PH24741A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
PH24741A
PH24741A PH34698A PH34698A PH24741A PH 24741 A PH24741 A PH 24741A PH 34698 A PH34698 A PH 34698A PH 34698 A PH34698 A PH 34698A PH 24741 A PH24741 A PH 24741A
Authority
PH
Philippines
Prior art keywords
indole derivatives
indole
derivatives
Prior art date
Application number
PH34698A
Other languages
English (en)
Inventor
Colin David Eldred
Keith Mills
Ian Harold Coates
David Edmund Bays
Michael Dennis Dowle
Colin Frederick Webb
Alexander William Oxford
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PH24741A publication Critical patent/PH24741A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH34698A 1986-01-08 1987-01-08 Indole derivatives PH24741A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (1)

Publication Number Publication Date
PH24741A true PH24741A (en) 1990-10-01

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34698A PH24741A (en) 1986-01-08 1987-01-08 Indole derivatives

Country Status (23)

Country Link
US (1) US4855314A (it)
EP (1) EP0240096A1 (it)
JP (1) JPS62228056A (it)
KR (1) KR870007116A (it)
CN (1) CN1030409A (it)
AU (1) AU597325B2 (it)
BE (1) BE1000071A4 (it)
CH (1) CH672637A5 (it)
DE (1) DE3700408A1 (it)
DK (1) DK8787A (it)
FI (1) FI870062A (it)
FR (1) FR2595351B1 (it)
GB (2) GB8600397D0 (it)
HU (1) HU198685B (it)
IL (1) IL81201A (it)
IT (1) IT1205849B (it)
LU (1) LU86732A1 (it)
NL (1) NL8700026A (it)
NO (1) NO870075L (it)
NZ (1) NZ218868A (it)
PH (1) PH24741A (it)
PT (1) PT84075B (it)
ZA (1) ZA87105B (it)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
CZ288351B6 (en) * 1990-06-07 2001-05-16 Astrazeneca Ab Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
HU225055B1 (en) * 1990-10-15 2006-05-29 Pfizer Indole derivatives, their intermediates, process for production them and pharmaceutical compositions containing the compounds
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
JP2840448B2 (ja) * 1991-11-25 1998-12-24 フアイザー・インコーポレイテツド インドール誘導体
TW288010B (it) * 1992-03-05 1996-10-11 Pfizer
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
SK280193B6 (sk) 1992-04-07 1999-09-10 Pfizer Inc. Indolové deriváty predstavujúce 5-ht1 agonisty, fa
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
ES2097496T3 (es) * 1992-04-10 1997-04-01 Pfizer Derivados acilaminoindol como agonistas de 5-ht1.
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (it) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
US5849739A (en) * 1993-08-31 1998-12-15 Pfizer Inc. 5-arylindole derivatives
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
JP2004506714A (ja) * 2000-08-21 2004-03-04 パシフィック コーポレーション 新規チオ尿素化合物及びこれを含有する薬学的組成物
SI1517909T1 (sl) 2002-06-21 2007-06-30 Suven Life Sciences Ltd Novi tetraciklični arilkarbonil indoli, ki imajo afiniteto za serotoninski receptor, uporabni kot terapevtska sredstva, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo
DK1523486T3 (da) * 2002-06-21 2008-03-03 Suven Life Sciences Ltd Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet
WO2004000845A1 (en) * 2002-06-21 2003-12-31 Suven Life Sciences Limited Arylalkyl indoles having sertonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
BRPI0315959C1 (pt) * 2002-11-28 2021-05-25 Suven Life Sciences Ltd composto, composição farmacêutica, uso do composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso e processo para a preparação do composto
ES2425143T3 (es) 2002-11-28 2013-10-11 Suven Life Sciences Limited N-Arilsulfonil-3-aminoalcoxiindoles
ATE355292T1 (de) * 2002-12-18 2006-03-15 Suven Life Sciences Ltd Tetrazyklische 3-substituierte indole mit serotoninrezeptoraffinität
EP1572647B1 (en) * 2002-12-20 2016-09-21 Basf Se Synthesis of amines and intermediates for the synthesis thereof
MY147013A (en) * 2006-06-12 2012-10-15 Novartis Ag Process for making salts of n-hydroxy-3-[4-[[[2-(2-methyl-1h-indol-3-yl)ethyl]amino]methyl]phenyl]-2e-2-propenamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
DE3131752A1 (de) * 1980-08-12 1982-06-16 Glaxo Group Ltd., London Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
GB2185020A (en) 1987-07-08
GB8700382D0 (en) 1987-02-11
CH672637A5 (it) 1989-12-15
NZ218868A (en) 1990-04-26
GB2185020B (en) 1990-05-16
JPS62228056A (ja) 1987-10-06
CN1030409A (zh) 1989-01-18
FR2595351A1 (fr) 1987-09-11
FI870062A0 (fi) 1987-01-08
PT84075B (pt) 1989-07-31
IT8747507A0 (it) 1987-01-08
IT1205849B (it) 1989-03-31
LU86732A1 (fr) 1988-02-02
NL8700026A (nl) 1987-08-03
HUT46891A (en) 1988-12-28
DK8787A (da) 1987-07-09
ZA87105B (en) 1987-09-30
KR870007116A (ko) 1987-08-14
BE1000071A4 (fr) 1988-02-02
DK8787D0 (da) 1987-01-08
NO870075L (no) 1987-07-09
EP0240096A1 (en) 1987-10-07
US4855314A (en) 1989-08-08
IL81201A (en) 1991-06-10
NO870075D0 (no) 1987-01-08
DE3700408A1 (de) 1987-07-09
HU198685B (en) 1989-11-28
AU6742087A (en) 1987-07-09
FI870062A (fi) 1987-07-09
AU597325B2 (en) 1990-05-31
FR2595351B1 (fr) 1990-07-13
IL81201A0 (en) 1987-08-31
GB8600397D0 (en) 1986-02-12
PT84075A (en) 1987-02-01

Similar Documents

Publication Publication Date Title
GB2185020B (en) Indole derivatives
ZA885923B (en) Indole derivatives
PH22850A (en) Indole derivatives
EP0253500A3 (en) Acylanilide derivatives
GB2168973B (en) Indole derivatives
ZA864770B (en) Indole derivatives
GB2186874B (en) Indole derivatives
ZA854355B (en) Indole derivatives
EP0247381A3 (en) 5-flurorouracil derivatives
GB2191488B (en) Indole derivatives
ZA874622B (en) Indole derivatives
AR245109A1 (es) Un procedimiento para la preparacion de 5-fenil-5h-indeno/1,2-d/ pirimidina.
GB8620237D0 (en) Indole derivatives
EP0246002A3 (en) Alkenamide derivatives
GB2184443B (en) Indole derivatives
GB2184444B (en) Indole derivatives
EP0267024A3 (en) Hydrofluorene derivatives
GB8614325D0 (en) Indole derivatives
GB8601960D0 (en) Indole derivatives
IE861722L (en) Indole derivatives
ZA859244B (en) Indole derivatives
EP0244193A3 (en) Dihalogen-substituted thiocyanopyrimidine derivatives
ZA873138B (en) Indole derivative
GB8706269D0 (en) Indole derivatives
IE870688L (en) Indole derivatives