BR112015024743A2 - composto de biarila substituída - Google Patents
composto de biarila substituídaInfo
- Publication number
- BR112015024743A2 BR112015024743A2 BR112015024743A BR112015024743A BR112015024743A2 BR 112015024743 A2 BR112015024743 A2 BR 112015024743A2 BR 112015024743 A BR112015024743 A BR 112015024743A BR 112015024743 A BR112015024743 A BR 112015024743A BR 112015024743 A2 BR112015024743 A2 BR 112015024743A2
- Authority
- BR
- Brazil
- Prior art keywords
- substituted biaryl
- biaryl compound
- compound
- present
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Abstract
resumo patente de invenção para: "composto de biarila substituída." a presente invenção fornece um composto de biarila substituída de fórmula geral (i) (em que, r1, w, r2, e z são como definidos nas reivindicações e descrição), ou um sal farmacologicamente aceitável do mesmo. o composto de acordo com a presente invenção tem um efeito de inibição excelente de proliferação de um fibroblasto pulmonar, e é, portanto, útil como um agente terapêutico e/ou um agente profilático para pneumonia intersticial e fibrose pulmonar.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013069363 | 2013-03-28 | ||
JP2013228489 | 2013-11-01 | ||
PCT/JP2014/059301 WO2014157672A1 (ja) | 2013-03-28 | 2014-03-28 | 置換ビアリール化合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015024743A2 true BR112015024743A2 (pt) | 2017-07-18 |
Family
ID=51624629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015024743A BR112015024743A2 (pt) | 2013-03-28 | 2014-03-28 | composto de biarila substituída |
Country Status (15)
Country | Link |
---|---|
US (1) | US9676720B2 (pt) |
EP (1) | EP2980075A4 (pt) |
JP (1) | JPWO2014157672A1 (pt) |
KR (1) | KR20150135460A (pt) |
CN (1) | CN105308023A (pt) |
AU (1) | AU2014244926A1 (pt) |
BR (1) | BR112015024743A2 (pt) |
CA (1) | CA2908223A1 (pt) |
HK (2) | HK1219103A1 (pt) |
MX (1) | MX2015013848A (pt) |
PH (1) | PH12015502255A1 (pt) |
RU (1) | RU2015145989A (pt) |
SG (1) | SG11201507976YA (pt) |
TW (1) | TW201527282A (pt) |
WO (1) | WO2014157672A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10519112B2 (en) | 2014-06-10 | 2019-12-31 | Ube Industries, Ltd. | Method for producing heteroaromatic sulfonamide compound |
CA2951784C (en) * | 2014-06-10 | 2022-05-31 | Ube Industries, Ltd. | N-substituted sulfonamide compound and method for producing same |
US10774072B2 (en) | 2014-06-10 | 2020-09-15 | Ube Industries, Ltd. | Crystal of N-substituted sulfonamide compound |
JP2017206445A (ja) * | 2014-09-26 | 2017-11-24 | 宇部興産株式会社 | 呼吸器疾患の治療及び/又は予防のための医薬組成物 |
JP2017206443A (ja) * | 2014-09-26 | 2017-11-24 | 宇部興産株式会社 | 置換ビアリール化合物及び他の医薬の組み合わせ |
CN108884047B (zh) * | 2016-03-25 | 2022-03-08 | 沈阳三生制药有限责任公司 | 用于合成被芳基或杂芳基取代的5-羟基-1,7-萘啶化合物的中间体及其制备方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA59384C2 (uk) | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
UA67754C2 (uk) | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
US20020063763A1 (en) | 2000-11-29 | 2002-05-30 | Mantell David Allen | Apparatus and method for removing air bubbles from an ink jet printhead |
CA2401984A1 (en) | 2000-03-22 | 2001-09-27 | Merck Frosst Canada Inc. | Sulfur substituted aryldifluoromethylphosphonic acids as ptp-1b inhibitors |
AU2003211574A1 (en) | 2002-03-05 | 2003-09-16 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
WO2004078169A1 (en) | 2003-03-04 | 2004-09-16 | Pfizer Products Inc. | Use of ep2 selective receptor agonists in medical treatment |
EP1723132A1 (en) | 2004-02-12 | 2006-11-22 | Asterand Uk Limited | Ep2 receptor agonists |
WO2006043655A1 (ja) | 2004-10-22 | 2006-04-27 | Ono Pharmaceutical Co., Ltd. | 吸入用医薬組成物 |
CA2593439C (en) | 2005-01-14 | 2014-02-25 | F. Hoffmann-La Roche Ag | Thiazole-4-carboxamide derivatives as mglur5 antagonists |
CA2618486A1 (en) | 2005-08-09 | 2007-02-15 | Asterand Uk Limited | Ep2 receptor agonists |
JP4583500B2 (ja) | 2006-07-28 | 2010-11-17 | ファイザー・プロダクツ・インク | Ep2作動薬 |
CN101495452B (zh) * | 2006-07-28 | 2012-04-25 | 辉瑞产品公司 | Ep2激动剂 |
WO2008065500A2 (en) * | 2006-11-30 | 2008-06-05 | Pfizer Products Inc. | Heteroaryl amides as type i glycine transport inhibitors |
JP2010524858A (ja) | 2007-04-10 | 2010-07-22 | エスジーエックス ファーマシューティカルズ、インコーポレイテッド | 縮合環複素環キナーゼ調節因子 |
DK2264009T3 (en) * | 2008-03-12 | 2019-04-15 | Ube Industries | PYRIDYLAMINE ACEDIC ACID COMPOUND |
SI2415763T1 (sl) * | 2009-03-30 | 2016-05-31 | Ube Industries, Ltd. | Farmacevtski sestavek za zdravljenje ali preprečevanje glavkoma |
EP2476668B1 (en) | 2009-09-11 | 2013-11-06 | Ube Industries, Ltd. | Aniline compounds |
WO2011030873A1 (ja) | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | ベンジル化合物 |
WO2011030865A1 (ja) | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | 置換ベンジル化合物 |
EP2476678A4 (en) | 2009-09-11 | 2013-02-20 | Ube Industries | SUBSTITUTED CARBONYL COMPOUNDS |
WO2011030872A1 (ja) | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | スルホンアミド化合物 |
WO2011030871A1 (ja) | 2009-09-11 | 2011-03-17 | 宇部興産株式会社 | N-置換ヘテロアリール化合物 |
CA2785668A1 (en) | 2009-12-25 | 2011-06-30 | Ube Industries, Ltd. | Aminopyridine compound |
TW201542525A (zh) * | 2013-09-02 | 2015-11-16 | Ube Industries | 肺疾患的治療及/或預防用的醫藥組成物 |
-
2014
- 2014-03-28 CN CN201480018212.0A patent/CN105308023A/zh active Pending
- 2014-03-28 SG SG11201507976YA patent/SG11201507976YA/en unknown
- 2014-03-28 RU RU2015145989A patent/RU2015145989A/ru not_active Application Discontinuation
- 2014-03-28 MX MX2015013848A patent/MX2015013848A/es unknown
- 2014-03-28 AU AU2014244926A patent/AU2014244926A1/en not_active Abandoned
- 2014-03-28 JP JP2015508791A patent/JPWO2014157672A1/ja not_active Ceased
- 2014-03-28 EP EP14775434.5A patent/EP2980075A4/en not_active Withdrawn
- 2014-03-28 US US14/780,249 patent/US9676720B2/en not_active Expired - Fee Related
- 2014-03-28 KR KR1020157030613A patent/KR20150135460A/ko not_active Application Discontinuation
- 2014-03-28 CA CA2908223A patent/CA2908223A1/en not_active Abandoned
- 2014-03-28 WO PCT/JP2014/059301 patent/WO2014157672A1/ja active Application Filing
- 2014-03-28 BR BR112015024743A patent/BR112015024743A2/pt active Search and Examination
- 2014-03-28 TW TW103111881A patent/TW201527282A/zh unknown
-
2015
- 2015-09-28 PH PH12015502255A patent/PH12015502255A1/en unknown
-
2016
- 2016-06-21 HK HK16107171.8A patent/HK1219103A1/zh unknown
- 2016-07-18 HK HK16108507.1A patent/HK1220457A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HK1220457A1 (zh) | 2017-05-05 |
JPWO2014157672A1 (ja) | 2017-02-16 |
PH12015502255A1 (en) | 2016-02-01 |
CA2908223A1 (en) | 2014-10-02 |
SG11201507976YA (en) | 2015-10-29 |
WO2014157672A1 (ja) | 2014-10-02 |
CN105308023A (zh) | 2016-02-03 |
RU2015145989A (ru) | 2017-05-16 |
US20160060221A1 (en) | 2016-03-03 |
EP2980075A4 (en) | 2016-08-10 |
EP2980075A1 (en) | 2016-02-03 |
HK1219103A1 (zh) | 2017-03-24 |
MX2015013848A (es) | 2016-03-01 |
TW201527282A (zh) | 2015-07-16 |
AU2014244926A1 (en) | 2015-11-12 |
US9676720B2 (en) | 2017-06-13 |
KR20150135460A (ko) | 2015-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A ANUIDADE. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2507 DE 22-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
|
B07E | Notice of approval relating to section 229 industrial property law |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |