PL2090575T3 - Sposoby i związki pośrednie do otrzymywania pochodnych N4-fenylo-chinazolino-4-aminy - Google Patents

Sposoby i związki pośrednie do otrzymywania pochodnych N4-fenylo-chinazolino-4-aminy

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Publication number
PL2090575T3
PL2090575T3 PL09157031T PL09157031T PL2090575T3 PL 2090575 T3 PL2090575 T3 PL 2090575T3 PL 09157031 T PL09157031 T PL 09157031T PL 09157031 T PL09157031 T PL 09157031T PL 2090575 T3 PL2090575 T3 PL 2090575T3
Authority
PL
Poland
Prior art keywords
quinazoline
intermediates
phenyl
processes
preparation
Prior art date
Application number
PL09157031T
Other languages
English (en)
Polish (pl)
Inventor
Joseph P Lyssikatos
Julie Marie Greschuk
Qian Zhao
Fredrik P Marmsäter
Weidong Lui
David D Hennings
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38022019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2090575(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of PL2090575T3 publication Critical patent/PL2090575T3/pl

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
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PL09157031T 2005-11-15 2006-11-15 Sposoby i związki pośrednie do otrzymywania pochodnych N4-fenylo-chinazolino-4-aminy PL2090575T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73628905P 2005-11-15 2005-11-15
US81701906P 2006-06-28 2006-06-28
EP06837728A EP1971601B1 (en) 2005-11-15 2006-11-15 N4-phenyl-quinazoline-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
EP09157031A EP2090575B1 (en) 2005-11-15 2006-11-15 Processes and intermediates for the preparation of N4-phenyl-quinazoline-4-amine derivatives

Publications (1)

Publication Number Publication Date
PL2090575T3 true PL2090575T3 (pl) 2011-09-30

Family

ID=38022019

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09157031T PL2090575T3 (pl) 2005-11-15 2006-11-15 Sposoby i związki pośrednie do otrzymywania pochodnych N4-fenylo-chinazolino-4-aminy
PL06837728T PL1971601T3 (pl) 2005-11-15 2006-11-15 Pochodne N4-fenylo-chinazolino-4-aminy i związki pokrewne jako inhibitory receptorowych kinaz tyrozynowych ErbB typu I do leczenia chorób cechujących się nadmierną proliferacją komórek

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL06837728T PL1971601T3 (pl) 2005-11-15 2006-11-15 Pochodne N4-fenylo-chinazolino-4-aminy i związki pokrewne jako inhibitory receptorowych kinaz tyrozynowych ErbB typu I do leczenia chorób cechujących się nadmierną proliferacją komórek

Country Status (28)

Country Link
US (6) US8648087B2 (cg-RX-API-DMAC7.html)
EP (2) EP2090575B1 (cg-RX-API-DMAC7.html)
JP (2) JP5134548B2 (cg-RX-API-DMAC7.html)
KR (1) KR101086967B1 (cg-RX-API-DMAC7.html)
CN (2) CN102887891B (cg-RX-API-DMAC7.html)
AT (2) ATE446294T1 (cg-RX-API-DMAC7.html)
AU (2) AU2006315383B2 (cg-RX-API-DMAC7.html)
BR (2) BRPI0618668B1 (cg-RX-API-DMAC7.html)
CA (2) CA2755268C (cg-RX-API-DMAC7.html)
CY (3) CY1110583T1 (cg-RX-API-DMAC7.html)
DE (2) DE602006021645D1 (cg-RX-API-DMAC7.html)
DK (2) DK1971601T3 (cg-RX-API-DMAC7.html)
ES (2) ES2364901T3 (cg-RX-API-DMAC7.html)
FI (1) FIC20210022I1 (cg-RX-API-DMAC7.html)
FR (1) FR21C1031I2 (cg-RX-API-DMAC7.html)
HU (1) HUS2100028I1 (cg-RX-API-DMAC7.html)
IL (2) IL239149A (cg-RX-API-DMAC7.html)
LT (1) LTC1971601I2 (cg-RX-API-DMAC7.html)
LU (1) LUC00217I2 (cg-RX-API-DMAC7.html)
NL (1) NL301113I2 (cg-RX-API-DMAC7.html)
NO (1) NO342413B1 (cg-RX-API-DMAC7.html)
PL (2) PL2090575T3 (cg-RX-API-DMAC7.html)
PT (2) PT1971601E (cg-RX-API-DMAC7.html)
RU (2) RU2428421C2 (cg-RX-API-DMAC7.html)
SG (1) SG152230A1 (cg-RX-API-DMAC7.html)
SI (2) SI1971601T1 (cg-RX-API-DMAC7.html)
WO (1) WO2007059257A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200804498B (cg-RX-API-DMAC7.html)

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US7501427B2 (en) 2003-08-14 2009-03-10 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
CA2535614C (en) 2003-08-14 2009-12-22 Array Biopharma Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
KR101086967B1 (ko) 2005-11-15 2011-11-29 어레이 바이오파마 인크. 과다증식성 질환의 치료를 위한 ｅｒｂｂ 유형 ｉ 수용체티로신 키나제 억제제로서의 ｎ4-페닐-퀴나졸린-4-아민유도체 및 관련 화합물
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
SG174774A1 (en) * 2006-09-11 2011-10-28 Curis Inc Quinazoline based egfr inhibitors containing a zinc binding moiety
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WO2007059257A3 (en) 2007-08-23
JP2009515988A (ja) 2009-04-16
WO2007059257A8 (en) 2007-07-12
PT2090575E (pt) 2011-06-06
ZA200804498B (en) 2009-07-29
SI1971601T1 (sl) 2010-03-31
RU2011122539A (ru) 2012-12-10
CA2632194A1 (en) 2007-05-24
US10780073B2 (en) 2020-09-22
LUC00217I2 (cg-RX-API-DMAC7.html) 2022-10-07
US20110034689A1 (en) 2011-02-10
NL301113I2 (nl) 2021-08-03
ATE507224T1 (de) 2011-05-15
HK1129678A1 (en) 2009-12-04
ES2364901T3 (es) 2011-09-16
SG152230A1 (en) 2009-05-29
CY2021019I2 (el) 2021-12-31
US20140023643A1 (en) 2014-01-23
PT1971601E (pt) 2010-01-26
US20180271824A1 (en) 2018-09-27
RU2428421C2 (ru) 2011-09-10
BRPI0618668B1 (pt) 2021-09-21
AU2006315383A1 (en) 2007-05-24
US8648087B2 (en) 2014-02-11
IL239149A (en) 2016-11-30
JP2010270154A (ja) 2010-12-02
CA2755268A1 (en) 2007-05-24
JP5134548B2 (ja) 2013-01-30
US20210008023A1 (en) 2021-01-14
BRPI0618668A2 (pt) 2011-09-06
NL301113I1 (nl) 2021-07-01
HK1119174A1 (en) 2009-02-27
CA2755268C (en) 2013-12-31
CN101356171A (zh) 2009-01-28
EP1971601B1 (en) 2009-10-21
NO342413B1 (no) 2018-05-22
RU2592703C9 (ru) 2016-10-20
IL239149A0 (en) 2015-07-30
PL1971601T3 (pl) 2010-03-31
RU2008118417A (ru) 2009-12-27
KR20080070064A (ko) 2008-07-29
RU2592703C2 (ru) 2016-07-27
BR122018075851B1 (pt) 2022-01-11
IL248993B (en) 2018-11-29
IL248993A0 (en) 2017-01-31
HUS2100028I1 (hu) 2021-08-30
EP2090575A1 (en) 2009-08-19
US20230142839A1 (en) 2023-05-11
CY1110583T1 (el) 2015-04-29
AU2006315383B2 (en) 2011-06-02
DE602006009968D1 (de) 2009-12-03
US12171739B2 (en) 2024-12-24
JP5232841B2 (ja) 2013-07-10
CY1112754T1 (el) 2016-02-10
EP1971601A2 (en) 2008-09-24
AU2010202330B2 (en) 2012-07-19
CA2632194C (en) 2012-01-03
FR21C1031I2 (fr) 2022-07-15

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