PL1661890T3 - Związek aktywujący PPAR oraz kompozycja farmaceutyczna zawierająca ten związek - Google Patents

Związek aktywujący PPAR oraz kompozycja farmaceutyczna zawierająca ten związek

Info

Publication number
PL1661890T3
PL1661890T3 PL04772699T PL04772699T PL1661890T3 PL 1661890 T3 PL1661890 T3 PL 1661890T3 PL 04772699 T PL04772699 T PL 04772699T PL 04772699 T PL04772699 T PL 04772699T PL 1661890 T3 PL1661890 T3 PL 1661890T3
Authority
PL
Poland
Prior art keywords
ppar
pharmaceutical composition
composition containing
containing same
activating compound
Prior art date
Application number
PL04772699T
Other languages
English (en)
Inventor
Yukiyoshi Yamazaki
Tsutomu Toma
Masahiro Nishikawa
Hidefumi Ozawa
Ayumu Okuda
Takaaki Araki
Kazutoyo Abe
Soichi Oda
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of PL1661890T3 publication Critical patent/PL1661890T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL04772699T 2003-09-03 2004-09-02 Związek aktywujący PPAR oraz kompozycja farmaceutyczna zawierająca ten związek PL1661890T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49935703P 2003-09-03 2003-09-03
JP2003317353 2003-09-09
JP2003364817 2003-10-24
EP04772699A EP1661890B1 (en) 2003-09-03 2004-09-02 Ppar-activating compound and pharmaceutical composition containing same
PCT/JP2004/012750 WO2005023777A1 (ja) 2003-09-03 2004-09-02 Ppar活性化化合物及びこれを含有する医薬組成物

Publications (1)

Publication Number Publication Date
PL1661890T3 true PL1661890T3 (pl) 2011-06-30

Family

ID=34279568

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04772699T PL1661890T3 (pl) 2003-09-03 2004-09-02 Związek aktywujący PPAR oraz kompozycja farmaceutyczna zawierająca ten związek

Country Status (17)

Country Link
US (2) US7109226B2 (pl)
EP (1) EP1661890B1 (pl)
JP (2) JP4226005B2 (pl)
KR (1) KR101160808B1 (pl)
AU (1) AU2004270538C1 (pl)
BR (1) BRPI0413991B8 (pl)
CA (1) CA2535749C (pl)
CY (1) CY1111867T1 (pl)
EA (1) EA009374B1 (pl)
HR (1) HRP20110009T1 (pl)
IL (1) IL173639A (pl)
MX (1) MXPA06002435A (pl)
NO (1) NO335823B1 (pl)
NZ (1) NZ545692A (pl)
PL (1) PL1661890T3 (pl)
TW (1) TWI324599B (pl)
WO (1) WO2005023777A1 (pl)

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SI1648922T1 (sl) * 2003-07-31 2011-03-31 Tranzyme Pharma Inc Prostorsko opredeljene makrocikliäśne spojine uporabne za odkrivanje zdravil
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US7301033B2 (en) * 2005-01-27 2007-11-27 Kowa Co., Ltd. PPAR-activating compound
PL1852426T3 (pl) * 2005-02-23 2014-04-30 Kowa Co Sposób wytwarzania optycznie czynnego związku aktywującego PPAR oraz związku pośredniego
EP1854779A4 (en) * 2005-03-01 2010-07-21 Kowa Co OPTICALLY ACTIVE, PPAR-ACTIVATING COMPOSITE INTERMEDIATE PRODUCT AND MANUFACTURING METHOD THEREFOR
ES2342319T3 (es) * 2005-05-31 2010-07-05 Kowa Co., Ltd. Procedimiento para la produccion de compuestos para activar ppar opticamente activos.
WO2007013555A1 (ja) 2005-07-28 2007-02-01 Kowa Co., Ltd. 光学活性2-ヒドロキシ酪酸エステルの製造法
US8088733B2 (en) * 2006-07-06 2012-01-03 Tranzyme Pharma Inc. Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders
WO2008094860A2 (en) * 2007-01-30 2008-08-07 Allergan, Inc. Treating ocular diseases using peroxisome proliferator-activated receptor delta antagonists
TWI407955B (zh) * 2007-03-29 2013-09-11 Kowa Co 高脂血症之預防及/或治療劑
JP5679458B2 (ja) 2009-09-28 2015-03-04 興和株式会社 内臓脂肪重量の低下剤
TWI425948B (zh) * 2012-01-20 2014-02-11 Compositions for the inhibition or killing of Porphyromonas gingivalis and their use for the alleviation or treatment of periodontal disease and other diseases
PL2902025T3 (pl) * 2012-09-27 2020-03-31 Kowa Company Ltd. Środek terapeutyczny przeciwko dyslipidemii
WO2014157607A1 (ja) 2013-03-29 2014-10-02 興和株式会社 2-ヒドロキシカルボン酸又はその誘導体の光学純度向上法
TWI696462B (zh) * 2013-07-10 2020-06-21 日商興和股份有限公司 非酒精性脂肪性肝疾病治療劑
KR20240152981A (ko) 2013-08-28 2024-10-22 교와 가부시키가이샤 지질 이상증 치료제
EP3091970B1 (en) * 2014-01-10 2020-10-28 Rgenix, Inc. Lxr agonists and uses thereof
TWI691331B (zh) * 2014-09-26 2020-04-21 日商興和股份有限公司 脂質異常症治療劑
TW201618777A (zh) * 2014-09-26 2016-06-01 興和股份有限公司 脂質異常症治療劑
JP6850730B2 (ja) * 2015-11-12 2021-03-31 学校法人 聖マリアンナ医科大学 緑内障予防治療剤
ES2847168T5 (es) 2016-07-29 2024-02-20 Kowa Co Métodos para prevenir acontecimientos cardiovasculares en poblaciones dislipidémicas de riesgo residual
JP2019059673A (ja) * 2016-08-25 2019-04-18 興和株式会社 Pbcの治療剤
US20210069157A1 (en) * 2016-08-25 2021-03-11 Kowa Company, Ltd. Agent for treatment of pbc
EP3569250B1 (en) 2017-01-11 2025-04-30 Kowa Company, Ltd. Pemafibrate in combination with a sglt2 inhibitor for the prophylactic or therapeutic treatment of liver diseases nonalcoholic fatty liver disease
US10314825B2 (en) 2017-02-24 2019-06-11 Kowa Company, Ltd. Agent for treatment of PBC
WO2019004466A1 (ja) 2017-06-30 2019-01-03 興和株式会社 医薬
JPWO2019004452A1 (ja) * 2017-06-30 2020-04-30 興和株式会社 医薬組成物
EP3646864A4 (en) 2017-06-30 2021-03-17 Kowa Company, Ltd. PHARMACEUTICAL COMPOSITION CONTAINING PEMAFIBRATE
WO2019004447A1 (ja) * 2017-06-30 2019-01-03 興和株式会社 医薬組成物
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WO2019004448A1 (ja) * 2017-06-30 2019-01-03 興和株式会社 医薬組成物
CN110831591A (zh) * 2017-06-30 2020-02-21 兴和株式会社 医药组合物
JP6959049B2 (ja) * 2017-06-30 2021-11-02 興和株式会社 新規低アルブミン血症改善薬
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WO2019004451A1 (ja) * 2017-06-30 2019-01-03 興和株式会社 医薬組成物
AU2018373028A1 (en) 2017-11-21 2020-04-30 Inspirna, Inc. Polymorphs and uses thereof
US11446282B2 (en) 2017-12-21 2022-09-20 Kowa Company, Ltd. Methods of treating mixed dyslipidemia and hypertriglycertdemia
WO2019126597A1 (en) * 2017-12-21 2019-06-27 Kowa Company, Ltd. Methods of treatment of hypertrigl yceridemia
EP3732168A1 (en) * 2017-12-27 2020-11-04 Teva Pharmaceuticals International GmbH Solid state forms of pemafibrate
JP7356968B2 (ja) 2018-05-08 2023-10-05 国立大学法人 岡山大学 心血管疾患に有用な医薬
WO2020138406A1 (ja) * 2018-12-27 2020-07-02 興和株式会社 医薬組成物
JP2020105174A (ja) * 2018-12-27 2020-07-09 興和株式会社 医薬組成物
EP3903781A4 (en) 2018-12-27 2023-01-25 Kowa Company, Ltd. PHARMACEUTICAL PREPARATION
US20220000786A1 (en) * 2018-12-27 2022-01-06 Kowa Company, Ltd. Pharmaceutical preparation
MX2022007164A (es) 2019-12-13 2022-09-12 Inspirna Inc Sales metálicas y usos de estas.
WO2022224962A1 (ja) 2021-04-20 2022-10-27 興和株式会社 脂質異常症又は心臓血管病の予防・治療のための組合せ医薬
US20240216342A1 (en) 2021-04-28 2024-07-04 Kowa Company, Ltd. Blood carnitine-increasing agent
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Also Published As

Publication number Publication date
IL173639A (en) 2010-12-30
EA200600527A1 (ru) 2006-08-25
TW200524884A (en) 2005-08-01
EP1661890A4 (en) 2008-12-03
TWI324599B (en) 2010-05-11
KR101160808B1 (ko) 2012-06-29
BRPI0413991B8 (pt) 2021-05-25
JPWO2005023777A1 (ja) 2007-11-01
KR20060119890A (ko) 2006-11-24
JP4931893B2 (ja) 2012-05-16
CA2535749A1 (en) 2005-03-17
US7109226B2 (en) 2006-09-19
HRP20110009T1 (hr) 2011-03-31
AU2004270538A1 (en) 2005-03-17
BRPI0413991A (pt) 2006-11-07
US20050101636A1 (en) 2005-05-12
AU2004270538B2 (en) 2009-07-16
JP2009114185A (ja) 2009-05-28
CA2535749C (en) 2011-11-01
EP1661890A1 (en) 2006-05-31
MXPA06002435A (es) 2006-06-20
NO20060654L (no) 2006-04-26
US7183295B2 (en) 2007-02-27
WO2005023777A1 (ja) 2005-03-17
EP1661890B1 (en) 2011-01-05
IL173639A0 (en) 2006-07-05
US20060189667A1 (en) 2006-08-24
CY1111867T1 (el) 2015-11-04
HK1093975A1 (zh) 2007-03-16
BRPI0413991B1 (pt) 2018-09-18
EA009374B1 (ru) 2007-12-28
NO335823B1 (no) 2015-02-23
NZ545692A (en) 2009-02-28
JP4226005B2 (ja) 2009-02-18
AU2004270538C1 (en) 2010-01-14

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