PL2173737T3 - Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związki - Google Patents
Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związkiInfo
- Publication number
- PL2173737T3 PL2173737T3 PL08781868T PL08781868T PL2173737T3 PL 2173737 T3 PL2173737 T3 PL 2173737T3 PL 08781868 T PL08781868 T PL 08781868T PL 08781868 T PL08781868 T PL 08781868T PL 2173737 T3 PL2173737 T3 PL 2173737T3
- Authority
- PL
- Poland
- Prior art keywords
- protein
- coupled receptor
- selected compounds
- modulating gpr119
- gpr119
- Prior art date
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95016207P | 2007-07-17 | 2007-07-17 | |
PCT/US2008/070103 WO2009012277A1 (en) | 2007-07-17 | 2008-07-16 | Method for modulating gpr119 g protein-coupled receptor and selected compounds |
EP08781868A EP2173737B1 (en) | 2007-07-17 | 2008-07-16 | Method for modulating gpr119 g protein-coupled receptor and selected compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2173737T3 true PL2173737T3 (pl) | 2012-06-29 |
Family
ID=39864683
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08781868T PL2173737T3 (pl) | 2007-07-17 | 2008-07-16 | Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związki |
PL08781867T PL2170864T3 (pl) | 2007-07-17 | 2008-07-16 | Agoniści receptora gpr119 sprężonego z białkiem g - pirydon |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08781867T PL2170864T3 (pl) | 2007-07-17 | 2008-07-16 | Agoniści receptora gpr119 sprężonego z białkiem g - pirydon |
Country Status (27)
Families Citing this family (51)
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WO2006059778A1 (ja) * | 2004-12-01 | 2006-06-08 | Banyu Pharmaceutical Co., Ltd. | 置換ピリドン誘導体 |
ES2388967T3 (es) | 2007-05-04 | 2012-10-22 | Bristol-Myers Squibb Company | Agonistas [6,6]- y [6,7]-bicíclicos del receptor GPR119 acoplado a la proteína G |
CA2693439A1 (en) * | 2007-07-17 | 2009-01-22 | Bristol-Myers Squibb Company | Pyridone gpr119 g protein-coupled receptor agonists |
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WO2010009195A1 (en) * | 2008-07-16 | 2010-01-21 | Schering Corporation | Bicyclic heterocycle derivatives and use thereof as gpr119 modulators |
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GB0904287D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
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TW201113269A (en) | 2009-06-24 | 2011-04-16 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
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JP2013525489A (ja) | 2010-05-06 | 2013-06-20 | ブリストル−マイヤーズ スクイブ カンパニー | Gpr119修飾因子としての二環式ヘテロアリール類似体 |
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US9359300B2 (en) | 2010-12-06 | 2016-06-07 | Confluence Life Sciences, Inc. | Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds |
WO2014011926A1 (en) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
WO2012123449A1 (en) * | 2011-03-14 | 2012-09-20 | Boehringer Ingelheim International Gmbh | N- cyclopropyl - n- piperidinylbenzamides as gpr119 modulators |
EP2718279B1 (en) | 2011-06-09 | 2016-08-10 | Rhizen Pharmaceuticals SA | Novel compounds as modulators of gpr-119 |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
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CN102993088A (zh) * | 2012-12-31 | 2013-03-27 | 东华大学 | 一种4-羟基-2-吡啶酮的制备方法 |
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2008
- 2008-07-16 CA CA2693439A patent/CA2693439A1/en not_active Abandoned
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