PH26358A - 5-(substituted-amino)-8-(phenyl or substitutedphenyl)-3H, 6H-1,4 5A,8A-tetraazaacenaphthylen-3-ones and treatment of neutral behavior disorders - Google Patents

5-(substituted-amino)-8-(phenyl or substitutedphenyl)-3H, 6H-1,4 5A,8A-tetraazaacenaphthylen-3-ones and treatment of neutral behavior disorders Download PDF

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Publication number
PH26358A
PH26358A PH38218A PH38218A PH26358A PH 26358 A PH26358 A PH 26358A PH 38218 A PH38218 A PH 38218A PH 38218 A PH38218 A PH 38218A PH 26358 A PH26358 A PH 26358A
Authority
PH
Philippines
Prior art keywords
phenyl
tetraazaacenaphthylen
trifluoromethyl
mixture
stirred
Prior art date
Application number
PH38218A
Other languages
English (en)
Inventor
Joseph William Epstein
Jeremy Ian Levin
Shin Shyong Tseng
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH26358A publication Critical patent/PH26358A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PH38218A 1988-02-22 1989-02-20 5-(substituted-amino)-8-(phenyl or substitutedphenyl)-3H, 6H-1,4 5A,8A-tetraazaacenaphthylen-3-ones and treatment of neutral behavior disorders PH26358A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15844888A 1988-02-22 1988-02-22

Publications (1)

Publication Number Publication Date
PH26358A true PH26358A (en) 1992-04-29

Family

ID=22568168

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38218A PH26358A (en) 1988-02-22 1989-02-20 5-(substituted-amino)-8-(phenyl or substitutedphenyl)-3H, 6H-1,4 5A,8A-tetraazaacenaphthylen-3-ones and treatment of neutral behavior disorders

Country Status (23)

Country Link
EP (1) EP0329940B1 (cs)
JP (1) JP2641556B2 (cs)
KR (1) KR970009226B1 (cs)
AR (1) AR247211A1 (cs)
AT (1) ATE99686T1 (cs)
AU (1) AU611769B2 (cs)
CA (1) CA1329594C (cs)
CZ (1) CZ284273B6 (cs)
DD (1) DD283624A5 (cs)
DE (1) DE68911951T2 (cs)
DK (1) DK172397B1 (cs)
ES (1) ES2061739T3 (cs)
FI (1) FI89922C (cs)
HU (1) HU203554B (cs)
IE (1) IE64147B1 (cs)
IL (1) IL88974A (cs)
NO (1) NO169589C (cs)
NZ (1) NZ228009A (cs)
PH (1) PH26358A (cs)
PL (1) PL158865B1 (cs)
PT (1) PT89766B (cs)
SK (1) SK105589A3 (cs)
ZA (1) ZA891310B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
SG47588A1 (en) * 1992-03-26 1998-04-17 American Cyanamid Co An improved process for the synthesis of 5-[(substituted) amino] -8- [phenyl or substituted-phenyl]-3H, 6H-1, 4, 5A, 8A-tetraazaacenaphtylen-3- ones
AU5611398A (en) * 1996-12-19 1998-07-15 American Cyanamid Company Method of treating or inhibiting neutropenia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
EP0264773A1 (en) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines

Also Published As

Publication number Publication date
JP2641556B2 (ja) 1997-08-13
CZ284273B6 (cs) 1998-10-14
ATE99686T1 (de) 1994-01-15
HU203554B (en) 1991-08-28
ZA891310B (en) 1989-11-29
NO169589B (no) 1992-04-06
PL277837A1 (en) 1989-11-13
PT89766B (pt) 1994-03-31
DE68911951T2 (de) 1994-06-01
AU3017289A (en) 1989-08-24
DK172397B1 (da) 1998-05-18
KR890013022A (ko) 1989-09-20
DE68911951D1 (de) 1994-02-17
KR970009226B1 (en) 1997-06-09
SK279319B6 (sk) 1998-09-09
FI89922B (fi) 1993-08-31
ES2061739T3 (es) 1994-12-16
FI890826A7 (fi) 1989-08-23
NO890724D0 (no) 1989-02-21
CZ105589A3 (cs) 1998-07-15
FI89922C (fi) 1993-12-10
SK105589A3 (en) 1998-09-09
IL88974A (en) 1993-03-15
DK79589D0 (da) 1989-02-21
EP0329940A1 (en) 1989-08-30
CA1329594C (en) 1994-05-17
NO169589C (no) 1992-07-15
AR247211A1 (es) 1994-11-30
IE890543L (en) 1989-08-22
FI890826A0 (fi) 1989-02-21
HUT51626A (en) 1990-05-28
IL88974A0 (en) 1989-08-15
PT89766A (pt) 1989-10-04
PL158865B1 (pl) 1992-10-30
EP0329940B1 (en) 1994-01-05
DD283624A5 (de) 1990-10-17
AU611769B2 (en) 1991-06-20
IE64147B1 (en) 1995-07-12
NZ228009A (en) 1991-09-25
DK79589A (da) 1989-08-23
JPH01249774A (ja) 1989-10-05
NO890724L (no) 1989-08-23

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