HUP0202710A3 - Vitronectin receptor antagonists, pharmaceutical compositions containing them and their use - Google Patents
Vitronectin receptor antagonists, pharmaceutical compositions containing them and their useInfo
- Publication number
- HUP0202710A3 HUP0202710A3 HU0202710A HUP0202710A HUP0202710A3 HU P0202710 A3 HUP0202710 A3 HU P0202710A3 HU 0202710 A HU0202710 A HU 0202710A HU P0202710 A HUP0202710 A HU P0202710A HU P0202710 A3 HUP0202710 A3 HU P0202710A3
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- receptor antagonists
- vitronectin receptor
- vitronectin
- Prior art date
Links
- 102100022337 Integrin alpha-V Human genes 0.000 title 1
- 108010048673 Vitronectin Receptors Proteins 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15278099P | 1999-09-07 | 1999-09-07 | |
| PCT/US2000/024514 WO2001017959A2 (en) | 1999-09-07 | 2000-09-07 | Vitronectin receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0202710A2 HUP0202710A2 (hu) | 2002-12-28 |
| HUP0202710A3 true HUP0202710A3 (en) | 2003-06-30 |
Family
ID=22544416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0202710A HUP0202710A3 (en) | 1999-09-07 | 2000-09-07 | Vitronectin receptor antagonists, pharmaceutical compositions containing them and their use |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1218005B1 (hu) |
| JP (1) | JP4685307B2 (hu) |
| KR (1) | KR100711170B1 (hu) |
| CN (1) | CN1236767C (hu) |
| AR (1) | AR025589A1 (hu) |
| AT (1) | ATE284870T1 (hu) |
| AU (1) | AU768918B2 (hu) |
| BR (1) | BR0013749A (hu) |
| CA (1) | CA2384671A1 (hu) |
| CO (1) | CO5200845A1 (hu) |
| CZ (1) | CZ2002822A3 (hu) |
| DE (1) | DE60016769T2 (hu) |
| EG (1) | EG24179A (hu) |
| ES (1) | ES2234658T3 (hu) |
| GC (1) | GC0000203A (hu) |
| HK (1) | HK1049110B (hu) |
| HU (1) | HUP0202710A3 (hu) |
| IL (2) | IL148325A0 (hu) |
| MX (1) | MXPA02002455A (hu) |
| NO (1) | NO322109B1 (hu) |
| NZ (1) | NZ517296A (hu) |
| PE (1) | PE20010582A1 (hu) |
| PL (1) | PL200404B1 (hu) |
| PT (1) | PT1218005E (hu) |
| TR (1) | TR200200614T2 (hu) |
| TW (1) | TWI255813B (hu) |
| UY (1) | UY26329A1 (hu) |
| WO (1) | WO2001017959A2 (hu) |
| ZA (1) | ZA200201780B (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6531494B1 (en) | 2001-08-29 | 2003-03-11 | Pharmacia Corporation | Gem-substituted αvβ3 antagonists |
| US6982263B2 (en) | 2001-06-08 | 2006-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitriles useful as reversible inhibitors of cysteine proteases |
| GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| RU2367661C2 (ru) * | 2004-03-05 | 2009-09-20 | Тайсо Фармасьютикал Ко., Лтд. | Производные тиазола |
| ES2622519T3 (es) | 2010-07-14 | 2017-07-06 | Novartis Ag | Componentes heterocíclicos agonistas del receptor IP |
| AR089698A1 (es) | 2012-01-13 | 2014-09-10 | Novartis Ag | Compuestos heterociclicos antagonistas del receptor ip |
| US9604981B2 (en) | 2013-02-13 | 2017-03-28 | Novartis Ag | IP receptor agonist heterocyclic compounds |
| CN108675954A (zh) * | 2018-04-03 | 2018-10-19 | 爱斯特（成都）生物制药股份有限公司 | 2-氨基-3-羟甲基吡啶的一种制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08325263A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−アミノ−３−フェニルプロピオン酸誘導体 |
| JPH08325264A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−芳香環置換−３−フェニルプロピオン酸またはアクリル酸誘導体 |
| JP2000502708A (ja) * | 1995-12-29 | 2000-03-07 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗物質 |
| WO1999011255A1 (en) * | 1997-08-28 | 1999-03-11 | Ono Pharmaceutical Co., Ltd. | Peroxisome proliferator-activated receptor controllers |
| DZ2609A1 (fr) * | 1997-09-19 | 2003-03-01 | Smithkline Beecham Corp | Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant. |
| BR9908636A (pt) * | 1998-03-10 | 2002-01-08 | Smithkline Beecham Corp | Antagonistas de receptor vitronectina |
| AU748621B2 (en) * | 1998-08-13 | 2002-06-06 | Merck & Co., Inc. | Integrin receptor antagonists |
-
2000
- 2000-09-05 EG EG20001132A patent/EG24179A/xx active
- 2000-09-06 CO CO00067158A patent/CO5200845A1/es not_active Application Discontinuation
- 2000-09-06 PE PE2000000909A patent/PE20010582A1/es not_active Application Discontinuation
- 2000-09-06 UY UY26329A patent/UY26329A1/es not_active Application Discontinuation
- 2000-09-07 PT PT00961619T patent/PT1218005E/pt unknown
- 2000-09-07 DE DE60016769T patent/DE60016769T2/de not_active Expired - Lifetime
- 2000-09-07 HK HK02109309.5A patent/HK1049110B/en not_active IP Right Cessation
- 2000-09-07 BR BR0013749-9A patent/BR0013749A/pt not_active Application Discontinuation
- 2000-09-07 EP EP00961619A patent/EP1218005B1/en not_active Expired - Lifetime
- 2000-09-07 HU HU0202710A patent/HUP0202710A3/hu unknown
- 2000-09-07 AT AT00961619T patent/ATE284870T1/de not_active IP Right Cessation
- 2000-09-07 IL IL14832500A patent/IL148325A0/xx active IP Right Grant
- 2000-09-07 CN CNB008126135A patent/CN1236767C/zh not_active Expired - Fee Related
- 2000-09-07 MX MXPA02002455A patent/MXPA02002455A/es active IP Right Grant
- 2000-09-07 KR KR1020027002979A patent/KR100711170B1/ko not_active Expired - Fee Related
- 2000-09-07 WO PCT/US2000/024514 patent/WO2001017959A2/en not_active Ceased
- 2000-09-07 PL PL354176A patent/PL200404B1/pl not_active IP Right Cessation
- 2000-09-07 CZ CZ2002822A patent/CZ2002822A3/cs unknown
- 2000-09-07 JP JP2001521706A patent/JP4685307B2/ja not_active Expired - Fee Related
- 2000-09-07 TR TR2002/00614T patent/TR200200614T2/xx unknown
- 2000-09-07 CA CA002384671A patent/CA2384671A1/en not_active Abandoned
- 2000-09-07 AU AU73543/00A patent/AU768918B2/en not_active Ceased
- 2000-09-07 AR ARP000104681A patent/AR025589A1/es unknown
- 2000-09-07 NZ NZ517296A patent/NZ517296A/en unknown
- 2000-09-07 ES ES00961619T patent/ES2234658T3/es not_active Expired - Lifetime
- 2000-09-09 GC GCP2000894 patent/GC0000203A/en active
- 2000-09-25 TW TW089118280A patent/TWI255813B/zh not_active IP Right Cessation
-
2002
- 2002-02-21 IL IL148325A patent/IL148325A/en not_active IP Right Cessation
- 2002-03-04 ZA ZA200201780A patent/ZA200201780B/xx unknown
- 2002-03-06 NO NO20021113A patent/NO322109B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |