PL3307271T3 - Sposoby stosowania aktywatorów kinazy pirogronianowej - Google Patents

Sposoby stosowania aktywatorów kinazy pirogronianowej

Info

Publication number
PL3307271T3
PL3307271T3 PL16808374.9T PL16808374T PL3307271T3 PL 3307271 T3 PL3307271 T3 PL 3307271T3 PL 16808374 T PL16808374 T PL 16808374T PL 3307271 T3 PL3307271 T3 PL 3307271T3
Authority
PL
Poland
Prior art keywords
methods
pyruvate kinase
kinase activators
activators
pyruvate
Prior art date
Application number
PL16808374.9T
Other languages
English (en)
Inventor
Samuel V. Agresta
Yue Chen
Marvin Barry Cohen
Leonard Luan C. Dang
Charles KUNG
Elizabeth A. Merica
Bruce Alan Silver
Hua Yang
Original Assignee
Agios Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57504271&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3307271(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agios Pharmaceuticals, Inc. filed Critical Agios Pharmaceuticals, Inc.
Publication of PL3307271T3 publication Critical patent/PL3307271T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
PL16808374.9T 2015-06-11 2016-06-10 Sposoby stosowania aktywatorów kinazy pirogronianowej PL3307271T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562174216P 2015-06-11 2015-06-11
PCT/US2016/036893 WO2016201227A1 (en) 2015-06-11 2016-06-10 Methods of using pyruvate kinase activators

Publications (1)

Publication Number Publication Date
PL3307271T3 true PL3307271T3 (pl) 2024-02-05

Family

ID=57504271

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16808374.9T PL3307271T3 (pl) 2015-06-11 2016-06-10 Sposoby stosowania aktywatorów kinazy pirogronianowej

Country Status (20)

Country Link
US (3) US11234976B2 (pl)
EP (2) EP4344703A1 (pl)
JP (3) JP7320339B2 (pl)
AU (2) AU2016276951B2 (pl)
CA (1) CA2989111C (pl)
DK (1) DK3307271T3 (pl)
ES (1) ES2959690T3 (pl)
FI (1) FI3307271T3 (pl)
HR (1) HRP20231247T1 (pl)
HU (1) HUE063541T2 (pl)
LT (1) LT3307271T (pl)
MA (1) MA44392B1 (pl)
MD (1) MD3307271T2 (pl)
MX (1) MX384883B (pl)
PL (1) PL3307271T3 (pl)
PT (1) PT3307271T (pl)
RS (1) RS64777B1 (pl)
SI (1) SI3307271T1 (pl)
SM (1) SMT202300344T1 (pl)
WO (1) WO2016201227A1 (pl)

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TWI691493B (zh) 2009-06-29 2020-04-21 美商阿吉歐斯製藥公司 治療化合物及組成物
SMT202400081T1 (it) 2011-05-03 2024-03-13 Agios Pharmaceuticals Inc Attivatori della piruvato chinasi per uso in terapia
SMT201900517T1 (it) 2017-03-20 2019-11-13 Forma Therapeutics Inc Composizioni di pirrolopirrolo come attivatori di piruvato chinasi (pkr)
WO2019099651A1 (en) * 2017-11-16 2019-05-23 Agios Pharmaceuticals, Inc. Methods of using deuterated pyruvate kinase activators
LT3713919T (lt) 2017-11-22 2023-10-10 Agios Pharmaceuticals, Inc. Kristalinės n-(4-(4-(ciklopropilmetil)piperazin-1-karbonil)fenil)chinolin-8- sulfonamido formos
CN108169370B (zh) * 2017-12-19 2020-09-04 万舒(北京)医药科技有限公司 测定生物样品中丙酮酸乙酯及其代谢物丙酮酸的方法
CN113166060B (zh) * 2018-09-19 2024-01-09 诺沃挪第克健康护理股份公司 用丙酮酸激酶激活化合物治疗镰状细胞病
US11001588B2 (en) 2018-09-19 2021-05-11 Forma Therapeutics, Inc. Activating pyruvate kinase R and mutants thereof
MX2021014228A (es) 2019-05-22 2022-02-21 Agios Pharmaceuticals Inc Formas cristalinas de sal de n-(4-(4 (ciclopropilmetil)piperazin 1- carbonil)fenil)quinolin-8-sulfonamida.
US11878049B1 (en) 2019-06-14 2024-01-23 Agios Pharmaceuticals, Inc. Mitapivat therapy and modulators of cytochrome P450
CA3151612A1 (en) 2019-09-19 2021-03-25 George P. Luke Pyruvate kinase r (pkr) activating compositions
TW202228691A (zh) 2020-09-25 2022-08-01 美商阿吉歐斯製藥公司 醫藥調配物
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R
WO2022231627A1 (en) 2021-04-30 2022-11-03 Agios Pharmaceuticals, Inc. Methods for titrating mitapivat for use in treating thalassemia
WO2023154036A1 (en) 2022-02-08 2023-08-17 Agios Pharmaceuticals, Inc. Methods for titrating mitapivat
MX2023012823A (es) 2021-04-30 2023-12-07 Agios Pharmaceuticals Inc Métodos para ajustar la dosis de mitapivat.
AU2022390088A1 (en) 2021-11-16 2024-05-09 Agios Pharmaceuticals, Inc. Compounds for treating mds-associated anemias and other conditions

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