PL3178472T3 - Doustne preparaty metylonaltreksonu - Google Patents

Doustne preparaty metylonaltreksonu

Info

Publication number
PL3178472T3
PL3178472T3 PL17153285T PL17153285T PL3178472T3 PL 3178472 T3 PL3178472 T3 PL 3178472T3 PL 17153285 T PL17153285 T PL 17153285T PL 17153285 T PL17153285 T PL 17153285T PL 3178472 T3 PL3178472 T3 PL 3178472T3
Authority
PL
Poland
Prior art keywords
methylnaltrexone
oral formulations
formulations
oral
Prior art date
Application number
PL17153285T
Other languages
English (en)
Polish (pl)
Inventor
Syed M. Shah
Christopher Richard Diorio
Eric C. Ehrnsperger
Xu Meng
Kadum A. Shareffi
Jonathan Marc Cohen
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44148539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3178472(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PL3178472T3 publication Critical patent/PL3178472T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL17153285T 2010-03-11 2011-03-11 Doustne preparaty metylonaltreksonu PL3178472T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31301810P 2010-03-11 2010-03-11
EP17153285.6A EP3178472B1 (en) 2010-03-11 2011-03-11 Oral formulations of methylnaltrexone
EP11157837.3A EP2371357B1 (en) 2010-03-11 2011-03-11 Oral formulations and lipophilic salts of methylnaltrexone

Publications (1)

Publication Number Publication Date
PL3178472T3 true PL3178472T3 (pl) 2022-02-14

Family

ID=44148539

Family Applications (2)

Application Number Title Priority Date Filing Date
PL17153285T PL3178472T3 (pl) 2010-03-11 2011-03-11 Doustne preparaty metylonaltreksonu
PL11157837T PL2371357T3 (pl) 2010-03-11 2011-03-11 Doustne preparaty i lipofilowe sole metylonaltreksonu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11157837T PL2371357T3 (pl) 2010-03-11 2011-03-11 Doustne preparaty i lipofilowe sole metylonaltreksonu

Country Status (32)

Country Link
US (8) US8524276B2 (enExample)
EP (2) EP3178472B1 (enExample)
JP (4) JP6143409B2 (enExample)
KR (2) KR101982482B1 (enExample)
CN (2) CN107308125B (enExample)
AR (1) AR080491A1 (enExample)
AU (1) AU2011224275B2 (enExample)
BR (1) BR112012022873B1 (enExample)
CA (1) CA2789798C (enExample)
CL (1) CL2012002192A1 (enExample)
CO (1) CO6630134A2 (enExample)
CR (1) CR20120476A (enExample)
EA (1) EA029096B1 (enExample)
EC (1) ECSP12012208A (enExample)
ES (1) ES2623926T3 (enExample)
GE (1) GEP201606550B (enExample)
GT (1) GT201200247A (enExample)
HU (1) HUE033133T2 (enExample)
IL (1) IL221452A (enExample)
MA (1) MA34146B1 (enExample)
MX (2) MX368805B (enExample)
MY (1) MY160727A (enExample)
NZ (3) NZ702826A (enExample)
PE (1) PE20130063A1 (enExample)
PH (1) PH12012501622A1 (enExample)
PL (2) PL3178472T3 (enExample)
SG (3) SG183133A1 (enExample)
TN (1) TN2012000392A1 (enExample)
TW (2) TWI605814B (enExample)
UA (2) UA123856C2 (enExample)
WO (1) WO2011112816A1 (enExample)
ZA (1) ZA201808498B (enExample)

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Also Published As

Publication number Publication date
CL2012002192A1 (es) 2012-09-28
US8524276B2 (en) 2013-09-03
AU2011224275B2 (en) 2015-10-01
CA2789798A1 (en) 2011-09-15
PE20130063A1 (es) 2013-02-11
US20140249171A1 (en) 2014-09-04
KR20180118260A (ko) 2018-10-30
IL221452A (en) 2017-07-31
MX368805B (es) 2019-10-17
GEP201606550B (en) 2016-10-10
SG10201501821RA (en) 2015-05-28
MX2012009125A (es) 2012-09-07
BR112012022873A2 (pt) 2016-08-30
US20130330407A1 (en) 2013-12-12
KR101982482B1 (ko) 2019-05-27
US8956651B2 (en) 2015-02-17
SG10201606618PA (en) 2016-09-29
KR20130010900A (ko) 2013-01-29
US20160206612A1 (en) 2016-07-21
US20190314365A1 (en) 2019-10-17
CN107308125A (zh) 2017-11-03
NZ702826A (en) 2016-08-26
TW201141479A (en) 2011-12-01
EP3178472B1 (en) 2021-10-27
CR20120476A (es) 2012-11-30
CN102918039B (zh) 2017-06-09
CO6630134A2 (es) 2013-03-01
EP2371357A1 (en) 2011-10-05
EP2371357B1 (en) 2017-02-01
AR080491A1 (es) 2012-04-11
PL2371357T3 (pl) 2017-09-29
HUE033133T2 (en) 2017-11-28
UA111717C2 (uk) 2016-06-10
TWI605814B (zh) 2017-11-21
EA029096B1 (ru) 2018-02-28
JP6647368B2 (ja) 2020-02-14
GT201200247A (es) 2013-09-11
CN107308125B (zh) 2021-07-16
SG183133A1 (en) 2012-09-27
UA123856C2 (uk) 2021-06-16
MX349145B (es) 2017-07-14
PH12012501622A1 (en) 2012-11-05
US10307417B2 (en) 2019-06-04
CA2789798C (en) 2020-09-22
US20120070495A1 (en) 2012-03-22
EA201270741A1 (ru) 2013-02-28
US20190117646A1 (en) 2019-04-25
EP3178472A1 (en) 2017-06-14
JP2016029054A (ja) 2016-03-03
US10376505B2 (en) 2019-08-13
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JP6143409B2 (ja) 2017-06-07
BR112012022873B1 (pt) 2021-09-14
ECSP12012208A (es) 2015-03-31
JP6429955B2 (ja) 2018-11-28
ES2623926T3 (es) 2017-07-12
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US20190117645A1 (en) 2019-04-25
TW201622724A (zh) 2016-07-01
KR101913102B1 (ko) 2018-10-31
TN2012000392A1 (en) 2014-01-30
WO2011112816A1 (en) 2011-09-15
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JP2011190259A (ja) 2011-09-29
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ZA201808498B (en) 2019-08-28
MA34146B1 (fr) 2013-04-03
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