PL3597738T3 - Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu - Google Patents

Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu

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Publication number
PL3597738T3
PL3597738T3 PL19742120.9T PL19742120T PL3597738T3 PL 3597738 T3 PL3597738 T3 PL 3597738T3 PL 19742120 T PL19742120 T PL 19742120T PL 3597738 T3 PL3597738 T3 PL 3597738T3
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PL
Poland
Prior art keywords
homoserine
derived
amino acid
same
producing
Prior art date
Application number
PL19742120.9T
Other languages
English (en)
Inventor
Hyo Jin Kim
Lan HUH
Sang Jo Lim
Hyun Ah Kim
Hyung Joon Kim
Chang Il Seo
Seung Bin Lee
Ji Sun Lee
Original Assignee
Cj Cheiljedang Corporation
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Publication date
Application filed by Cj Cheiljedang Corporation filed Critical Cj Cheiljedang Corporation
Publication of PL3597738T3 publication Critical patent/PL3597738T3/pl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01003Homoserine dehydrogenase (1.1.1.3)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PL19742120.9T 2018-05-28 2019-05-21 Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu PL3597738T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180060445A KR101947959B1 (ko) 2018-05-28 2018-05-28 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
PCT/KR2019/006083 WO2019231159A1 (ko) 2018-05-28 2019-05-21 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법

Publications (1)

Publication Number Publication Date
PL3597738T3 true PL3597738T3 (pl) 2023-07-17

Family

ID=65366474

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19742120.9T PL3597738T3 (pl) 2018-05-28 2019-05-21 Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu

Country Status (20)

Country Link
US (2) US11236374B2 (pl)
EP (1) EP3597738B1 (pl)
JP (1) JP6938795B2 (pl)
KR (1) KR101947959B1 (pl)
CN (2) CN112143719B (pl)
AR (1) AR115415A1 (pl)
AU (1) AU2019279282B2 (pl)
BR (1) BR112019020697B1 (pl)
CA (1) CA3091741C (pl)
ES (1) ES2944588T3 (pl)
HU (1) HUE062601T2 (pl)
MX (1) MX2020007591A (pl)
PH (1) PH12020551031A1 (pl)
PL (1) PL3597738T3 (pl)
RU (1) RU2733426C1 (pl)
SA (1) SA520420007B1 (pl)
SG (1) SG11202006718YA (pl)
TW (1) TWI740150B (pl)
WO (1) WO2019231159A1 (pl)
ZA (1) ZA202004021B (pl)

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KR102175112B1 (ko) 2019-04-22 2020-11-06 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 강화된 미생물 및 이를 이용한 쓰레오닌 생산방법
KR102207867B1 (ko) 2020-01-21 2021-01-26 씨제이제일제당 주식회사 Nadp 의존적 글리세르알데하이드-3-포스페이트 디하이드로지나제를 포함하는 미생물을 이용하여 l-아미노산을 생산하는 방법
KR102363913B1 (ko) * 2020-06-26 2022-02-18 씨제이제일제당 (주) L-쓰레오닌 디하이드라타아제의 신규 변이체 및 이를 이용한 l-이소류신 생산 방법
KR102527895B1 (ko) 2021-01-11 2023-04-28 씨제이제일제당 (주) GlxR 단백질 변이체 또는 이를 이용한 쓰레오닌 생산방법
KR102273639B1 (ko) * 2021-04-20 2021-07-06 씨제이제일제당 주식회사 신규한 이중기능성 메틸렌테트라히드로폴레이트 탈수소효소/메테닐테트라하이드로폴레이트 사이클로하이드롤라아제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
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CN112143719A (zh) 2020-12-29
CN110945121B (zh) 2021-09-28
JP2021513341A (ja) 2021-05-27
SA520420007B1 (ar) 2024-02-29
EP3597738A4 (en) 2021-01-27
MX2020007591A (es) 2021-01-15
HUE062601T2 (hu) 2023-11-28
CN110945121A (zh) 2020-03-31
RU2733426C1 (ru) 2020-10-01
ZA202004021B (en) 2021-09-29
WO2019231159A1 (ko) 2019-12-05
PH12020551031A1 (en) 2021-08-16
US20210002682A1 (en) 2021-01-07
BR112019020697B1 (pt) 2022-04-26
KR101947959B1 (ko) 2019-02-13
JP6938795B2 (ja) 2021-09-22
AR115415A1 (es) 2021-01-13
SG11202006718YA (en) 2020-08-28
EP3597738B1 (en) 2023-04-05
ES2944588T3 (es) 2023-06-22
AU2019279282B2 (en) 2022-03-03
AU2019279282A1 (en) 2020-07-16
BR112019020697A2 (pt) 2021-02-17
CA3091741A1 (en) 2019-12-05
EP3597738A1 (en) 2020-01-22
TWI740150B (zh) 2021-09-21
US11236374B2 (en) 2022-02-01
US20210403962A1 (en) 2021-12-30
CN112143719B (zh) 2023-11-24
CA3091741C (en) 2023-10-31
US11555213B2 (en) 2023-01-17
TW202000914A (zh) 2020-01-01

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