NO20021113D0 - Vitronectin-reseptor-antagonister - Google Patents

Vitronectin-reseptor-antagonister

Info

Publication number
NO20021113D0
NO20021113D0 NO20021113A NO20021113A NO20021113D0 NO 20021113 D0 NO20021113 D0 NO 20021113D0 NO 20021113 A NO20021113 A NO 20021113A NO 20021113 A NO20021113 A NO 20021113A NO 20021113 D0 NO20021113 D0 NO 20021113D0
Authority
NO
Norway
Prior art keywords
receptor antagonists
vitronectin receptor
vitronectin
antagonists
receptor
Prior art date
Application number
NO20021113A
Other languages
English (en)
Other versions
NO322109B1 (no
NO20021113L (no
Inventor
Peter J Manley
William H Miller
Irene Nijole Uzinskas
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20021113D0 publication Critical patent/NO20021113D0/no
Publication of NO20021113L publication Critical patent/NO20021113L/no
Publication of NO322109B1 publication Critical patent/NO322109B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20021113A 1999-09-07 2002-03-06 Vitronektinreseporantagonister NO322109B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15278099P 1999-09-07 1999-09-07
PCT/US2000/024514 WO2001017959A2 (en) 1999-09-07 2000-09-07 Vitronectin receptor antagonists

Publications (3)

Publication Number Publication Date
NO20021113D0 true NO20021113D0 (no) 2002-03-06
NO20021113L NO20021113L (no) 2002-05-03
NO322109B1 NO322109B1 (no) 2006-08-14

Family

ID=22544416

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021113A NO322109B1 (no) 1999-09-07 2002-03-06 Vitronektinreseporantagonister

Country Status (29)

Country Link
EP (1) EP1218005B1 (no)
JP (1) JP4685307B2 (no)
KR (1) KR100711170B1 (no)
CN (1) CN1236767C (no)
AR (1) AR025589A1 (no)
AT (1) ATE284870T1 (no)
AU (1) AU768918B2 (no)
BR (1) BR0013749A (no)
CA (1) CA2384671A1 (no)
CO (1) CO5200845A1 (no)
CZ (1) CZ2002822A3 (no)
DE (1) DE60016769T2 (no)
EG (1) EG24179A (no)
ES (1) ES2234658T3 (no)
GC (1) GC0000203A (no)
HK (1) HK1049110B (no)
HU (1) HUP0202710A3 (no)
IL (2) IL148325A0 (no)
MX (1) MXPA02002455A (no)
NO (1) NO322109B1 (no)
NZ (1) NZ517296A (no)
PE (1) PE20010582A1 (no)
PL (1) PL200404B1 (no)
PT (1) PT1218005E (no)
TR (1) TR200200614T2 (no)
TW (1) TWI255813B (no)
UY (1) UY26329A1 (no)
WO (1) WO2001017959A2 (no)
ZA (1) ZA200201780B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531494B1 (en) 2001-08-29 2003-03-11 Pharmacia Corporation Gem-substituted αvβ3 antagonists
US6982263B2 (en) 2001-06-08 2006-01-03 Boehringer Ingelheim Pharmaceuticals, Inc. Nitriles useful as reversible inhibitors of cysteine proteases
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
EP1721905A4 (en) * 2004-03-05 2009-11-18 Taisho Pharmaceutical Co Ltd THIAZOLE DERIVATIVE
CN103097385B (zh) 2010-07-14 2016-08-03 诺华股份有限公司 Ip受体激动剂杂环化合物
TW201335160A (zh) 2012-01-13 2013-09-01 Novartis Ag Ip受體激動劑之雜環化合物
CN105189500A (zh) 2013-02-13 2015-12-23 诺华股份有限公司 Ip受体激动剂杂环化合物
CN108675954A (zh) * 2018-04-03 2018-10-19 爱斯特(成都)生物制药股份有限公司 2-氨基-3-羟甲基吡啶的一种制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08325264A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規2−芳香環置換−3−フェニルプロピオン酸またはアクリル酸誘導体
JPH08325263A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規2−アミノ−3−フェニルプロピオン酸誘導体
JP2000502708A (ja) * 1995-12-29 2000-03-07 スミスクライン・ビーチャム・コーポレイション ビトロネクチン受容体拮抗物質
AU8750298A (en) * 1997-08-28 1999-03-22 Ono Pharmaceutical Co. Ltd. Peroxisome proliferator-activated receptor controllers
AR015446A1 (es) * 1997-09-19 2001-05-02 Smithkline Beecham Corp Antagonistas de receptores de vitronectina, composicion farmaceutica que los contiene, procedimiento para su preparacion, su uso para la elaboracion de unmedicamento y compuestos intermediarios
UY25421A1 (es) * 1998-03-10 2001-07-31 Smithkline Beecham Corp Antagonistas de receptor de vitronectina
WO2000009503A1 (en) * 1998-08-13 2000-02-24 Merck & Co., Inc. Integrin receptor antagonists

Also Published As

Publication number Publication date
AU768918B2 (en) 2004-01-08
UY26329A1 (es) 2001-07-31
EP1218005A4 (en) 2002-10-09
CN1236767C (zh) 2006-01-18
JP4685307B2 (ja) 2011-05-18
WO2001017959A3 (en) 2001-05-10
IL148325A0 (en) 2002-09-12
KR100711170B1 (ko) 2007-04-27
EG24179A (en) 2008-09-28
TR200200614T2 (tr) 2002-07-22
DE60016769T2 (de) 2005-11-24
ES2234658T3 (es) 2005-07-01
GC0000203A (en) 2006-03-29
EP1218005B1 (en) 2004-12-15
CN1377269A (zh) 2002-10-30
MXPA02002455A (es) 2002-07-02
PE20010582A1 (es) 2001-06-23
CO5200845A1 (es) 2002-09-27
HK1049110A1 (en) 2003-05-02
NO322109B1 (no) 2006-08-14
ATE284870T1 (de) 2005-01-15
WO2001017959A2 (en) 2001-03-15
KR20020027624A (ko) 2002-04-13
AR025589A1 (es) 2002-12-04
CZ2002822A3 (cs) 2002-07-17
JP2003508516A (ja) 2003-03-04
BR0013749A (pt) 2003-06-10
IL148325A (en) 2007-06-03
NO20021113L (no) 2002-05-03
HK1049110B (zh) 2005-07-22
DE60016769D1 (de) 2005-01-20
PL354176A1 (en) 2003-12-29
PL200404B1 (pl) 2009-01-30
EP1218005A2 (en) 2002-07-03
AU7354300A (en) 2001-04-10
TWI255813B (en) 2006-06-01
ZA200201780B (en) 2003-05-28
NZ517296A (en) 2003-11-28
HUP0202710A2 (hu) 2002-12-28
PT1218005E (pt) 2005-05-31
HUP0202710A3 (en) 2003-06-30
CA2384671A1 (en) 2001-03-15

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