 (en) * | 2002-06-10 | 2006-08-09 | Applied Research Systems | GAMMA LACTAME AS PROSTAGLAND INAGONISTS AND THEIR USE |
CA2495917A1 (en) * | 2002-08-28 | 2004-03-11 | Merck Frosst Canada & Co. | Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma |
AU2003275838A1 (en) * | 2002-10-25 | 2004-05-13 | Beunard, Jean-Luc | Pyrrolidin-2-on derivatives as ep4 receptor agonists |
WO2004089411A1 (ja) * | 2003-04-03 | 2004-10-21 | Ono Pharmaceutical Co., Ltd. | 脊柱管狭窄症治療剤 |
EP2422814A1 (en) | 2003-07-25 | 2012-02-29 | Ono Pharmaceutical Co., Ltd. | Remedy for cartilage-related diseases |
EP1682127B1 (en) * | 2003-11-14 | 2009-07-29 | Vertex Pharmaceuticals Incorporated | Thiazoles and oxazoles useful as modulators of atp-binding cassette transporters |
US7833995B2 (en) | 2003-12-05 | 2010-11-16 | Ono Pharmaceutical Co., Ltd. | Blood flow promoters for cauda equina tissues |
WO2005072743A1 (ja) * | 2004-01-30 | 2005-08-11 | Ono Pharmaceutical Co., Ltd. | 気管支拡張剤 |
JP2006008568A (ja) * | 2004-06-24 | 2006-01-12 | Cyclochem:Kk | IgE抗体抑制剤および食品 |
US7858650B2 (en) | 2004-10-22 | 2010-12-28 | Ono Pharmaceutical Co., Ltd. | Medicinal composition for inhalation |
EP1841733A2 (en) | 2004-11-08 | 2007-10-10 | Allergan, Inc. | Substituted pyrrolidone compounds as prostaglandin ep4 agonists |
MX2007006777A (es) * | 2004-12-06 | 2007-08-06 | Avigen Inc | Ibudilast para tratar dolor neuropatico y sindromes asociados. |
US7635716B2 (en) | 2005-01-14 | 2009-12-22 | Allergan, Inc. | Substituted cyclopentanes or cyclopentanones as therapeutic agents |
NZ560691A (en) * | 2005-03-10 | 2011-03-31 | Allergan Inc | Substituted gamma lactams as therapeutic agents |
CA2610692C (en) * | 2005-06-03 | 2014-11-25 | Ono Pharmaceutical Co., Ltd. | Ep2 agonists which may have an ep3 agonistic effect for regeneration and/or protection of nerves |
WO2007005176A1 (en) * | 2005-06-29 | 2007-01-11 | Allergan, Inc. | Pyrrolidinones for the treatment of glaucoma and ocular hypertension |
US7893107B2 (en) | 2005-11-30 | 2011-02-22 | Allergan, Inc. | Therapeutic methods using prostaglandin EP4 agonist components |
US7323591B2 (en) | 2006-01-10 | 2008-01-29 | Allergan, Inc. | Substituted cyclopentanes or cyclopentanones as therapeutic agents |
US20070232660A1 (en) * | 2006-04-04 | 2007-10-04 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
US7557095B2 (en) * | 2006-05-12 | 2009-07-07 | Allergan, Inc. | Therapeutic compounds |
US7507833B2 (en) | 2006-08-10 | 2009-03-24 | Allergan, Inc. | Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives |
CN101522669B (zh) * | 2006-08-11 | 2013-01-16 | 阿勒根公司 | 治疗用内酰胺 |
US7795287B2 (en) | 2006-09-01 | 2010-09-14 | Allergan, Inc. | Therapeutic substituted hydantoins and related compounds |
EP2269611B1 (en) | 2006-11-16 | 2016-03-23 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza A viral infection |
KR20080055355A (ko) * | 2006-12-15 | 2008-06-19 | 에스케이케미칼주식회사 | 보관안정성이 우수한 클로피도그렐 함유 포접 복합체 |
AU2007334038A1 (en) * | 2006-12-18 | 2008-06-26 | Allergan, Inc. | Methods and compositions for treating gastrointestinal disorders |
EP2131841B1 (en) * | 2007-01-30 | 2012-08-01 | Avigen, Inc. | Methods for treating acute pain |
WO2008094912A2 (en) * | 2007-01-31 | 2008-08-07 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
CN101657445B (zh) * | 2007-02-15 | 2013-06-05 | 阿勒根公司 | 治疗青光眼或眼内压升高的γ内酰胺 |
EP2123273B1 (en) | 2007-02-16 | 2013-10-23 | ONO Pharmaceutical Co., Ltd. | Therapeutic agent for urinary excretion disorder |
US7589213B2 (en) * | 2007-04-27 | 2009-09-15 | Old David W | Therapeutic substituted lactams |
WO2008137012A1 (en) * | 2007-05-03 | 2008-11-13 | Avigen, Inc. | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
WO2008136519A1 (ja) * | 2007-05-08 | 2008-11-13 | National University Corporation, Hamamatsu University School Of Medicine | Ep4アゴニストを含有してなる細胞傷害性t細胞の活性化剤 |
LT2264009T (lt) | 2008-03-12 | 2019-04-25 | Ube Industries, Ltd. | Piridilaminoacto rūgšties junginys |
US7956055B2 (en) | 2008-03-25 | 2011-06-07 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
JP5524181B2 (ja) * | 2008-04-24 | 2014-06-18 | アラーガン インコーポレイテッド | 治療剤としての置換ガンマラクタム |
WO2009140205A2 (en) | 2008-05-15 | 2009-11-19 | Allergan, Inc. | Therapeutic substituted cyclopentanes |
EP2149552A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors |
EP2149554A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolylamide als Modulatoren des EP2-Rezeptors |
EP2149551A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors |
CN102209719B (zh) | 2008-09-10 | 2014-05-14 | 旭硝子株式会社 | 新型前列腺素i2衍生物 |
JP5300033B2 (ja) | 2009-03-30 | 2013-09-25 | 宇部興産株式会社 | 緑内障の治療又は予防のための医薬組成物 |
PT2441760E (pt) | 2009-06-10 | 2014-01-07 | Ono Pharmaceutical Co | Composto com actividade de contracção muscular do detrusor e actividade de relaxação muscular do esfíncter uretral |
GB2474120B (en) * | 2009-10-01 | 2011-12-21 | Amira Pharmaceuticals Inc | Compounds as Lysophosphatidic acid receptor antagonists |
GB2474748B (en) * | 2009-10-01 | 2011-10-12 | Amira Pharmaceuticals Inc | Polycyclic compounds as lysophosphatidic acid receptor antagonists |
TWI555744B (zh) | 2010-03-08 | 2016-11-01 | Kaken Pharma Co Ltd | Novel EP4 agonists |
JP2014513077A (ja) | 2011-04-05 | 2014-05-29 | アミラ ファーマシューティカルス,インコーポレーテッド | 線維症、疼痛、癌、ならびに呼吸器、アレルギー性、神経系または心血管疾患の治療に有用な3−または5−ビフェニル−4−イルイソキサゾールに基づく化合物 |
TW201326154A (zh) | 2011-11-28 | 2013-07-01 | 拜耳知識產權公司 | 作為ep2受體拮抗劑之新穎2h-吲唑 |
EP2874620B1 (en) | 2012-07-19 | 2016-10-12 | Cayman Chemical Company, Incorporated | Difluorolactam compositions for ep4-mediated osteo related diseases and conditions |
CA2882732C (en) | 2012-08-31 | 2021-03-30 | Ono Pharmaceutical Co., Ltd. | A 2-[(2-{(1r,5r)-2-oxo-5-[(1e,4s)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadiene-1-yl]cyclopentyl}ethyl)thio}-1,3-thiazole-4-carboxylic acid 4-piperidinemethanol salt and crystals thereof |
DK2989098T3 (en) | 2013-03-15 | 2017-08-28 | Cayman Chemical Co Inc | LACTAM RELATIONS AS EP4 RECEPTOR SELECTIVE AGONISTS FOR USING THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS |
WO2014144610A1 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
AU2014244926A1 (en) | 2013-03-28 | 2015-11-12 | Ube Industries, Ltd. | Substituted biaryl compound |
WO2015009991A2 (en) | 2013-07-19 | 2015-01-22 | Cayman Chemical Company, Inc. | Methods, systems, and compositions for promoting bone growth |
US9540357B1 (en) | 2014-07-31 | 2017-01-10 | Allergan, Inc. | 15-aryl prostaglandins as EP4 agonists, and methods of use thereof |
KR102376248B1 (ko) * | 2015-01-09 | 2022-03-21 | 오노 야꾸힝 고교 가부시키가이샤 | 삼환성 스피로 화합물 |
WO2017173024A1 (en) * | 2016-03-30 | 2017-10-05 | AyuVis Research LLC | Novel compositions and therapeutic methods |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS511461A (en) | 1974-06-24 | 1976-01-08 | Tanabe Seiyaku Co | 88 azapurosutansanjudotainoseiho |
GB1529852A (en) | 1975-03-21 | 1978-10-25 | Labaz | 8-azaprostaglandins and process for the preparation thereof |
NL7604330A (nl) | 1975-04-28 | 1976-11-01 | Syntex Inc | Werkwijze voor de bereiding van 8-azaprostaan- zuurderivaten. |
DE2556326A1 (de) | 1975-12-13 | 1977-06-23 | Hoechst Ag | Neue pyrrolidone und verfahren zu ihrer herstellung |
IL49325A (en) | 1976-03-31 | 1979-11-30 | Labaz | 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them |
DE2619638A1 (de) | 1976-05-04 | 1977-11-17 | Hoechst Ag | Pyrrolidone und verfahren zu ihrer herstellung |
EP0471201A1 (de) | 1990-07-21 | 1992-02-19 | Hoechst Aktiengesellschaft | Neue Oxazolidinon-Derivate und ihre Verwendung als Dotierstoffe in Flüssigkristallmischungen |
US5280034A (en) * | 1991-08-23 | 1994-01-18 | E. R. Squibb & Sons, Inc. | Bis-heterocyclic prostaglandin analogs |
IT1254373B (it) | 1992-05-29 | 1995-09-14 | Eteroprostanoidi, procedimento per la loro preparazione e loro impiegoterapeutico. | |
US5362879A (en) * | 1993-04-15 | 1994-11-08 | Bristol-Myers Squibb Company | 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation |
TW401408B (en) * | 1995-07-21 | 2000-08-11 | Fujisawa Pharmaceutical Co | Heterocyclic compounds having prostaglandin I2 agonism |
CN1413190A (zh) | 1999-12-22 | 2003-04-23 | 辉瑞产品公司 | 治疗骨质疏松的ep4受体选择性激动剂 |
DK1132086T3 (da) | 2000-01-31 | 2006-08-28 | Pfizer Prod Inc | Anvendelse af prostaglandin (PGE2) selektive receptor 4 (EP4) agonister til behandling af akut og kronisk nyresvigt |
US20010056060A1 (en) | 2000-02-07 | 2001-12-27 | Cameron Kimberly O. | Treatment of osteoporsis with EP2/EP4 receptor selective agonists |
WO2002024647A1 (fr) | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
IL155368A0 (en) * | 2000-11-27 | 2003-11-23 | Pfizer Prod Inc | Ep4 receptor selective agonists in the treatment of osteoporosis |
ES2254726T3 (es) * | 2001-07-16 | 2006-06-16 | F. Hoffmann-La Roche Ag | Analogos de prostaglandina como agonistas receptores de ep4. |
EP1408961B1 (en) | 2001-07-16 | 2007-07-11 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
HU230421B1 (hu) * | 2001-07-23 | 2016-05-30 | Ono Pharmaceutical Co., Ltd | Csonttömegveszteséggel kapcsolatos betegségek kezelésére adható, EP4 agonistát tartalmazó gyógyászati készítmények és hatóanyagként alkalmazható vegyületek |
US20040204590A1 (en) * | 2001-12-03 | 2004-10-14 | Ogidigben Miller J. | Ep4 receptor agonist, compositions and methods thereof |
EP1461026A2 (en) * | 2001-12-03 | 2004-09-29 | Merck & Co., Inc. | Method for treating ocular hypertension |
US7858650B2 (en) * | 2004-10-22 | 2010-12-28 | Ono Pharmaceutical Co., Ltd. | Medicinal composition for inhalation |
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2003
- 2003-03-04 EP EP03743585A patent/EP1481976B1/en not_active Expired - Lifetime
- 2003-03-04 BR BR0308166-4A patent/BR0308166A/pt not_active IP Right Cessation
- 2003-03-04 KR KR1020047013858A patent/KR100704215B1/ko not_active IP Right Cessation
- 2003-03-04 JP JP2003572953A patent/JP4547912B2/ja not_active Expired - Fee Related
- 2003-03-04 US US10/506,536 patent/US7402605B2/en not_active Expired - Fee Related
- 2003-03-04 RU RU2004129584/04A patent/RU2306309C2/ru not_active IP Right Cessation
- 2003-03-04 AU AU2003211574A patent/AU2003211574A1/en not_active Abandoned
- 2003-03-04 CA CA002477715A patent/CA2477715A1/en not_active Abandoned
- 2003-03-04 TW TW092104500A patent/TW200305425A/zh unknown
- 2003-03-04 WO PCT/JP2003/002478 patent/WO2003074483A1/ja active Application Filing
- 2003-03-04 NZ NZ535024A patent/NZ535024A/en unknown
- 2003-03-04 PL PL03372084A patent/PL372084A1/pl not_active Application Discontinuation
- 2003-03-04 IL IL16386603A patent/IL163866A0/xx unknown
- 2003-03-04 CN CNA03810251XA patent/CN1653046A/zh active Pending
- 2003-03-04 MX MXPA04008596A patent/MXPA04008596A/es not_active Application Discontinuation
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- 2008-06-13 US US12/139,260 patent/US7683094B2/en not_active Expired - Fee Related
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- 2009-11-17 JP JP2009262122A patent/JP2010077142A/ja not_active Withdrawn
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MXPA04008596A (es) | 2004-12-06 |
NZ535024A (en) | 2006-10-27 |
TW200305425A (en) | 2003-11-01 |
KR20040095264A (ko) | 2004-11-12 |
EP1481976A4 (en) | 2006-01-18 |
JP2010077142A (ja) | 2010-04-08 |
RU2306309C2 (ru) | 2007-09-20 |
IL163866A0 (en) | 2005-12-18 |
CN1653046A (zh) | 2005-08-10 |
AU2003211574A1 (en) | 2003-09-16 |
EP1481976A1 (en) | 2004-12-01 |
JPWO2003074483A1 (ja) | 2005-06-30 |
BR0308166A (pt) | 2005-01-18 |
US20050124577A1 (en) | 2005-06-09 |
WO2003074483A1 (fr) | 2003-09-12 |
KR100704215B1 (ko) | 2007-04-10 |
RU2004129584A (ru) | 2005-05-27 |
CA2477715A1 (en) | 2003-09-12 |
NO20043702L (no) | 2004-12-03 |
US20090042885A1 (en) | 2009-02-12 |
US8026273B2 (en) | 2011-09-27 |
US7683094B2 (en) | 2010-03-23 |
JP4547912B2 (ja) | 2010-09-22 |
EP1481976B1 (en) | 2012-11-07 |
US7402605B2 (en) | 2008-07-22 |
US20100113388A1 (en) | 2010-05-06 |
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