PL1852439T3 - Pochodne spiroketalowe i ich zastosowanie jako leku na cukrzycę - Google Patents
Pochodne spiroketalowe i ich zastosowanie jako leku na cukrzycęInfo
- Publication number
- PL1852439T3 PL1852439T3 PL06712450.3T PL06712450T PL1852439T3 PL 1852439 T3 PL1852439 T3 PL 1852439T3 PL 06712450 T PL06712450 T PL 06712450T PL 1852439 T3 PL1852439 T3 PL 1852439T3
- Authority
- PL
- Poland
- Prior art keywords
- diabetic medicine
- spiroketal derivative
- spiroketal
- derivative
- diabetic
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/153—Ortho-condensed systems the condensed system containing two rings with oxygen as ring hetero atom and one ring with nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005020901 | 2005-01-28 | ||
| JP2005176690 | 2005-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1852439T3 true PL1852439T3 (pl) | 2016-10-31 |
Family
ID=36740445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06712450.3T PL1852439T3 (pl) | 2005-01-28 | 2006-01-27 | Pochodne spiroketalowe i ich zastosowanie jako leku na cukrzycę |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7767651B2 (pl) |
| EP (2) | EP3072897B1 (pl) |
| JP (1) | JP4093587B2 (pl) |
| KR (2) | KR20130102648A (pl) |
| AR (1) | AR054612A1 (pl) |
| AU (1) | AU2006209523B2 (pl) |
| BR (1) | BRPI0606367B1 (pl) |
| CA (1) | CA2596235C (pl) |
| CR (1) | CR9314A (pl) |
| DK (1) | DK1852439T3 (pl) |
| ES (1) | ES2567439T3 (pl) |
| HK (1) | HK1111999A1 (pl) |
| HR (1) | HRP20160333T1 (pl) |
| HU (1) | HUE027078T2 (pl) |
| IL (1) | IL184838A (pl) |
| MA (1) | MA29272B1 (pl) |
| MY (1) | MY140528A (pl) |
| NO (1) | NO341263B1 (pl) |
| NZ (1) | NZ556343A (pl) |
| PL (1) | PL1852439T3 (pl) |
| RU (1) | RU2416617C2 (pl) |
| SI (1) | SI1852439T1 (pl) |
| TW (1) | TW200637869A (pl) |
| WO (1) | WO2006080421A1 (pl) |
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| EP2019679B1 (en) * | 2006-05-23 | 2018-06-20 | Theracos, Inc. | Glucose transport inhibitors and methods of use |
| TWI403516B (zh) * | 2006-07-27 | 2013-08-01 | Chugai Pharmaceutical Co Ltd | To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes |
| TWI432446B (zh) * | 2006-07-27 | 2014-04-01 | Chugai Pharmaceutical Co Ltd | 稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用 |
| EP2072522A4 (en) * | 2006-10-13 | 2010-01-06 | Chugai Pharmaceutical Co Ltd | THIOGLUCOSE SPIROCETAL DERIVATIVE AND USE THEREOF AS A THERAPEUTIC AGENT FOR DIABETES |
| US7795228B2 (en) | 2006-12-28 | 2010-09-14 | Theracos, Inc. | Spiroheterocyclic glycosides and methods of use |
| CL2008002427A1 (es) | 2007-08-16 | 2009-09-11 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2. |
| LT2187742T (lt) * | 2007-08-23 | 2018-01-10 | Theracos Sub, Llc | (2s,3r,4r,5s,6r)-2-(4-chlor-3-benzilfenil)-6-(hidroksimetil)tetrahidro-2h-piran-3,4,5-triolio dariniai, skirti panaudoti diabeto gydymui |
| UA101004C2 (en) | 2007-12-13 | 2013-02-25 | Теракос, Инк. | Derivatives of benzylphenylcyclohexane and use thereof |
| JP5820269B2 (ja) | 2008-05-22 | 2015-11-24 | アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ | Ｓｇｌｔ２阻害剤を使用する高尿酸血症の治療方法およびｓｇｌｔ２阻害剤を含有する組成物 |
| TW201011043A (en) | 2008-06-20 | 2010-03-16 | Chugai Pharmaceutical Co Ltd | Crystal of spiroketal derivatives and process for preparation of spiroketal derivatives |
| NZ604897A (en) | 2008-08-22 | 2014-03-28 | Theracos Sub Llc | Processes for the preparation of sglt2 inhibitors |
| AP2728A (en) * | 2008-08-28 | 2013-08-31 | Pfizer | Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives |
| JP5685550B2 (ja) | 2009-02-13 | 2015-03-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｓｇｌｔ２阻害剤、ｄｐｐ−ｉｖ阻害剤、更に必要により抗糖尿病薬を含む医薬組成物及びその使用 |
| JP5696156B2 (ja) | 2009-11-02 | 2015-04-08 | ファイザー・インク | ジオキサ−ビシクロ［３．２．１］オクタン−２，３，４−トリオール誘導体 |
| CN102656177B (zh) * | 2009-12-18 | 2016-01-27 | 中外制药株式会社 | 螺酮缩醇衍生物的制备方法 |
| BR112012025592A2 (pt) | 2010-04-06 | 2019-09-24 | Arena Pharm Inc | moduladores do receptor de gpr119 e o tratamento de distúrbios relacionados com os mesmos |
| WO2011153712A1 (en) | 2010-06-12 | 2011-12-15 | Theracos, Inc. | Crystalline form of benzylbenzene sglt2 inhibitor |
| SG188548A1 (en) | 2010-09-22 | 2013-04-30 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012041898A1 (en) | 2010-09-29 | 2012-04-05 | Celon Pharma Sp. Z O.O. | Combination of sglt2 inhibitor and a sugar compound for the treatment of diabetes |
| WO2012115249A1 (ja) * | 2011-02-25 | 2012-08-30 | 中外製薬株式会社 | スピロケタール誘導体の結晶 |
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| US20140018371A1 (en) | 2011-04-01 | 2014-01-16 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
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| US20140038889A1 (en) | 2011-04-22 | 2014-02-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
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| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| TW201400495A (zh) * | 2012-04-03 | 2014-01-01 | Daiichi Sankyo Co Ltd | 具有螺環之ｃ－醣苷衍生物 |
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| EP3482748A1 (en) * | 2013-12-27 | 2019-05-15 | Chugai Seiyaku Kabushiki Kaisha | Solid preparations containing tofogliflozin and method for producing the same |
| US10346562B2 (en) * | 2014-08-21 | 2019-07-09 | Dassault Systèmes Canada Inc. | Automated curvature modeling of polygonal lines |
| CN106317068A (zh) * | 2015-06-23 | 2017-01-11 | 中国科学院上海药物研究所 | 一种c,o-螺环芳基糖苷类化合物及其制备和应用 |
| EA201990951A1 (ru) | 2016-10-19 | 2019-11-29 | Комбинации, содержащие ssao/vap-1 ингибитор и sglt2-ингибитор, и их применение | |
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| EP3781166A1 (en) | 2018-04-17 | 2021-02-24 | Boehringer Ingelheim International GmbH | Pharmaceutical composition, methods for treating and uses thereof |
| BR112021000139A2 (pt) | 2018-07-19 | 2021-04-06 | Astrazeneca Ab | Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma |
| WO2020039394A1 (en) | 2018-08-24 | 2020-02-27 | Novartis Ag | New drug combinations |
| AU2021230562A1 (en) | 2020-03-06 | 2022-09-22 | Vertex Pharmaceuticals Incorporated | Methods of treating APOL-1 dependent focal segmental glomerulosclerosis |
| US20220023252A1 (en) | 2020-07-27 | 2022-01-27 | Astrazeneca Ab | Methods of treating chronic kidney disease with dapagliflozin |
| AU2022251165A1 (en) | 2021-04-01 | 2023-11-09 | Astrazeneca Uk Limited | Systems and methods for managing prediabetes with a gliflozin sodium-glucose cotransport 2 inhibitor pharmaceutical composition |
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| EA015104B1 (ru) | 2003-08-01 | 2011-06-30 | Мицубиси Танабе Фарма Корпорейшн | Новые соединения, обладающие ингибирующей активностью в отношении натрийзависимого транспортера |
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2006
- 2006-01-25 TW TW095102876A patent/TW200637869A/zh unknown
- 2006-01-26 MY MYPI20060375A patent/MY140528A/en unknown
- 2006-01-27 KR KR1020137020138A patent/KR20130102648A/ko not_active Application Discontinuation
- 2006-01-27 AU AU2006209523A patent/AU2006209523B2/en active Active
- 2006-01-27 KR KR1020077019678A patent/KR101322980B1/ko active IP Right Grant
- 2006-01-27 NZ NZ556343A patent/NZ556343A/en unknown
- 2006-01-27 AR ARP060100301A patent/AR054612A1/es not_active Application Discontinuation
- 2006-01-27 DK DK06712450.3T patent/DK1852439T3/en active
- 2006-01-27 ES ES06712450.3T patent/ES2567439T3/es active Active
- 2006-01-27 US US11/815,074 patent/US7767651B2/en active Active
- 2006-01-27 WO PCT/JP2006/301284 patent/WO2006080421A1/ja active Application Filing
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- 2006-01-27 JP JP2007500586A patent/JP4093587B2/ja active Active
- 2006-01-27 CA CA2596235A patent/CA2596235C/en active Active
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- 2006-01-27 SI SI200632049A patent/SI1852439T1/sl unknown
- 2006-01-27 PL PL06712450.3T patent/PL1852439T3/pl unknown
- 2006-01-27 EP EP16161071.2A patent/EP3072897B1/en active Active
- 2006-01-27 RU RU2007132448/04A patent/RU2416617C2/ru active
- 2006-01-27 EP EP06712450.3A patent/EP1852439B1/en active Active
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- 2007-08-23 NO NO20074310A patent/NO341263B1/no unknown
- 2007-08-28 MA MA30168A patent/MA29272B1/fr unknown
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2008
- 2008-06-24 HK HK08107008.7A patent/HK1111999A1/xx unknown
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2016
- 2016-04-04 HR HRP20160333TT patent/HRP20160333T1/hr unknown
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