PL2682409T3 - Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym - Google Patents

Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym

Info

Publication number
PL2682409T3
PL2682409T3 PL12752403T PL12752403T PL2682409T3 PL 2682409 T3 PL2682409 T3 PL 2682409T3 PL 12752403 T PL12752403 T PL 12752403T PL 12752403 T PL12752403 T PL 12752403T PL 2682409 T3 PL2682409 T3 PL 2682409T3
Authority
PL
Poland
Prior art keywords
derivative
amino
carboxylic acid
hyaluronic acid
modified
Prior art date
Application number
PL12752403T
Other languages
English (en)
Inventor
Tomoko Yasugi
Yoshihiro Tampo
Kenji Yasugi
Tai Hirakura
Tsuyoshi Shimoboji
Original Assignee
Chugai Seiyaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Seiyaku Kabushiki Kaisha filed Critical Chugai Seiyaku Kabushiki Kaisha
Publication of PL2682409T3 publication Critical patent/PL2682409T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
PL12752403T 2011-03-03 2012-03-02 Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym PL2682409T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011046749 2011-03-03
EP12752403.1A EP2682409B1 (en) 2011-03-03 2012-03-02 Derivative of hyaluronic acid modified with amino-carboxylic acid
PCT/JP2012/055421 WO2012118189A1 (ja) 2011-03-03 2012-03-02 アミノ-カルボン酸により修飾されたヒアルロン酸誘導体

Publications (1)

Publication Number Publication Date
PL2682409T3 true PL2682409T3 (pl) 2017-12-29

Family

ID=46758114

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12752403T PL2682409T3 (pl) 2011-03-03 2012-03-02 Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym

Country Status (9)

Country Link
US (1) US9243077B2 (pl)
EP (2) EP3184553B1 (pl)
JP (2) JP6141180B2 (pl)
DK (1) DK2682409T3 (pl)
ES (1) ES2635087T3 (pl)
HU (1) HUE033169T2 (pl)
PL (1) PL2682409T3 (pl)
SI (1) SI2682409T1 (pl)
WO (1) WO2012118189A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104603156B (zh) * 2012-09-05 2016-10-26 中外制药株式会社 引入有氨基酸和甾基的透明质酸衍生物
US9572832B2 (en) * 2013-08-29 2017-02-21 Holy Stone Healthcare Co., Ltd. Compound of glycosaminoglycan and its fabrication method as well as application
JP6692051B2 (ja) * 2015-02-27 2020-05-13 学校法人常翔学園 膜透過性ペプチド鎖を有する多糖誘導体
JP6613300B2 (ja) * 2015-03-31 2019-11-27 キユーピー株式会社 ヒアルロン酸誘導体およびその製造方法、ならびにヒアルロン酸誘導体を含む化粧料、食品組成物および医薬組成物
EP3252080A1 (en) * 2016-05-31 2017-12-06 Galderma S.A. Method for preparing acylated crosslinked glycosaminoglycans
PL3397651T3 (pl) 2015-12-29 2021-02-08 Galderma S.A. Węglowodanowy środek sieciujący
PT3623390T (pt) * 2016-05-31 2023-10-27 Galderma Sa Reticulador de hidrato de carbono
CN110891611B (zh) 2017-03-22 2024-03-29 阿森迪斯制药公司 水凝胶交联透明质酸前药组合物和方法
US11512147B2 (en) 2017-11-15 2022-11-29 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid derivative modified with polyethylene glycol
CN109206537B (zh) * 2018-10-10 2021-04-09 华熙生物科技股份有限公司 一种乙酰化透明质酸钠的制备方法及其应用
KR20220110786A (ko) 2019-12-02 2022-08-09 갈더마 홀딩 소시에떼 아노님 고분자량 에스테틱 조성물
CN116507575A (zh) 2020-11-12 2023-07-28 三菱电机株式会社 乘客输送机的栏杆

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Publication number Priority date Publication date Assignee Title
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
JP2766303B2 (ja) 1989-04-13 1998-06-18 生化学工業株式会社 グリコサミノグリカンで修飾されたスーパーオキシドジスムターゼ及びその製造法
AU652784B2 (en) 1990-10-18 1994-09-08 Shiseido Company Ltd. Combination of hyaluronic acid with medicinal ingredient and production thereof
JPH0585942A (ja) 1991-02-26 1993-04-06 Denki Kagaku Kogyo Kk インターフエロン−ヒアルロン酸及び/又はその塩の結合体
JP4018181B2 (ja) * 1995-11-07 2007-12-05 生化学工業株式会社 グリコサミノグリカン誘導体およびその製造法
KR20010032879A (ko) 1997-12-12 2001-04-25 익스프레션 제네틱스, 인코퍼레이티드 유전자 담체로서 융합된 공중합체
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
WO2001005434A2 (en) 1999-07-20 2001-01-25 Amgen Inc. Hyaluronic acid-protein conjugates
JP2001081103A (ja) 1999-09-13 2001-03-27 Denki Kagaku Kogyo Kk ヒアルロン酸結合薬剤
WO2001060412A2 (en) 2000-02-15 2001-08-23 Genzyme Corporation Modification of biopolymers for improved drug delivery
EP1666518B1 (en) * 2003-09-08 2018-03-28 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid modification products and drug carriers using them
TW200526253A (en) 2003-11-14 2005-08-16 Chugai Pharmaceutical Co Ltd Cross-linked polysaccharide microparticles and process for producing the same
JPWO2005054302A1 (ja) 2003-12-05 2007-12-06 中外製薬株式会社 薬物担体及びその製造方法
WO2006028110A1 (ja) 2004-09-07 2006-03-16 Chugai Seiyaku Kabushiki Kaisha 水溶性ヒアルロン酸修飾物の製造方法
TW200643033A (en) 2005-03-08 2006-12-16 Chugai Pharmaceutical Co Ltd Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue
CN101679321B (zh) * 2007-04-30 2012-10-03 普罗米蒂克生物科学公司 三嗪衍生物、含所述衍生物的组合物以及所述衍生物在制备用于治疗癌症和自身免疫性疾病药物中的应用
JP5542687B2 (ja) 2008-11-05 2014-07-09 国立大学法人 東京医科歯科大学 ヒアルロン酸誘導体、およびその医薬組成物
IT1399351B1 (it) * 2009-06-16 2013-04-16 Fidia Farmaceutici Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
WO2011148116A2 (fr) 2010-05-27 2011-12-01 Laboratoire Idenov Acide hyaluronique modifie, procede de fabrication et utilisations

Also Published As

Publication number Publication date
EP3184553B1 (en) 2019-05-01
EP2682409A1 (en) 2014-01-08
JP6141180B2 (ja) 2017-06-07
JPWO2012118189A1 (ja) 2014-07-07
WO2012118189A1 (ja) 2012-09-07
EP3184553A1 (en) 2017-06-28
JP2017179374A (ja) 2017-10-05
US9243077B2 (en) 2016-01-26
US20130338352A1 (en) 2013-12-19
ES2635087T3 (es) 2017-10-02
EP2682409A4 (en) 2014-11-19
EP2682409B1 (en) 2017-07-05
DK2682409T3 (en) 2017-09-11
HUE033169T2 (en) 2017-11-28
SI2682409T1 (sl) 2017-08-31

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