DK8787D0 - Indolderivater og fremgangsmaade til fremstilling deraf - Google Patents

Indolderivater og fremgangsmaade til fremstilling deraf

Info

Publication number
DK8787D0
DK8787D0 DK008787A DK8787A DK8787D0 DK 8787 D0 DK8787 D0 DK 8787D0 DK 008787 A DK008787 A DK 008787A DK 8787 A DK8787 A DK 8787A DK 8787 D0 DK8787 D0 DK 8787D0
Authority
DK
Denmark
Prior art keywords
procedures
preparing
index derivatives
derivatives
index
Prior art date
Application number
DK008787A
Other languages
English (en)
Other versions
DK8787A (da
Inventor
Keith Mills
Colin David Eldred
Alexander William Oxford
Ian Harold Coates
David Edmund Bays
Colin Frederick Webb
Michael Dennis Dowle
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK8787D0 publication Critical patent/DK8787D0/da
Publication of DK8787A publication Critical patent/DK8787A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK008787A 1986-01-08 1987-01-08 Indolderivater og fremgangsmaade til fremstilling deraf DK8787A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (2)

Publication Number Publication Date
DK8787D0 true DK8787D0 (da) 1987-01-08
DK8787A DK8787A (da) 1987-07-09

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
DK008787A DK8787A (da) 1986-01-08 1987-01-08 Indolderivater og fremgangsmaade til fremstilling deraf

Country Status (23)

Country Link
US (1) US4855314A (da)
EP (1) EP0240096A1 (da)
JP (1) JPS62228056A (da)
KR (1) KR870007116A (da)
CN (1) CN1030409A (da)
AU (1) AU597325B2 (da)
BE (1) BE1000071A4 (da)
CH (1) CH672637A5 (da)
DE (1) DE3700408A1 (da)
DK (1) DK8787A (da)
FI (1) FI870062A7 (da)
FR (1) FR2595351B1 (da)
GB (2) GB8600397D0 (da)
HU (1) HU198685B (da)
IL (1) IL81201A (da)
IT (1) IT1205849B (da)
LU (1) LU86732A1 (da)
NL (1) NL8700026A (da)
NO (1) NO870075L (da)
NZ (1) NZ218868A (da)
PH (1) PH24741A (da)
PT (1) PT84075B (da)
ZA (1) ZA87105B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
SI9111010B (sl) * 1990-06-07 2005-02-28 Astrazeneca Ab 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
PL168919B1 (pl) * 1990-10-15 1996-05-31 Pfizer Sposób wytwarzania nowych pochodnych indolu PL PL PL PL
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
CA2124206C (en) * 1991-11-25 2001-02-27 John Eugene Macor Indole derivatives
TW288010B (da) * 1992-03-05 1996-10-11 Pfizer
RU2101283C1 (ru) 1992-04-07 1998-01-10 Пфайзер Инк. Производные индола или их фармацевтически приемлемые соли
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
AU670270B2 (en) * 1992-04-10 1996-07-11 Pfizer Inc. Acylaminoindole derivatives as 5-HT1 agonists
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (da) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
CN1129933A (zh) * 1993-08-31 1996-08-28 辉瑞大药厂 5-芳基吲哚衍生物
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
JP2004506714A (ja) * 2000-08-21 2004-03-04 パシフィック　コーポレーション 新規チオ尿素化合物及びこれを含有する薬学的組成物
BR0312176A (pt) * 2002-06-21 2005-04-05 Suven Life Sciences Ltd Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario
MXPA04012834A (es) * 2002-06-21 2005-04-25 Suven Life Sciences Ltd Arilalquil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
DE60309324T2 (de) 2002-06-21 2007-05-10 Suven Life Sciences Ltd. Tetracyclische arylcarbonyl indole mit serotoninrezeptoraffinität als arzneimittel, verfahren zu ihrer herstellung und pharmazeutische zubereitungen
EP1581492B1 (en) * 2002-11-28 2008-07-16 Suven Life Sciences Limited N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
KR100776118B1 (ko) 2002-11-28 2007-11-15 수벤 라이프 사이언시스 리미티드 엔-아릴술포닐-3-아미노알콕시인돌
AU2003292510B2 (en) * 2002-12-18 2009-04-23 Suven Life Sciences Limited Tetracyclic 3-substituted indoles having serotonin receptor affinity
CA2508290C (en) * 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
EP2032532B8 (en) 2006-06-12 2015-07-01 Novartis AG Process for making salts of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
FR2488606A1 (fr) * 1980-08-12 1982-02-19 Glaxo Group Ltd Derives indoliques, leur preparation et leurs applications en tant que medicaments
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
LU86732A1 (fr) 1988-02-02
IL81201A0 (en) 1987-08-31
HU198685B (en) 1989-11-28
CN1030409A (zh) 1989-01-18
BE1000071A4 (fr) 1988-02-02
GB2185020A (en) 1987-07-08
NO870075D0 (no) 1987-01-08
CH672637A5 (da) 1989-12-15
JPS62228056A (ja) 1987-10-06
NL8700026A (nl) 1987-08-03
GB8700382D0 (en) 1987-02-11
NZ218868A (en) 1990-04-26
HUT46891A (en) 1988-12-28
DE3700408A1 (de) 1987-07-09
GB8600397D0 (en) 1986-02-12
AU597325B2 (en) 1990-05-31
EP0240096A1 (en) 1987-10-07
FI870062A7 (fi) 1987-07-09
PH24741A (en) 1990-10-01
IT1205849B (it) 1989-03-31
DK8787A (da) 1987-07-09
FI870062A0 (fi) 1987-01-08
FR2595351B1 (fr) 1990-07-13
AU6742087A (en) 1987-07-09
IL81201A (en) 1991-06-10
FR2595351A1 (fr) 1987-09-11
ZA87105B (en) 1987-09-30
IT8747507A0 (it) 1987-01-08
US4855314A (en) 1989-08-08
KR870007116A (ko) 1987-08-14
PT84075B (pt) 1989-07-31
GB2185020B (en) 1990-05-16
PT84075A (en) 1987-02-01
NO870075L (no) 1987-07-09

Similar Documents

Publication Publication Date Title
DK8787A (da) Indolderivater og fremgangsmaade til fremstilling deraf
DK491186A (da) Pyridonderivater og fremgangsmaade til fremstilling deraf
DK664887A (da) 3-substituerede 3-aroyloxy-propanaminer og fremgangsmaade til fremstilling deraf
NO860190L (no) Peptid-derivater og fremgangsmaate for fremstilling derav.
DK521887D0 (da) Substituerede pyrazoliner og fremgangsmaade til fremstilling deraf
DK335886D0 (da) Distamycinderivat og fremgangsmaade til fremstilling deraf
DK35687A (da) Isoquinolinderivater og fremgangsmaade til fremstilling deraf
DK335986A (da) Poly-4-aminopropyl-2-carboxamidoderivat og fremgangsmaade til fremstilling deraf
DK69989D0 (da) Benzodioxolderivater og fremgangsmaade til fremstilling deraf
DK315085D0 (da) Isoinsolinyl-alkyl-piperaziner og fremgangsmaade til fremstilling deraf
DK4187D0 (da) Triazolylquinolin-derivater og fremgangsmaade til fremstilling deraf
DK1693A (da) Pyranobenzoxadiazolderivat og fremgangsmaade til fremstilling deraf
DK477287A (da) Pyrido-benzoxadiazin-derivater og fremgangsmaade til fremstilling deraf
DK401385A (da) 7-oxomitosan-derivater og fremgangsmaade til fremstilling deraf
DK362987D0 (da) Hexahydroarylquinolizin og fremgangsmaade til fremstilling deraf
DK251087D0 (da) Dopamin-beta-hydrolaseinhibitorer og fremgangsmaade til fremstilling deraf
DK181687A (da) Piperazinderivater og fremgangsmaade til fremstiling deraf
DK487688D0 (da) Benzofuranderivater og fremgangsmaade til fremstilling deraf
DK624588A (da) 4-demethoxy-anthracyclin-derivater og fremgangsmaade til fremstilling deraf
DK446685D0 (da) Carbapenemderivater og fremgangsmaade til fremstilling deraf
DK182585D0 (da) Fosfomycinderivat og fremgangsmaade til fremstilling deraf
DK129689A (da) Ifosfamid-mesna-lyofilisat og fremgangsmaade til fremstilling deraf
DK287787A (da) Isoxazolidinonderivater og fremgangsmaade til fremstilling deraf
DK319188D0 (da) Glycerolacetalaminoacylat og fremgangsmaade til fremstilling deraf
DK301785D0 (da) Tert-butyl-gamma-dimethylamino-beta-hydroxybutyrat og fremgangsmaadetil fremstilling deraf