GB2186874B - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
GB2186874B
GB2186874B GB8700381A GB8700381A GB2186874B GB 2186874 B GB2186874 B GB 2186874B GB 8700381 A GB8700381 A GB 8700381A GB 8700381 A GB8700381 A GB 8700381A GB 2186874 B GB2186874 B GB 2186874B
Authority
GB
United Kingdom
Prior art keywords
indole derivatives
indole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8700381A
Other versions
GB2186874A (en
GB8700381D0 (en
Inventor
Keith Mills
David Edmund Bays
Colin Frederick Webb
Ian Harold Coates
Michael Dennis Dowle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GB8700381D0 publication Critical patent/GB8700381D0/en
Publication of GB2186874A publication Critical patent/GB2186874A/en
Application granted granted Critical
Publication of GB2186874B publication Critical patent/GB2186874B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
GB8700381A 1986-01-08 1987-01-08 Indole derivatives Expired - Fee Related GB2186874B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600398A GB8600398D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (3)

Publication Number Publication Date
GB8700381D0 GB8700381D0 (en) 1987-02-11
GB2186874A GB2186874A (en) 1987-08-26
GB2186874B true GB2186874B (en) 1990-02-07

Family

ID=10591075

Family Applications (2)

Application Number Title Priority Date Filing Date
GB868600398A Pending GB8600398D0 (en) 1986-01-08 1986-01-08 Chemical compounds
GB8700381A Expired - Fee Related GB2186874B (en) 1986-01-08 1987-01-08 Indole derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB868600398A Pending GB8600398D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Country Status (11)

Country Link
JP (1) JPS62228057A (en)
AT (1) AT386197B (en)
AU (1) AU597324B2 (en)
BE (1) BE1000072A4 (en)
CH (1) CH671017A5 (en)
DE (1) DE3700407A1 (en)
FR (1) FR2595352B1 (en)
GB (2) GB8600398D0 (en)
IT (1) IT1216772B (en)
NL (1) NL8700027A (en)
ZA (1) ZA87104B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2110517C1 (en) * 1990-06-07 1998-05-10 Дзе Веллкам Фаундейшн Лимитед N,n-dimethyl-2-(5-(2-oxo-1,3-oxazolidine-4-yl-methyl)-1h-indo- -le-3-yl)-ethylamine, its physiologically acceptable salt or solvate, method of its synthesis, drug used as an agonist of "5-ht1-like" receptor in mammals, method of drug agent preparing

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
SK281621B6 (en) * 1990-06-07 2001-05-10 Astrazeneca Ab Therapeutic heterocyclic compounds
TW263508B (en) * 1991-02-12 1995-11-21 Pfizer
US5206377A (en) * 1991-12-05 1993-04-27 Whitby Research, Inc. Compounds useful as antiproliferative agents
GB9201038D0 (en) * 1992-01-16 1992-03-11 Glaxo Group Ltd Chemical compounds
US5409941A (en) * 1992-02-03 1995-04-25 Pfizer Inc. 5-heteroyl indole derivatives
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
CA2147991A1 (en) * 1993-09-01 1995-03-09 Richard A. Glennon Tryptamine analogs with 5-ht1d selectivity
US5496957A (en) * 1993-09-01 1996-03-05 Virginia Commonwealth University Tryptamine analogs with 5-HT1D selectivity
CA2508290C (en) 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2081717A (en) * 1980-08-12 1982-02-24 Glaxo Group Ltd Hereocyclic compounds
GB2083463A (en) * 1980-08-12 1982-03-24 Glaxo Group Ltd Heterocyclic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB147107A (en) * 1915-04-06 1921-10-07 Zeiss Carl Improvements in finders for photographic apparatus
GB145459A (en) * 1917-03-24 1921-04-21 Anschuetz & Co Gmbh Improvements in indicators for the turning of aircraft about a vertical axis
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
FR2903394B1 (en) * 2006-07-05 2008-09-19 Pierre Marcelli EXPANDABLE CHUCK REEL FOR SPOOL
EP2150932A1 (en) * 2007-04-06 2010-02-10 Gaiasoft IP Limited Content delivery system and method of delivering content

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2081717A (en) * 1980-08-12 1982-02-24 Glaxo Group Ltd Hereocyclic compounds
GB2083463A (en) * 1980-08-12 1982-03-24 Glaxo Group Ltd Heterocyclic compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2110517C1 (en) * 1990-06-07 1998-05-10 Дзе Веллкам Фаундейшн Лимитед N,n-dimethyl-2-(5-(2-oxo-1,3-oxazolidine-4-yl-methyl)-1h-indo- -le-3-yl)-ethylamine, its physiologically acceptable salt or solvate, method of its synthesis, drug used as an agonist of "5-ht1-like" receptor in mammals, method of drug agent preparing

Also Published As

Publication number Publication date
DE3700407A1 (en) 1987-07-09
GB8600398D0 (en) 1986-02-12
IT1216772B (en) 1990-03-14
JPS62228057A (en) 1987-10-06
IT8747506A0 (en) 1987-01-08
AU597324B2 (en) 1990-05-31
FR2595352B1 (en) 1990-07-13
GB2186874A (en) 1987-08-26
NL8700027A (en) 1987-08-03
GB8700381D0 (en) 1987-02-11
ATA2487A (en) 1987-12-15
BE1000072A4 (en) 1988-02-02
ZA87104B (en) 1987-12-30
FR2595352A1 (en) 1987-09-11
AT386197B (en) 1988-07-11
CH671017A5 (en) 1989-07-31
AU6741887A (en) 1987-07-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930108