PT1218005E - Antagonistas do receptor de vitronectina - Google Patents
Antagonistas do receptor de vitronectinaInfo
- Publication number
- PT1218005E PT1218005E PT00961619T PT00961619T PT1218005E PT 1218005 E PT1218005 E PT 1218005E PT 00961619 T PT00961619 T PT 00961619T PT 00961619 T PT00961619 T PT 00961619T PT 1218005 E PT1218005 E PT 1218005E
- Authority
- PT
- Portugal
- Prior art keywords
- receptor antagonists
- vitronectin receptor
- vitronectin
- antagonists
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- External Artificial Organs (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15278099P | 1999-09-07 | 1999-09-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1218005E true PT1218005E (pt) | 2005-05-31 |
Family
ID=22544416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00961619T PT1218005E (pt) | 1999-09-07 | 2000-09-07 | Antagonistas do receptor de vitronectina |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1218005B1 (pt) |
| JP (1) | JP4685307B2 (pt) |
| KR (1) | KR100711170B1 (pt) |
| CN (1) | CN1236767C (pt) |
| AR (1) | AR025589A1 (pt) |
| AT (1) | ATE284870T1 (pt) |
| AU (1) | AU768918B2 (pt) |
| BR (1) | BR0013749A (pt) |
| CA (1) | CA2384671A1 (pt) |
| CO (1) | CO5200845A1 (pt) |
| CZ (1) | CZ2002822A3 (pt) |
| DE (1) | DE60016769T2 (pt) |
| EG (1) | EG24179A (pt) |
| ES (1) | ES2234658T3 (pt) |
| GC (1) | GC0000203A (pt) |
| HK (1) | HK1049110B (pt) |
| HU (1) | HUP0202710A3 (pt) |
| IL (2) | IL148325A0 (pt) |
| MX (1) | MXPA02002455A (pt) |
| NO (1) | NO322109B1 (pt) |
| NZ (1) | NZ517296A (pt) |
| PE (1) | PE20010582A1 (pt) |
| PL (1) | PL200404B1 (pt) |
| PT (1) | PT1218005E (pt) |
| TR (1) | TR200200614T2 (pt) |
| TW (1) | TWI255813B (pt) |
| UY (1) | UY26329A1 (pt) |
| WO (1) | WO2001017959A2 (pt) |
| ZA (1) | ZA200201780B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6531494B1 (en) | 2001-08-29 | 2003-03-11 | Pharmacia Corporation | Gem-substituted αvβ3 antagonists |
| US6982263B2 (en) | 2001-06-08 | 2006-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitriles useful as reversible inhibitors of cysteine proteases |
| GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| US7678810B2 (en) * | 2004-03-05 | 2010-03-16 | Taisho Pharmaceutical Co., Ltd | Thiazole derivative |
| CN103097385B (zh) | 2010-07-14 | 2016-08-03 | 诺华股份有限公司 | Ip受体激动剂杂环化合物 |
| TW201335160A (zh) | 2012-01-13 | 2013-09-01 | Novartis Ag | Ｉｐ受體激動劑之雜環化合物 |
| WO2014125413A1 (en) | 2013-02-13 | 2014-08-21 | Novartis Ag | Ip receptor agonist heterocyclic compounds |
| CN108675954A (zh) * | 2018-04-03 | 2018-10-19 | 爱斯特（成都）生物制药股份有限公司 | 2-氨基-3-羟甲基吡啶的一种制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08325263A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−アミノ−３−フェニルプロピオン酸誘導体 |
| JPH08325264A (ja) * | 1995-05-31 | 1996-12-10 | Sumitomo Metal Ind Ltd | 新規２−芳香環置換−３−フェニルプロピオン酸またはアクリル酸誘導体 |
| KR19990076876A (ko) * | 1995-12-29 | 1999-10-25 | 스티븐 베네티아너 | 비트로넥틴 수용체 길항제 |
| WO1999011255A1 (fr) * | 1997-08-28 | 1999-03-11 | Ono Pharmaceutical Co., Ltd. | Regulateurs du recepteur active par les agents de proliferation des peroxysomes |
| DZ2609A1 (fr) * | 1997-09-19 | 2003-03-01 | Smithkline Beecham Corp | Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant. |
| KR20010041812A (ko) * | 1998-03-10 | 2001-05-25 | 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 | 비트로넥틴 수용체 길항제 |
| CA2338878A1 (en) * | 1998-08-13 | 2000-02-24 | Merck & Co., Inc. | Integrin receptor antagonists |
-
2000
- 2000-09-05 EG EG20001132A patent/EG24179A/xx active
- 2000-09-06 UY UY26329A patent/UY26329A1/es not_active Application Discontinuation
- 2000-09-06 PE PE2000000909A patent/PE20010582A1/es not_active Application Discontinuation
- 2000-09-06 CO CO00067158A patent/CO5200845A1/es not_active Application Discontinuation
- 2000-09-07 KR KR1020027002979A patent/KR100711170B1/ko not_active IP Right Cessation
- 2000-09-07 WO PCT/US2000/024514 patent/WO2001017959A2/en active IP Right Grant
- 2000-09-07 EP EP00961619A patent/EP1218005B1/en not_active Expired - Lifetime
- 2000-09-07 AU AU73543/00A patent/AU768918B2/en not_active Ceased
- 2000-09-07 AR ARP000104681A patent/AR025589A1/es unknown
- 2000-09-07 BR BR0013749-9A patent/BR0013749A/pt not_active Application Discontinuation
- 2000-09-07 CZ CZ2002822A patent/CZ2002822A3/cs unknown
- 2000-09-07 DE DE60016769T patent/DE60016769T2/de not_active Expired - Lifetime
- 2000-09-07 CN CNB008126135A patent/CN1236767C/zh not_active Expired - Fee Related
- 2000-09-07 HU HU0202710A patent/HUP0202710A3/hu unknown
- 2000-09-07 JP JP2001521706A patent/JP4685307B2/ja not_active Expired - Fee Related
- 2000-09-07 MX MXPA02002455A patent/MXPA02002455A/es active IP Right Grant
- 2000-09-07 TR TR2002/00614T patent/TR200200614T2/xx unknown
- 2000-09-07 ES ES00961619T patent/ES2234658T3/es not_active Expired - Lifetime
- 2000-09-07 NZ NZ517296A patent/NZ517296A/en unknown
- 2000-09-07 CA CA002384671A patent/CA2384671A1/en not_active Abandoned
- 2000-09-07 IL IL14832500A patent/IL148325A0/xx active IP Right Grant
- 2000-09-07 PL PL354176A patent/PL200404B1/pl not_active IP Right Cessation
- 2000-09-07 PT PT00961619T patent/PT1218005E/pt unknown
- 2000-09-07 AT AT00961619T patent/ATE284870T1/de not_active IP Right Cessation
- 2000-09-09 GC GCP2000894 patent/GC0000203A/en active
- 2000-09-25 TW TW089118280A patent/TWI255813B/zh not_active IP Right Cessation
-
2002
- 2002-02-21 IL IL148325A patent/IL148325A/en not_active IP Right Cessation
- 2002-03-04 ZA ZA200201780A patent/ZA200201780B/xx unknown
- 2002-03-06 NO NO20021113A patent/NO322109B1/no not_active IP Right Cessation
- 2002-12-23 HK HK02109309.5A patent/HK1049110B/zh not_active IP Right Cessation
Also Published As
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