PH27359A - Process for cyclic amino acid anticonvulsant compounds - Google Patents

Process for cyclic amino acid anticonvulsant compounds

Info

Publication number
PH27359A
PH27359A PH41066A PH41066A PH27359A PH 27359 A PH27359 A PH 27359A PH 41066 A PH41066 A PH 41066A PH 41066 A PH41066 A PH 41066A PH 27359 A PH27359 A PH 27359A
Authority
PH
Philippines
Prior art keywords
cyclic amino
amino acid
anticonvulsant compounds
acid anticonvulsant
compounds
Prior art date
Application number
PH41066A
Other languages
English (en)
Inventor
Rex Allen Jennings
Ronald Everest Seamans
James Robert Zeller
Don Richard Johnson
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/564,623 external-priority patent/US5132451A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Priority to PH45082A priority Critical patent/PH30922A/en
Publication of PH27359A publication Critical patent/PH27359A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/10Formation of amino groups in compounds containing carboxyl groups with simultaneously increasing the number of carbon atoms in the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/12Formation of amino and carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/18Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
PH41066A 1989-08-25 1990-08-22 Process for cyclic amino acid anticonvulsant compounds PH27359A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PH45082A PH30922A (en) 1989-08-25 1992-10-12 Process for cyclic amino acid anticonvulsant compound.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39905689A 1989-08-25 1989-08-25
US07/564,623 US5132451A (en) 1989-08-25 1990-08-10 Process for cyclic amino acid anticonvulsant compounds

Publications (1)

Publication Number Publication Date
PH27359A true PH27359A (en) 1993-06-21

Family

ID=27016485

Family Applications (2)

Application Number Title Priority Date Filing Date
PH41066A PH27359A (en) 1989-08-25 1990-08-22 Process for cyclic amino acid anticonvulsant compounds
PH45082A PH30922A (en) 1989-08-25 1992-10-12 Process for cyclic amino acid anticonvulsant compound.

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH45082A PH30922A (en) 1989-08-25 1992-10-12 Process for cyclic amino acid anticonvulsant compound.

Country Status (17)

Country Link
US (1) US5693845A (de)
EP (1) EP0414262B1 (de)
JP (1) JP2945728B2 (de)
AT (1) ATE114637T1 (de)
AU (2) AU633612B2 (de)
CA (1) CA2023874A1 (de)
DE (1) DE69014480T2 (de)
DK (1) DK0414262T3 (de)
ES (1) ES2065446T3 (de)
FI (1) FI107914B (de)
HK (1) HK1000799A1 (de)
IE (1) IE66824B1 (de)
MY (1) MY106864A (de)
NO (1) NO179407C (de)
NZ (1) NZ235044A (de)
PH (2) PH27359A (de)
PT (1) PT95097B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
FI905584A (fi) * 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
AU2001266992B8 (en) * 2000-06-16 2005-12-01 Teva Pharmaceutical Industries Ltd. Stable gabapentin having pH within a controlled range
WO2001097612A1 (en) 2000-06-16 2001-12-27 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 2o ppm of chlorine ion
US20030119908A1 (en) * 2001-12-21 2003-06-26 Zambon Group S.P.A. Stable gabapentin compositions
MXPA05013754A (es) * 2003-06-19 2006-03-08 Pfizer Prod Inc Una preparacion biocatalitica del acido 1-cianociclohexanoacetico.
GB0416228D0 (en) 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
CN101484413B (zh) 2006-06-30 2014-05-14 Zach系统股份公司 制备加巴喷丁的方法
JP4872950B2 (ja) 2008-03-05 2012-02-08 ソニー株式会社 非水電解質二次電池
EP2923694B1 (de) 2014-03-27 2018-11-14 Sanovel Ilac Sanayi ve Ticaret A.S. Orale flüssige pharmazeutische lösung von gabapentin
CN107235850B (zh) * 2017-05-31 2019-07-26 浙江工业大学 利用1-氰基环己基乙酸直接合成加巴喷丁的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2264354A (en) * 1937-12-22 1941-12-02 Ig Farbenindustrie Ag Addition products of dienes and unsaturated esters, ketones, or nitriles
US2467927A (en) * 1947-05-29 1949-04-19 Goodrich Co B F Preparation of monomeric alkyl alpha-cyano-acrylates
US2502412A (en) * 1948-02-07 1950-04-04 Goodrich Co B F Preparation of vinylidene cyanide by pyrolysis of novel 4, 4-disubstituted cyclohexenes
US2575376A (en) * 1949-10-21 1951-11-20 Gen Mills Inc Formyl cyclohexene nitriles and esters
DE1445664A1 (de) * 1963-07-04 1969-11-27 Klinke Desitin Werk Verfahren zur Herstellung von alpha,alpha-disubstituierten Succinimiden
JPS4822692B1 (de) * 1963-12-24 1973-07-07
US3515740A (en) * 1967-02-20 1970-06-02 Orville D Frampton Cyano cyclohexenyl compounds
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
GB1478224A (en) * 1975-01-24 1977-06-29 Science Union & Cie Dispiroalkanes processes for their preparation and pharma ceutical compositions containing them
DE2557220A1 (de) * 1975-12-19 1977-06-23 Goedecke Ag N-substituierte spirolactame
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
DE2626467C2 (de) * 1976-06-12 1984-11-22 Gödecke AG, 1000 Berlin 1-(N-Isopropylaminomethyl)-cyclohexanessigsäure, Verfahren zu deren Herstellung und diese Verbindung enthaltende Arzneimittel
US4226802A (en) * 1979-10-29 1980-10-07 Zoecon Corporation 2-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid esters and intermediates therefor
GB8606255D0 (en) * 1986-03-13 1986-04-16 Wyeth John & Brother Ltd Nitriles
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
YU162789A (en) * 1988-09-01 1990-12-31 Lonza Ag 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones
DE3928184A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte

Also Published As

Publication number Publication date
IE66824B1 (en) 1996-02-07
ES2065446T3 (es) 1995-02-16
EP0414262A2 (de) 1991-02-27
NZ235044A (en) 1994-05-26
PH30922A (en) 1997-12-23
AU3214593A (en) 1993-03-25
AU640582B2 (en) 1993-08-26
DE69014480T2 (de) 1995-04-20
NO903732D0 (no) 1990-08-24
EP0414262B1 (de) 1994-11-30
NO179407C (no) 1996-10-02
PT95097A (pt) 1991-04-18
EP0414262A3 (en) 1991-06-05
PT95097B (pt) 1997-04-30
AU633612B2 (en) 1993-02-04
US5693845A (en) 1997-12-02
FI904164A0 (fi) 1990-08-22
DK0414262T3 (da) 1995-05-15
CA2023874A1 (en) 1991-02-26
FI107914B (fi) 2001-10-31
JPH03236359A (ja) 1991-10-22
NO903732L (no) 1991-02-26
NO179407B (no) 1996-06-24
MY106864A (en) 1995-08-30
HK1000799A1 (en) 1998-05-01
JP2945728B2 (ja) 1999-09-06
IE903094A1 (en) 1991-02-27
ATE114637T1 (de) 1994-12-15
AU6124790A (en) 1991-02-28
DE69014480D1 (de) 1995-01-12

Similar Documents

Publication Publication Date Title
ATE158798T1 (de) Verfahren zur herstellung von optisch aktiven zyklobutannukleosiden
MX22095A (es) Proceso mejorado para compuestos anticonvulsivos de amino acidos ciclicos y productos resultantes.
PH27359A (en) Process for cyclic amino acid anticonvulsant compounds
GEP20012438B (en) Process of Preparing α-Methoxyimino-carboxylic Acid Methylamides and Intermediates Used in the Method
ATE82569T1 (de) Herstellung von chinolincarbonsaeuren.
EP0199646A3 (en) Process for preparing 6-alkoxy-5-trifluoromethyl-1-naphtoic acids and novel 1-cyano-naphtalene intermediates
AU2139792A (en) Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
DE3572969D1 (en) A novel process for the preparation of bestatin derivatives and intermediates thereof
AU556793B2 (en) Sorbinil and methylsorbinil
ATE84518T1 (de) Verfahren zur synthese von 3-chlor-2,4,5trifluorbenzoes|ure.
CA1273347C (de)
ATE46165T1 (de) Verfahren zur herstellung von 7oxabicyclo(2,2,1)hept-5-en-derivaten.
MX9700331A (es) Proceso mejorado para r(+)1,2,3,6-tetrahidro-4-fenil-1-[(3-fenil-3-ciclohexen-1-il)metil]pirid ina, un agente del sistema nervioso central.
HU902026D0 (en) Process for producing 4-methoxy-4-methyl-1-octyne derivatives
ATE87917T1 (de) Verfahren fuer die synthese von athocyanidinen und neues zwischenprodukt.