PL3029144T3 - Zmutowane geny adenowirusowe E1a i E1b o selektywnym działaniu na guza - Google Patents

Zmutowane geny adenowirusowe E1a i E1b o selektywnym działaniu na guza

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Publication number
PL3029144T3
PL3029144T3 PL15182086T PL15182086T PL3029144T3 PL 3029144 T3 PL3029144 T3 PL 3029144T3 PL 15182086 T PL15182086 T PL 15182086T PL 15182086 T PL15182086 T PL 15182086T PL 3029144 T3 PL3029144 T3 PL 3029144T3
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PL
Poland
Prior art keywords
selective action
adenoviral genes
tumor selective
mutated adenoviral
mutated
Prior art date
Application number
PL15182086T
Other languages
English (en)
Polish (pl)
Inventor
Tony Reid
Farah Hedjran
Shantanu Kumar
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of PL3029144T3 publication Critical patent/PL3029144T3/pl

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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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    • C12N15/09—Recombinant DNA-technology
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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PL15182086T 2009-03-02 2010-03-02 Zmutowane geny adenowirusowe E1a i E1b o selektywnym działaniu na guza PL3029144T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15682209P 2009-03-02 2009-03-02
EP10749205.0A EP2403951B1 (en) 2009-03-02 2010-03-02 Tumor-selective adenovirus e1a and e1b mutants
EP15182086.7A EP3029144B1 (en) 2009-03-02 2010-03-02 Tumor-selective adenovirus e1a and e1b mutants
PCT/US2010/025926 WO2010101921A2 (en) 2009-03-02 2010-03-02 Tumor-selective e1a and e1b mutants

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PL3029144T3 true PL3029144T3 (pl) 2020-06-01

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PL15182086T PL3029144T3 (pl) 2009-03-02 2010-03-02 Zmutowane geny adenowirusowe E1a i E1b o selektywnym działaniu na guza
PL10749205T PL2403951T3 (pl) 2009-03-02 2010-03-02 Zmutowane geny adenowirusowe e1a i e1b o selektywnym działaniu na guza

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US (6) US9073980B2 (enExample)
EP (4) EP2403951B1 (enExample)
JP (5) JP6072414B2 (enExample)
KR (4) KR101922539B1 (enExample)
CY (1) CY1122385T1 (enExample)
DK (2) DK3029144T3 (enExample)
ES (2) ES2557812T3 (enExample)
HR (2) HRP20151396T1 (enExample)
HU (2) HUE026386T2 (enExample)
LT (1) LT3029144T (enExample)
PL (2) PL3029144T3 (enExample)
PT (2) PT2403951E (enExample)
SI (2) SI2403951T1 (enExample)
SM (2) SMT201900565T1 (enExample)
WO (1) WO2010101921A2 (enExample)

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DK3029144T3 (da) 2019-10-21
US11618888B2 (en) 2023-04-04
JP2012519014A (ja) 2012-08-23
CY1122385T1 (el) 2021-01-27
EP4123030A1 (en) 2023-01-25
JP2016028035A (ja) 2016-02-25
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HUE026386T2 (en) 2016-06-28
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KR101752910B1 (ko) 2017-06-30
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US20210171917A1 (en) 2021-06-10
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US20190136204A1 (en) 2019-05-09
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