PL202201B1 - Kombinacja farmaceutyczna, jej zastosowanie oraz kompozycja farmaceutyczna zawierająca taką kombinację farmaceutyczną - Google Patents

Kombinacja farmaceutyczna, jej zastosowanie oraz kompozycja farmaceutyczna zawierająca taką kombinację farmaceutyczną

Info

Publication number
PL202201B1
PL202201B1 PL355663A PL35566300A PL202201B1 PL 202201 B1 PL202201 B1 PL 202201B1 PL 355663 A PL355663 A PL 355663A PL 35566300 A PL35566300 A PL 35566300A PL 202201 B1 PL202201 B1 PL 202201B1
Authority
PL
Poland
Prior art keywords
tegaserod
pharmaceutically acceptable
acceptable salt
omeprazole
pharmaceutical
Prior art date
Application number
PL355663A
Other languages
English (en)
Polish (pl)
Other versions
PL355663A1 (en
Inventor
Stephan Anthony Billstein
Peter Dumovic
Nicola Franco
Mark Thomas Iwicki
Hans-Jurgen Pfannkuche
Edward Joseph Wilusz Jr.
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL355663A1 publication Critical patent/PL355663A1/xx
Publication of PL202201B1 publication Critical patent/PL202201B1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL355663A 1999-12-10 2000-12-08 Kombinacja farmaceutyczna, jej zastosowanie oraz kompozycja farmaceutyczna zawierająca taką kombinację farmaceutyczną PL202201B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45838899A 1999-12-10 1999-12-10
PCT/EP2000/012420 WO2001041748A2 (en) 1999-12-10 2000-12-08 Pharmaceutical combinations and their use in treating gastrointestinal disorders

Publications (2)

Publication Number Publication Date
PL355663A1 PL355663A1 (en) 2004-05-04
PL202201B1 true PL202201B1 (pl) 2009-06-30

Family

ID=23820591

Family Applications (1)

Application Number Title Priority Date Filing Date
PL355663A PL202201B1 (pl) 1999-12-10 2000-12-08 Kombinacja farmaceutyczna, jej zastosowanie oraz kompozycja farmaceutyczna zawierająca taką kombinację farmaceutyczną

Country Status (30)

Country Link
EP (3) EP1286668B1 (ru)
JP (1) JP2003523324A (ru)
KR (1) KR100765579B1 (ru)
CN (2) CN1310644C (ru)
AR (1) AR026916A1 (ru)
AT (1) ATE293971T1 (ru)
AU (2) AU778869B2 (ru)
BR (1) BR0016275A (ru)
CA (1) CA2388959A1 (ru)
CO (1) CO5261535A1 (ru)
CZ (1) CZ300690B6 (ru)
DE (1) DE60019814T2 (ru)
DK (1) DK1286668T3 (ru)
ES (1) ES2240229T3 (ru)
HU (1) HUP0301122A3 (ru)
IL (2) IL149496A0 (ru)
MX (1) MXPA02005695A (ru)
MY (1) MY133423A (ru)
NO (1) NO20022680L (ru)
NZ (2) NZ531489A (ru)
PE (1) PE20011030A1 (ru)
PL (1) PL202201B1 (ru)
PT (1) PT1286668E (ru)
RU (1) RU2264215C2 (ru)
SG (1) SG152025A1 (ru)
SK (1) SK8062002A3 (ru)
TR (1) TR200402293T2 (ru)
TW (1) TWI263496B (ru)
WO (1) WO2001041748A2 (ru)
ZA (1) ZA200204493B (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003533482A (ja) * 2000-05-18 2003-11-11 グラクソ グループ リミテッド 機能性消化不良の治療方法
GB0209481D0 (en) * 2002-04-24 2002-06-05 Novartis Ag Organic compounds
DE602004005814T2 (de) 2003-01-13 2008-01-10 Dynogen Pharmaceuticals Inc., Waltham Verfahren zur behandlung von übelkeit, erbrechen, würgereiz oder jede kombination daraus
GB0307440D0 (en) * 2003-03-31 2003-05-07 Novartis Ag Organic compounds
US20060241134A1 (en) * 2003-05-27 2006-10-26 Altana Pharma Ga Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
US20050090554A1 (en) * 2003-09-12 2005-04-28 John Devane Treatment of gastroparesis and nonulcer dyspepsia with GABAB agonists
US7820690B2 (en) 2004-03-19 2010-10-26 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
RU2007105346A (ru) * 2004-07-14 2008-09-27 Новартис АГ (CH) Комбинация ингибиторов dpp-iv и соединений, модулирующих 5-нт3-и/или 5-нт4-рецепторы
JP2008528615A (ja) * 2005-01-31 2008-07-31 ノバルティス アクチエンゲゼルシャフト プロトンポンプ阻害剤により誘発され得る遅延した胃内容排出の処置のための5−ht4アゴニストの使用
GB0506800D0 (en) * 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP2009525269A (ja) 2006-01-30 2009-07-09 ユーロ−セルティーク エス.エイ. カルシウムチャネルブロッカーとしての環状尿素化合物
MX2008015967A (es) * 2006-06-15 2009-01-09 Novartis Ag Composiciones que comprenden tegaserod solo o en combinacion con un inhibidor de la bomba de protones, para el tratamiento o la prevencion de lesion gastrica.
EA200901077A1 (ru) 2007-02-09 2010-04-30 Транзим Фарма, Инк. Макроциклические модуляторы грелинового рецептора и их применение
JP2011503073A (ja) 2007-11-13 2011-01-27 メリテイジ ファーマ,インク. コルチコステロイド組成物
US20090143343A1 (en) 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
WO2018029474A2 (en) 2016-08-09 2018-02-15 Kymab Limited Anti-icos antibodies
KR20230044038A (ko) 2016-08-09 2023-03-31 키맵 리미티드 항-icos 항체
EP3534947A1 (en) 2016-11-03 2019-09-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
GB201709808D0 (en) 2017-06-20 2017-08-02 Kymab Ltd Antibodies
GB201721338D0 (en) 2017-12-19 2018-01-31 Kymab Ltd Anti-icos Antibodies
WO2019122882A1 (en) 2017-12-19 2019-06-27 Kymab Limited Bispecific antibody for icos and pd-l1
WO2022243378A1 (en) 2021-05-18 2022-11-24 Kymab Limited Uses of anti-icos antibodies
GB202107994D0 (en) 2021-06-04 2021-07-21 Kymab Ltd Treatment of cancer
WO2023222854A1 (en) 2022-05-18 2023-11-23 Kymab Limited Uses of anti-icos antibodies
FR3144752A1 (fr) 2023-01-10 2024-07-12 Song Huang Utilisation de polysulfate de pentosane pour le traitement de la toux seche

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT64023A (en) * 1991-03-22 1993-11-29 Sandoz Ag Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds
DK0617620T3 (da) * 1991-12-21 1999-06-07 Smithkline Beecham Plc Anvendelse af 5-HT4-modulatorer til fremstilling af et lægemiddel til behandling af blærelidelser
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US6156771A (en) * 1997-08-28 2000-12-05 Rubin; Walter Method for alleviation of lower gastrointestinal disorders in a human patient
GB9721139D0 (en) * 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
ZA200204493B (en) 2003-09-29
CA2388959A1 (en) 2001-06-14
EP1913944A1 (en) 2008-04-23
CN1409634A (zh) 2003-04-09
KR100765579B1 (ko) 2007-10-09
DE60019814D1 (de) 2005-06-02
CZ300690B6 (cs) 2009-07-15
NZ566800A (en) 2009-11-27
RU2002118316A (ru) 2004-02-20
HUP0301122A2 (hu) 2003-08-28
RU2264215C2 (ru) 2005-11-20
PE20011030A1 (es) 2001-10-31
JP2003523324A (ja) 2003-08-05
WO2001041748A3 (en) 2002-12-19
DE60019814T2 (de) 2006-03-02
BR0016275A (pt) 2002-08-27
NO20022680D0 (no) 2002-06-06
KR20030016208A (ko) 2003-02-26
ES2240229T3 (es) 2005-10-16
SK8062002A3 (en) 2003-04-01
MY133423A (en) 2007-11-30
CO5261535A1 (es) 2003-03-31
CZ20021967A3 (cs) 2002-08-14
AU2005200797B2 (en) 2008-01-24
ATE293971T1 (de) 2005-05-15
IL149496A0 (en) 2002-11-10
EP1286668A2 (en) 2003-03-05
PL355663A1 (en) 2004-05-04
EP1488788A1 (en) 2004-12-22
WO2001041748A2 (en) 2001-06-14
CN1310644C (zh) 2007-04-18
MXPA02005695A (es) 2002-09-18
SG152025A1 (en) 2009-05-29
AU778869B2 (en) 2004-12-23
TR200402293T2 (tr) 2004-10-21
IL149496A (en) 2009-12-24
EP1286668B1 (en) 2005-04-27
AU2005200797A1 (en) 2005-03-17
DK1286668T3 (da) 2005-08-15
TWI263496B (en) 2006-10-11
PT1286668E (pt) 2005-08-31
AU2672801A (en) 2001-06-18
NO20022680L (no) 2002-08-12
HUP0301122A3 (en) 2005-03-29
AR026916A1 (es) 2003-03-05
CN1875966A (zh) 2006-12-13
NZ531489A (en) 2005-09-30

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20101208