PH26782A - Process for the production of asymmetric hydantoins - Google Patents

Process for the production of asymmetric hydantoins Download PDF

Info

Publication number
PH26782A
PH26782A PH32670A PH32670A PH26782A PH 26782 A PH26782 A PH 26782A PH 32670 A PH32670 A PH 32670A PH 32670 A PH32670 A PH 32670A PH 26782 A PH26782 A PH 26782A
Authority
PH
Philippines
Prior art keywords
methyl
acid
spiro
amino
fluoro
Prior art date
Application number
PH32670A
Other languages
English (en)
Inventor
Frank John Urban
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH26782A publication Critical patent/PH26782A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Pens And Brushes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Coloring (AREA)
  • Cosmetics (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Indole Compounds (AREA)
PH32670A 1984-08-20 1985-08-20 Process for the production of asymmetric hydantoins PH26782A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64200884A 1984-08-20 1984-08-20

Publications (1)

Publication Number Publication Date
PH26782A true PH26782A (en) 1992-10-13

Family

ID=24574782

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32670A PH26782A (en) 1984-08-20 1985-08-20 Process for the production of asymmetric hydantoins

Country Status (22)

Country Link
US (1) US4716113A (enExample)
EP (1) EP0172719B1 (enExample)
JP (2) JPS6157588A (enExample)
KR (1) KR870000628B1 (enExample)
AT (1) ATE37371T1 (enExample)
AU (1) AU556793B2 (enExample)
DD (2) DD240207A5 (enExample)
DE (1) DE3565105D1 (enExample)
DK (1) DK374985A (enExample)
EG (1) EG17060A (enExample)
ES (1) ES8700259A1 (enExample)
FI (1) FI853183L (enExample)
GR (1) GR851993B (enExample)
HU (3) HU194857B (enExample)
IL (1) IL76131A (enExample)
NO (1) NO853254L (enExample)
NZ (1) NZ213128A (enExample)
PH (1) PH26782A (enExample)
PL (2) PL147253B1 (enExample)
PT (1) PT80985B (enExample)
YU (1) YU43879B (enExample)
ZA (1) ZA856267B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006657A (en) * 1988-07-27 1991-04-09 Pfizer Inc. Intermediates in a resolution process for racemic spiro hydantoins
US4952694A (en) * 1988-07-27 1990-08-28 Pfizer Inc. Novel resolution process for racemic spiro-hydantoins
US5151544A (en) * 1990-05-25 1992-09-29 Alcon Laboratories, Inc. Intermediates in the preparation of chiral spirofluorenehydantoins
US5206367A (en) * 1992-02-18 1993-04-27 Pfizer Inc. Preparation of optically active spiro-hydantoins
US5508466A (en) * 1994-04-13 1996-04-16 G.D. Searle & Co. Synthesis of N-protected-α-substituted-glycine racemic esters by zinc-mediated addition of organic halide to glycine cation equivalent
WO2014126071A1 (ja) * 2013-02-12 2014-08-21 国立大学法人大阪大学 芳香族アミノ酸誘導体およびそれを用いるｐｅｔプローブ

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878043A (en) * 1973-01-02 1975-04-15 Univ Southern Illinois Method for preparing L-dopa and novels compounds useful therein
DE2336718A1 (de) * 1973-07-19 1975-02-06 Basf Ag Verfahren zur herstellung von substituierten oxazolinon-(5)-verbindungen
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
DE2807286A1 (de) * 1978-02-21 1979-08-23 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten und 4-hydroxyphenylglycinderivaten mit enzymharzen
US4267342A (en) * 1978-08-21 1981-05-12 Pfizer Inc. Spiro-oxazolidindiones
US4262092A (en) * 1979-05-08 1981-04-14 Ethyl Corporation Process for producing N-acyl-D-phenylalanine ester
DE2927535A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten mit enzymharzen
DE2927534A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
GB2098212B (en) * 1981-05-12 1984-11-14 Ici Plc Process for preparing 1'-substituted-spiro(imidazolidine)-4,3'-indoline-2,2',5-triones
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4474967A (en) * 1983-04-27 1984-10-02 Pfizer Inc. 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives

Also Published As

Publication number Publication date
NO853254L (no) 1986-02-21
ATE37371T1 (de) 1988-10-15
KR870000628B1 (ko) 1987-03-26
AU556793B2 (en) 1986-11-20
EG17060A (en) 1991-03-30
PL255065A1 (en) 1986-11-04
HUT43577A (en) 1987-11-30
HU201042B (en) 1990-09-28
PL147253B1 (en) 1989-05-31
PT80985A (en) 1985-09-01
FI853183A0 (fi) 1985-08-19
EP0172719A1 (en) 1986-02-26
US4716113A (en) 1987-12-29
PL148572B1 (en) 1989-10-31
HUT46316A (en) 1988-10-28
HU193127B (en) 1987-08-28
JPS6157588A (ja) 1986-03-24
AU4641485A (en) 1986-02-27
DK374985D0 (da) 1985-08-19
JPS6362512B2 (enExample) 1988-12-02
KR870002142A (ko) 1987-03-30
HUT39745A (en) 1986-10-29
FI853183A7 (fi) 1986-02-21
ZA856267B (en) 1987-04-29
ES8700259A1 (es) 1986-10-01
EP0172719B1 (en) 1988-09-21
DD254005A5 (de) 1988-02-10
ES546294A0 (es) 1986-10-01
JPS63290873A (ja) 1988-11-28
PT80985B (pt) 1987-12-30
YU43879B (en) 1989-12-31
GR851993B (enExample) 1985-12-17
YU131985A (en) 1988-04-30
DD240207A5 (de) 1986-10-22
IL76131A0 (en) 1985-12-31
HU194857B (en) 1988-03-28
PL260564A1 (en) 1987-02-09
DK374985A (da) 1986-02-21
IL76131A (en) 1989-01-31
DE3565105D1 (en) 1988-10-27
NZ213128A (en) 1988-02-29
FI853183L (fi) 1986-02-21

Similar Documents

Publication Publication Date Title
US5514804A (en) Diastereomer salt of optically active quinolinemevalonic acid
EP0045118A2 (en) Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2Z-enes
RU2094428C1 (ru) Способ получения бензопирановых соединений, промежуточные соединения и способы их получения
EP0139809B1 (en) Substituted dihydrobenzopyrans
PH26782A (en) Process for the production of asymmetric hydantoins
US4841079A (en) Process for the production of asymmetric hydantoins
US4118401A (en) Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor
US4158012A (en) Steroid synthesis process using mixed anhydride
US4353911A (en) Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow
US5066826A (en) Process for racemization of optically active 4-phenylbutanoic acid esters
JPS6317077B2 (enExample)
Uskoković et al. The Stereoselectivity of Ketone Reduction with Sporotrichum Exile. Resolution of cis‐and trans‐2‐benzoyloctahydro‐6 (2H)‐isoquinolones
US4201870A (en) Process for the preparation of 2-(3-benzoylphenyl)-propionic acid
US4175209A (en) Preparation of 6,11-dihydro-11-oxodibenz[b,e]-oxepin-2-acetic acid and precursors therefor
JPS644508B2 (enExample)
SU439089A3 (ru) Способ получения 3-оксо-19-нор-а4-стероидов
EP0110496A2 (en) Improvements in keto intermediates, their use and preparation
KR820000581B1 (ko) 6,11-디하이드로-11 옥소디벤즈 [b,e]-옥세핀-2-아세트산의 제조방법
US4234491A (en) Steroid synthesis process using mixed anhydride
GB2163160A (en) Process for the preparation of an aminolactone
EP0245913B1 (en) Process for preparing 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid
US4568749A (en) Certain 5-aryl-2-[(4-aryl)-4-hydroxybutyn-2-yl]-1,2,3,4-γ-carbolines
KR820000475B1 (ko) 6,11-디하이드로-11 옥소디벤즈[b,e]-옥세핀-2-아세트산의 제조방법
JPS6270368A (ja) 置換１−ベンゾピラン−２−イル−プロパン酸
JPH11302216A (ja) ジアルコキシ置換インダノン誘導体の製造方法