PL354176A1 - Antagoniści receptora witronektynyAntagoniści receptora witronektyny - Google Patents
Antagoniści receptora witronektynyAntagoniści receptora witronektynyInfo
- Publication number
- PL354176A1 PL354176A1 PL00354176A PL35417600A PL354176A1 PL 354176 A1 PL354176 A1 PL 354176A1 PL 00354176 A PL00354176 A PL 00354176A PL 35417600 A PL35417600 A PL 35417600A PL 354176 A1 PL354176 A1 PL 354176A1
- Authority
- PL
- Poland
- Prior art keywords
- receptor antagonists
- vitronectin receptor
- vitronectin
- antagonists
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- External Artificial Organs (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15278099P | 1999-09-07 | 1999-09-07 | |
| PCT/US2000/024514 WO2001017959A2 (en) | 1999-09-07 | 2000-09-07 | Vitronectin receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL354176A1 true PL354176A1 (pl) | 2003-12-29 |
| PL200404B1 PL200404B1 (pl) | 2009-01-30 |
Family
ID=22544416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL354176A PL200404B1 (pl) | 1999-09-07 | 2000-09-07 | Antagoniści receptora witronektyny-arylopodstawione pochodne kwasu butanowego, zawierająca je kompozycja farmaceutyczna i ich zastosowania |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1218005B1 (pl) |
| JP (1) | JP4685307B2 (pl) |
| KR (1) | KR100711170B1 (pl) |
| CN (1) | CN1236767C (pl) |
| AR (1) | AR025589A1 (pl) |
| AT (1) | ATE284870T1 (pl) |
| AU (1) | AU768918B2 (pl) |
| BR (1) | BR0013749A (pl) |
| CA (1) | CA2384671A1 (pl) |
| CO (1) | CO5200845A1 (pl) |
| CZ (1) | CZ2002822A3 (pl) |
| DE (1) | DE60016769T2 (pl) |
| EG (1) | EG24179A (pl) |
| ES (1) | ES2234658T3 (pl) |
| GC (1) | GC0000203A (pl) |
| HK (1) | HK1049110B (pl) |
| HU (1) | HUP0202710A3 (pl) |
| IL (2) | IL148325A0 (pl) |
| MX (1) | MXPA02002455A (pl) |
| NO (1) | NO322109B1 (pl) |
| NZ (1) | NZ517296A (pl) |
| PE (1) | PE20010582A1 (pl) |
| PL (1) | PL200404B1 (pl) |
| PT (1) | PT1218005E (pl) |
| TR (1) | TR200200614T2 (pl) |
| TW (1) | TWI255813B (pl) |
| UY (1) | UY26329A1 (pl) |
| WO (1) | WO2001017959A2 (pl) |
| ZA (1) | ZA200201780B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6531494B1 (en) | 2001-08-29 | 2003-03-11 | Pharmacia Corporation | Gem-substituted αvβ3 antagonists |
| US6982263B2 (en) | 2001-06-08 | 2006-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitriles useful as reversible inhibitors of cysteine proteases |
| GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| AU2005219737B2 (en) * | 2004-03-05 | 2009-11-19 | Taisho Pharmaceutical Co., Ltd. | Thiazole derivative |
| CA2804744C (en) | 2010-07-14 | 2019-05-28 | Novartis Ag | Ip receptor agonist 1,8-naphthyridinyl and 7,8-dihydropyrido[3,2-b]pyrazinyl heterocyclic compounds |
| JP6073923B2 (ja) | 2012-01-13 | 2017-02-01 | ノバルティス アーゲー | 肺動脈高血圧症（ｐａｈ）および関連障害の治療のためのｉｐ受容体アゴニストとしての縮合ピロール |
| JP2016507582A (ja) | 2013-02-13 | 2016-03-10 | ノバルティス アーゲー | Ｉｐ受容体アゴニスト複素環式化合物 |
| CN108675954A (zh) * | 2018-04-03 | 2018-10-19 | 爱斯特（成都）生物制药股份有限公司 | 2-氨基-3-羟甲基吡啶的一种制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08325264A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−芳香環置換−３−フェニルプロピオン酸またはアクリル酸誘導体 |
| JPH08325263A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−アミノ−３−フェニルプロピオン酸誘導体 |
| JP2000502708A (ja) * | 1995-12-29 | 2000-03-07 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗物質 |
| AU8750298A (en) * | 1997-08-28 | 1999-03-22 | Ono Pharmaceutical Co. Ltd. | Peroxisome proliferator-activated receptor controllers |
| PE122699A1 (es) * | 1997-09-19 | 2000-02-12 | Smithkline Beecham Corp | Antagonistas de receptores de vitronectina |
| PE20000323A1 (es) * | 1998-03-10 | 2000-05-24 | Smithkline Beecham Corp | Antagonistas de receptor de vitronectina |
| WO2000009503A1 (en) * | 1998-08-13 | 2000-02-24 | Merck & Co., Inc. | Integrin receptor antagonists |
-
2000
- 2000-09-05 EG EG20001132A patent/EG24179A/xx active
- 2000-09-06 CO CO00067158A patent/CO5200845A1/es not_active Application Discontinuation
- 2000-09-06 PE PE2000000909A patent/PE20010582A1/es not_active Application Discontinuation
- 2000-09-06 UY UY26329A patent/UY26329A1/es not_active Application Discontinuation
- 2000-09-07 AT AT00961619T patent/ATE284870T1/de not_active IP Right Cessation
- 2000-09-07 MX MXPA02002455A patent/MXPA02002455A/es active IP Right Grant
- 2000-09-07 NZ NZ517296A patent/NZ517296A/en unknown
- 2000-09-07 PL PL354176A patent/PL200404B1/pl not_active IP Right Cessation
- 2000-09-07 TR TR2002/00614T patent/TR200200614T2/xx unknown
- 2000-09-07 BR BR0013749-9A patent/BR0013749A/pt not_active Application Discontinuation
- 2000-09-07 EP EP00961619A patent/EP1218005B1/en not_active Expired - Lifetime
- 2000-09-07 HU HU0202710A patent/HUP0202710A3/hu unknown
- 2000-09-07 AU AU73543/00A patent/AU768918B2/en not_active Ceased
- 2000-09-07 KR KR1020027002979A patent/KR100711170B1/ko not_active IP Right Cessation
- 2000-09-07 JP JP2001521706A patent/JP4685307B2/ja not_active Expired - Fee Related
- 2000-09-07 ES ES00961619T patent/ES2234658T3/es not_active Expired - Lifetime
- 2000-09-07 PT PT00961619T patent/PT1218005E/pt unknown
- 2000-09-07 CN CNB008126135A patent/CN1236767C/zh not_active Expired - Fee Related
- 2000-09-07 CA CA002384671A patent/CA2384671A1/en not_active Abandoned
- 2000-09-07 AR ARP000104681A patent/AR025589A1/es unknown
- 2000-09-07 WO PCT/US2000/024514 patent/WO2001017959A2/en active IP Right Grant
- 2000-09-07 CZ CZ2002822A patent/CZ2002822A3/cs unknown
- 2000-09-07 IL IL14832500A patent/IL148325A0/xx active IP Right Grant
- 2000-09-07 DE DE60016769T patent/DE60016769T2/de not_active Expired - Lifetime
- 2000-09-09 GC GCP2000894 patent/GC0000203A/en active
- 2000-09-25 TW TW089118280A patent/TWI255813B/zh not_active IP Right Cessation
-
2002
- 2002-02-21 IL IL148325A patent/IL148325A/en not_active IP Right Cessation
- 2002-03-04 ZA ZA200201780A patent/ZA200201780B/xx unknown
- 2002-03-06 NO NO20021113A patent/NO322109B1/no not_active IP Right Cessation
- 2002-12-23 HK HK02109309.5A patent/HK1049110B/zh not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Decisions on the lapse of the protection rights |
Effective date: 20090907 |